Training List
Handles creating, reading and updating training events.
GET /api/training/?format=api&offset=360&ordering=description
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We will present and practice:\r\n\r\nthe Nextflow software\r\nthe nf-core community and pipelines\r\nWhat is a singularity image ?\r\nWhere are installed the nf-core workflows ? Which version do I use ?\r\nHow to run a workflow and which config file is used ?\r\nWhich kind of error I can get ?\r\nHow to resume failed jobs?\r\nHow to handle genome indexes ?\r\nHow to monitor my process and then well configure my workflow ?\r\nHow do you best adjust CPU and RAM reservations?\r\nThis is NOT a bioinformatic training on a particular workflow or a training on how to develop a workflow.\r\n\r\nThis training is focused on practice. It consists of several modules with a large variety of exercises:\r\n\r\nStart at 09:00 am\r\nEnd at 17:00 pm", "homepage": "https://bioinfo.genotoul.fr/index.php/events/how-to-run-a-nf-core-nextflow-workflow-on-genotoul-2/", "is_draft": false, "costs": [ "Non-academic: 550€ + 20% taxes (TVA)", "Academic but non-INRAE: 170 € + 20% taxes (TVA)", "For INRAE's staff: 150 € no VAT charged;" ], "topics": [ "http://edamontology.org/topic_0769" ], "keywords": [ "Nextflow" ], "prerequisites": [ "Linux/Unix", "Cluster" ], "openTo": "Everyone", "accessConditions": "", "maxParticipants": 12, "contacts": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/300/?format=api" ], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [ { "id": 15, "name": "MIAT", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/MIAT/?format=api" } ], "organisedByTeams": [ { "id": 22, "name": "Genotoul-bioinfo", "url": "https://catalogue.france-bioinformatique.fr/api/team/Genotoul-bioinfo/?format=api" } ], "logo_url": "http://bioinfo.genotoul.fr/wp-content/uploads/bioinfo_logo-rvb-petit.png", "updated_at": "2025-12-01T11:57:33.124156Z", "audienceTypes": [ "Professional (continued)" ], "audienceRoles": [ "Life scientists" ], "difficultyLevel": "Novice", "trainingMaterials": [ { "id": 143, "name": "workflows nf-core", "url": "https://catalogue.france-bioinformatique.fr/api/trainingmaterial/workflows%20nf-core/?format=api" } ], "learningOutcomes": "", "hoursPresentations": 1, "hoursHandsOn": 6, "hoursTotal": 7, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/636/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/722/?format=api" ] }, { "id": 298, "name": "LINUX", "shortName": "", "description": "This training session is organized by the Genotoul bioinfo platform and aims at learning sequence analysis. This training session has been designed to familiarize yourself with the platform resources and its organization. You will learn to access the platform from your work station, what is an Linux environment and how to use it, how to create and manipulate files, how to transfer them from and to your personal computer.\r\n\r\nThis training is focused on practice. It consists of 3 modules with a large variety of exercises:\r\n\r\n- Connect to « genotoul » server (09:00 am to 10:30 am): Platform presentation, Linux basics, opening an user account, Putty installation, first connection.\r\n- Files and basics commands (10:45 am to 12:00 pm): types of files and secure access, file manipulation commands, text editors and viewers, disk space management .\r\n- Transfers and file manipulation (14:00 pm to 17:00 pm): download/transfer, compress/uncompress, utility commands and data extraction, output redirections.", "homepage": "http://bioinfo.genotoul.fr/index.php/events/linux-2-2/", "is_draft": false, "costs": [ "Non-academic: 550€ + 20% taxes (TVA)", "Academic but non-INRAE: 170 € + 20% taxes (TVA)", "For INRAE's staff: 150 € no VAT charged;" ], "topics": [ "http://edamontology.org/topic_3316" ], "keywords": [], "prerequisites": [ "none" ], "openTo": "Everyone", "accessConditions": "", "maxParticipants": 10, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [ { "id": 37, "name": "MIAT - Mathématiques et Informatique Appliquées de Toulouse", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/MIAT%20-%20Math%C3%A9matiques%20et%20Informatique%20Appliqu%C3%A9es%20de%20Toulouse/?format=api" } ], "organisedByTeams": [ { "id": 