{"count":136,"next":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=100&ordering=-description","previous":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=60&ordering=-description","results":[{"id":8,"uri":"http://edamontology.org/topic_3077","label":"Data acquisition","synonyms":["Data collection"],"description":"The acquisition of data, typically measurements of physical systems using any type of sampling system, or by another other means."},{"id":90,"uri":"http://edamontology.org/topic_0781","label":"Virology","synonyms":null,"description":"Study of viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation."},{"id":115,"uri":"http://edamontology.org/topic_0166","label":"Protein structural motifs and surfaces","synonyms":["Protein surfaces","Protein structural features","Protein 3D motifs","Structural motifs","Protein structural motifs"],"description":"Structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules."},{"id":93,"uri":"http://edamontology.org/topic_0199","label":"Genetic variation","synonyms":["DNA variation","Somatic mutations","Genomic variation","Mutation","Polymorphism"],"description":"Stable, naturally occuring mutations in a nucleotide sequence including alleles, naturally occurring mutations such as single base nucleotide substitutions, deletions and insertions, RFLPs and other polymorphisms."},{"id":20,"uri":"http://edamontology.org/topic_0154","label":"Small molecules","synonyms":["Peptides and amino acids","Toxins and targets","Drugs and target structures","Drug targets","Peptides","Drug structures","Metabolite structures","Amino acids","Toxins","Targets","Chemical structures","Target structures"],"description":"Small molecules of biological significance, typically archival, curation, processing and analysis of structural information."},{"id":116,"uri":"http://edamontology.org/topic_3542","label":"Protein secondary structure","synonyms":["Protein super-secondary structure","Protein features (secondary structure)"],"description":"Secondary structure (predicted or real) of a protein, including super-secondary structure."},{"id":92,"uri":"http://edamontology.org/topic_3320","label":"RNA splicing","synonyms":["Alternative splicing","Splice sites"],"description":"RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons."},{"id":118,"uri":"http://edamontology.org/topic_0099","label":"RNA","synonyms":["Small RNA"],"description":"RNA sequences and structures."},{"id":108,"uri":"http://edamontology.org/topic_3523","label":"RNAi experiment","synonyms":null,"description":"RNAi experiments."},{"id":18,"uri":"http://edamontology.org/topic_0092","label":"Data visualisation","synonyms":["Data rendering"],"description":"Rendering (drawing on a computer screen) or visualisation of molecular sequences, structures or other biomolecular data."},{"id":106,"uri":"http://edamontology.org/topic_3520","label":"Proteomics experiment","synonyms":["2D PAGE experiment","Spectrum demultiplexing","Mass spectrometry experiments","MS","Northern blot experiment","MS experiments","DIA","Mass spectrometry","Data-independent acquisition"],"description":"Proteomics experiments."},{"id":99,"uri":"http://edamontology.org/topic_0736","label":"Protein folds and structural domains","synonyms":["Protein domains","Protein membrane regions","Protein folds","Protein transmembrane regions","Protein topological domains","Protein structural domains","Intramembrane regions","Transmembrane regions"],"description":"Protein tertiary structural domains and folds in a protein or polypeptide chain."},{"id":65,"uri":"http://edamontology.org/topic_0749","label":"Transcription factors and regulatory sites","synonyms":["Attenuators","Transcription factors","GC signals","Terminators","-10 signals","TFBS","Isochores","-35 signals","Promoters","Enhancers","Transcriptional regulatory sites","TATA signals","CCAAT box","Transcription factor binding sites","CAAT signals","CAT box","CpG islands"],"description":"Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."},{"id":113,"uri":"http://edamontology.org/topic_2814","label":"Protein structure analysis","synonyms":["Protein tertiary structure","Protein structure"],"description":"Protein secondary or tertiary structural data and/or associated annotation."},{"id":24,"uri":"http://edamontology.org/topic_0128","label":"Protein interactions","synonyms":["Protein interaction networks","Protein-ligand interactions","Protein-nucleic acid interactions","Protein-DNA interactions","Protein-DNA interaction","Protein interaction map","Protein-RNA interaction","Protein-RNA interactions","Protein interactome","Protein-protein interactions"],"description":"Protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions."},{"id":111,"uri":"http://edamontology.org/topic_0121","label":"Proteomics","synonyms":["Peptide identification","Quantitative proteomics","MS-based targeted proteomics","Targeted proteomics","Metaproteomics","MS-based untargeted proteomics","Discovery proteomics","Top-down proteomics","Protein and peptide identification","Bottom-up proteomics"],"description":"Protein and peptide identification, especially in the study of whole proteomes of organisms."},{"id":86,"uri":"http://edamontology.org/topic_0780","label":"Plant biology","synonyms":["Plant","Plant physiology","Plant anatomy","Plant ecology","Plant genetics","Botany","Plant science","Plants","Plant cell biology"],"description":"Plants, e.g. information on a specific plant genome including molecular sequences, genes and annotation."},{"id":48,"uri":"http://edamontology.org/topic_3298","label":"Phenomics","synonyms":null,"description":"Phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors."},{"id":2,"uri":"http://edamontology.org/topic_3519","label":"PCR experiment","synonyms":["Polymerase chain reaction","Real Time Quantitative PCR","RT-qPCR","Quantitative PCR"],"description":"PCR experiments, e.g. quantitative real-time PCR."},{"id":70,"uri":"http://edamontology.org/topic_0623","label":"Gene and protein families","synonyms":["Gene system","Gene families","Gene family","Protein sequence classification","Protein families","Genes, gene family or system"],"description":"Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."}]}