22, "name": "Genotoul-bioinfo", "url": "https://catalogue.france-bioinformatique.fr/api/team/Genotoul-bioinfo/?format=api" } ], "logo_url": "http://bioinfo.genotoul.fr/wp-content/uploads/bioinfo_logo-rvb-petit.png", "updated_at": "2025-12-01T11:56:11.488237Z", "audienceTypes": [ "Professional (continued)" ], "audienceRoles": [ "Biologists" ], "difficultyLevel": "Novice", "trainingMaterials": [], "learningOutcomes": "You will learn to access the platform genotoul bioinfo from your work station, what is an Linux environment and how to use it, how to create and manipulate files, how to transfer them from and to your personal computer.", "hoursPresentations": 3, "hoursHandsOn": 3, "hoursTotal": 6, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/476/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/608/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/447/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/667/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/632/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/528/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/719/?format=api" ] }, { "id": 388, "name": "Analysis of shotgun metagenomic data", "shortName": "", "description": "This training session is organized by the Genotoul bioinfo platform. This course is dedicated to the analysis of prokaryotic shotgun metagenomic data from Illumina and Pacbio HiFi sequencing technology. \r\n\r\nAfter an overview of metagenomics and the biases and limitations of analyses, we will look at the main steps involved in analysing metagenomic data and launch independent tools on the genobioinfo cluster.\r\nLearners will then test a workflow to automate processing on a test dataset (metagWGS ).\r\nOn the third day, learners will choose which analysis strategy to start with according to their experimental design and launch the first stage of metagWGS on their own data.\r\nBy the end of the course, trainees will be familiar with the scope, advantages and limitations of shotgun sequencing data analysis and will have started the analysis on their own data.\r\n\r\ncalendar\r\n \r\n\r\nThis training is focused on practice. It consists of several modules with a large variety of exercises:\r\n\r\nFirst Day\r\nStart at 09:00 am\r\nTour de table\r\nIntroduction to metagenomics, Illumina and Pacbio data, analysis stages, analysis limits, etc.\r\nPresentation of some key tools for each stage\r\nPractical work on the main stages launched independently\r\nEnd at 17:00 pm\r\nSecond Day\r\nStart at 09:00 am\r\nIntroduction to the advantages and disadvantages of workflows and containers\r\nLaunch of the data cleansing stage\r\nLaunch of the rest of the workflow and analysis of the multiQC report\r\nEnd at 17:00 pm\r\nThird Day – BYOD\r\nStart at 09:00 am\r\nDefine the analysis strategy and launch the start of the analysis of your own data.\r\nEnd at 17:00 pm maximum", "homepage": "https://bioinfo.genotoul.fr/index.php/events/analysis-of-shotgun-metagenomic-data/", "is_draft": false, "costs": [ "Non-academic for non-academic: 1650€ + 20% taxes (TVA)", "Academic non-INRAE for academic but non-INRAE: 510 € + 20% taxes (TVA)", "INRAE for INRAE's staff: 450 € no VAT charged" ], "topics": [ "http://edamontology.org/topic_3174" ], "keywords": [ "NGS Data Analysis", "Metagenomics" ], "prerequisites": [ "Linux/Unix", "Cluster" ], "openTo": "Everyone", "accessConditions": "", "maxParticipants": 12, "contacts": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/300/?format=api" ], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [ { "id": 88, "name": "BioinfOmics", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/BioinfOmics/?format=api" }, { "id": 82, "name": "INRAE", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INRAE/?format=api" }, { "id": 37, "name": "MIAT - Mathématiques et Informatique Appliquées de Toulouse", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/MIAT%20-%20Math%C3%A9matiques%20et%20Informatique%20Appliqu%C3%A9es%20de%20Toulouse/?format=api" } ], "organisedByTeams": [ { "id": 22, "name": "Genotoul-bioinfo", "url": "https://catalogue.france-bioinformatique.fr/api/team/Genotoul-bioinfo/?format=api" } ], "logo_url": "http://bioinfo.genotoul.fr/wp-content/uploads/bioinfo_logo-rvb-petit.png", "updated_at": "2025-12-01T11:55:10.179665Z", "audienceTypes": [ "Professional (continued)" ], "audienceRoles": [ "Life scientists", "Biologists", "Bioinformaticians" ], "difficultyLevel": "Intermediate", "trainingMaterials": [ { "id": 151, "name": "Metagenomic training", "url": "https://catalogue.france-bioinformatique.fr/api/trainingmaterial/Metagenomic%20training/?format=api" } ], "learningOutcomes": "", "hoursPresentations": 3, "hoursHandsOn": 15, "hoursTotal": 18, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/670/?format=api" ] }, { "id": 144, "name": "FROGS formation : tools for bioinformatics and statistics analyses with amplicon metagenomics data", "shortName": "", "description": "This training session, organized by Bioinfo Genotoul, Sigenae, NED (GenPhySE) and TWB, is designed to help you to deal with NGS data of 16S, 18S ... DNA produced with MiSeq from Illumina and Roche 454 technologies in the Galaxy workbench.\nYou will discover how to use our Galaxy instance, clean reads, clusterize them, do the taxonomic affiliation and perform statistics to interpret your results.\nPrerequisites: knowledge of R or in another programming language\n", "homepage": "http://bioinfo.genotoul.fr/index.php/events/metagenomic-amplicons-and-stats-with…", "is_draft": false, "costs": [ "Priced" ], "topics": [], "keywords": [ "NGS Data Analysis", "Metagenomics", "metatranscriptomics", "Galaxy" ], "prerequisites": [], "openTo": "Internal personnel", "accessConditions": "Subscribe by the web page : http://bioinfo.genotoul.fr/index.php/training-2/galaxy-training/.\nPrices : 165 euros per day for academic people, 550 per day otherwise.\n", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "https://ressources.france-bioinformatique.fr/sites/default/files/FROGS_logo_0.png", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/273/?format=api" ] }, { "id": 75, "name": "Galaxy: metagenomic: sequence analysis of amplicons from MiSeq and 454 sequencing with FROGS with Galaxy first step and statistics", "shortName": "", "description": "This training session, organized by Bioinfo Genotoul, Sigenae, NED (GenPhySE) and TWB, is designed to help you to deal with NGS data of 16S, 18S ... DNA produced with MiSeq from Illumina and Roche 454 technologies in the Galaxy workbench.\nYou will discover how to use our Galaxy instance, clean reads, clusterize them, do the taxonomic affiliation and perform statistics to interpret your results.\nPrerequisites: knowledge of R or in another programming language\n", "homepage": "http://bioinfo.genotoul.fr/index.php", "is_draft": false, "costs": [], "topics": [], "keywords": [ "Galaxy" ], "prerequisites": [], "openTo": "Internal personnel", "accessConditions": "An account on the platform Bioinfo Genotoul is necessary (request a form on the website), you need to register (via the website) and pay 165 euros a day for academic and 550 euros a day for a private\n", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [] }, { "id": 64, "name": "Read alignment and SNP calling", "shortName": "", "description": "This training session, organized jointly with the Sigenae platform, is designed to help you deal with NGS data, in particular Roche 454 and Illumina Solexa technologies. You will discover the new sequence formats, the new assembly formats and the known biases of these technologies. You will use mapping on reference genome software, polymorphisms detection (with the GATK pipeline), polymorphisms annotation and alignment visualization software. Organized jointly by the Sigenae and bioinfo genotoul platforms.\n", "homepage": "http://bioinfo.genotoul.fr/index.php/events/alignment-and-small-size-variants-ca…", "is_draft": false, "costs": [ "Priced" ], "topics": [], "keywords": [ "NGS Data Analysis", "Variant analysis", "Genomics (DNA-seq)" ], "prerequisites": [], "openTo": "Internal personnel", "accessConditions": "You need to register (via the website) and pay 165 euros a day for academic and 550 euros a day for a private.\n", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [] }, { "id": 332, "name": "SHORT-READ ALIGNMENT AND SMALL SIZE VARIANTS CALLING", "shortName": "", "description": "This training session, organized jointly with the Sigenae platform, is designed to introduce NGS data, in particular Illumina Solexa technologies with command line. You will discover the new sequence formats, the assembly formats and the known biases of these technologies. You will use mapping on reference genome software, polymorphisms detection with the GATK pipeline and alignment visualization software.\r\n\r\nThis training is focused on the practice. It consists of modules with a large variety of exercises:\r\n\r\nDay 1 (09:00 am to 12:30 am): Fastq format / Sequence quality. Read mapping.\r\nDay 1 (14:00 pm to 17:00 pm): SAM format. Visualisation.\r\nDay 2 (09:00 am to 17:00 am): Variant calling. VCF format. Variant annotation (SNPeff / SNPsift).\r\n \r\nThe session will take place in the room ‘salle de formation’ at INRAE center of Toulouse-Auzeville.\r\n\r\nPrerequisites: ability to use a Unix environment (see Unix training) and Cluster (see Cluster training).\r\n \r\nTool box: FastQC, BWA, Samtools, Picard tools, GATK, SnpSift / SnpEff, IGV.", "homepage": "https://bioinfo.genotoul.fr/index.php/events/alignment-and-small-size-variants-calling/", "is_draft": false, "costs": [ "Non-academic: 550€ + 20% taxes (TVA)", "Academic but non-INRAE: 170 € + 20% taxes (TVA)", "For INRAE's staff: 150 € no VAT charged;" ], "topics": [ "http://edamontology.org/topic_0102", "http://edamontology.org/topic_2885" ], "keywords": [], "prerequisites": [ "Linux/Unix", "Cluster" ], "openTo": "Everyone", "accessConditions": "", "maxParticipants": 12, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [ { "id": 37, "name": "MIAT - Mathématiques et Informatique Appliquées de Toulouse", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/MIAT%20-%20Math%C3%A9matiques%20et%20Informatique%20Appliqu%C3%A9es%20de%20Toulouse/?format=api" } ], "organisedByTeams": [ { "id": 22, "name": "Genotoul-bioinfo", "url": "https://catalogue.france-bioinformatique.fr/api/team/Genotoul-bioinfo/?format=api" } ], "logo_url": "https://bioinfo.genotoul.fr/wp-content/uploads/sigenae-text-black-1.png", "updated_at": "2025-12-01T11:54:41.351028Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "Novice", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/634/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/530/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/724/?format=api" ] }, { "id": 275, "name": "Single-Cell : Transcriptomics, Spatial and Long reads", "shortName": "SincellTE", "description": "This workshop focuses on the large-scale study of heterogeneity across individual cells from a genomic, transcriptomic and epigenomic point of view. New technological developments enable the characterization of molecular information at a single cell resolution for large numbers of cells. The high dimensional omics data that these technologies produce raise novel methodological challenges for the analysis. In this regard, dedicated bioinformatics and statistical methods have been developed in order to extract robust information.\r\n\r\nThe workshop aims to provide such methods for engineers and researchers directly involved in functional genomics projects making use of single-cell technologies. A wide range of single cell topics will be covered in lectures, demonstrations and practical classes. Among others, the areas and issues to be addressed will include the choice of the most appropriate single-cell sequencing technology, the experimental design and the bioinformatics and statistical methods and pipelines. For this edition, new courses/practicals will focus on spatial transcriptomics, cell phenotyping and additional multi-omics.\r\n\r\nA wide range of single cell topics will be covered in lectures, demonstrations and practical classes. Among others, the areas and issues to be addressed will include the choice of the most appropriate single-cell sequencing technology, the experimental design and the bioinformatics and statistical methods and pipelines. For this edition, new courses/practicals will focus on spatial transcriptomics, cell phenotyping and additional multi-omics.\r\n\r\nRequirements : Participants must have prior experience on NGS data analysis with everyday use of R and good knowledge of Unix command line. Before the training, participants will be asked to familiarize themselves with the processing and primary analyses steps of scRNA-seq datasets with provided pedagogic material.\r\n\r\nIt is not necessary to have personal single-cell data to analyse.", "homepage": "", "is_draft": false, "costs": [ "Priced" ], "topics": [], "keywords": [], "prerequisites": [ "Master", "Autre (Diplôme universitaire, école d'ingénieur ...)" ], "openTo": "Everyone", "accessConditions": "Participants must have prior experience on NGS data analysis with everyday use of R and/or Python and good knowledge of Unix command line. Before the training, participants are advised to familiarize themselves with the processing and primary analyses steps of scRNA-seq datasets. \r\nIt is not necessary to have personal single-cell data to analyse.", "maxParticipants": 30, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [ { "id": 4, "name": "IFB - ELIXIR-FR", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/IFB%20-%20ELIXIR-FR/?format=api" } ], "organisedByTeams": [], "logo_url": "https://ressources.france-bioinformatique.fr/sites/default/files/sincellTE_logo_0_2.png", "updated_at": "2024-03-20T09:31:42.144175Z", "audienceTypes": [], "audienceRoles": [ "Researchers", "Life scientists", "Biologists", "Bioinformaticians" ], "difficultyLevel": "Intermediate", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [ "https://catalogue.france-bioinformatique.fr/api/event/199/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/405/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/422/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/177/?format=api", "https://catalogue.france-bioinformatique.fr/api/event/606/?format=api" ] }, { "id": 35, "name": "REPET: detection and annotation of repeats", "shortName": "", "description": "Training and accompanying at URGI (one week) on data provided by the trainee: use of the 2 main pipelines (TEdenovo et TEannot) + post analysis of results\n", "homepage": "", "is_draft": false, "costs": [], "topics": [], "keywords": [ "Bioinformatics and Plant Genomics" ], "prerequisites": [], "openTo": "Internal personnel", "accessConditions": "Information and registering at: urgi-contact@versailles.inra.fr\n", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [] }, { "id": 49, "name": "Introduction to molecular phylogeny", "shortName": "", "description": "Training organized by CNRS Entreprises\n", "homepage": "https://cnrsformation.cnrs.fr/stage-17008-Phylogenie-moleculaire-%28Lyon%29.html", "is_draft": false, "costs": [], "topics": [], "keywords": [ "Phylogeny", "Evolution and Phylogeny", "Molecular evolution", "Tree of Life", "Phylogenomics", "Genes and genomes" ], "prerequisites": [], "openTo": "Internal personnel", "accessConditions": "Some knowledge in mathematics and statistics.\n", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [] }, { "id": 15, "name": "IFSBM", "shortName": "", "description": "\nUFR médecine Paris-Sud (mai 2015). Big data en médecine. Acquisition et analyse des données de haut débit dans le but de détecter des variants génomiques (CGH, exome, génome), étudier les profils d’expression ou le statut épigénétique des cellules (expression array, RNA-seq, ChiP-seq, medip-seq).\n \nUFR médecine Paris-Sud (janvier 2015) Méthodologie en biologie moléculaire et cellulaire et analyse d’article\n\n", "homepage": "", "is_draft": false, "costs": [], "topics": [], "keywords": [], "prerequisites": [ "Autre (Diplôme universitaire, école d'ingénieur ...)" ], "openTo": "Internal personnel", "accessConditions": "", "maxParticipants": null, "contacts": [], "elixirPlatforms": [], "communities": [], "sponsoredBy": [], "organisedByOrganisations": [], "organisedByTeams": [], "logo_url": "", "updated_at": "2022-06-02T11:50:50.812642Z", "audienceTypes": [], "audienceRoles": [], "difficultyLevel": "", "trainingMaterials": [], "learningOutcomes": "", "hoursPresentations": null, "hoursHandsOn": null, "hoursTotal": null, "personalised": null, "event_set": [] }, { "id": 262, "name": "Bioinformatics of protein--protein interactions for wet lab scientists", "shortName": "", "description": "Understanding physical and functional interactions between molecules in living systems is crucial in many biological processes. Several powerful methods and techniques have been developed to generate molecular interaction data, focusing mainly on protein-protein interactions (PPIs). In particular, PPIs involving partially or completely unstructured regions are building blocks of regulatory and signalling networks that control cell response to external and internal cues. 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