{"count":136,"next":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=80&ordering=uri","previous":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=40&ordering=uri","results":[{"id":63,"uri":"http://edamontology.org/topic_3053","label":"Genetics","synonyms":["Genes","Heredity"],"description":"The study of genes, genetic variation and heredity in living organisms."},{"id":102,"uri":"http://edamontology.org/topic_3056","label":"Population genetics","synonyms":null,"description":"The distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow."},{"id":61,"uri":"http://edamontology.org/topic_3063","label":"Medical informatics","synonyms":["Biomedical informatics","Health and disease","Clinical informatics","Healthcare informatics","Health informatics"],"description":"The application of information technology to health, disease and biomedicine."},{"id":57,"uri":"http://edamontology.org/topic_3064","label":"Developmental biology","synonyms":["Development"],"description":"How organisms grow and develop."},{"id":54,"uri":"http://edamontology.org/topic_3065","label":"Embryology","synonyms":null,"description":"The development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage."},{"id":100,"uri":"http://edamontology.org/topic_3068","label":"Literature and language","synonyms":["Scientific literature","Literature","Language","References","Documentation","Citations","Bibliography"],"description":"The scientific literature, language processing, reference information, and documentation."},{"id":87,"uri":"http://edamontology.org/topic_3071","label":"Biological databases","synonyms":["Data management","Databases and information systems","Information systems"],"description":"The development and use of architectures, policies, practices and procedures for management of data."},{"id":8,"uri":"http://edamontology.org/topic_3077","label":"Data acquisition","synonyms":["Data collection"],"description":"The acquisition of data, typically measurements of physical systems using any type of sampling system, or by another other means."},{"id":25,"uri":"http://edamontology.org/topic_3125","label":"DNA binding sites","synonyms":["Matrix-attachment region","Ribosome binding sites","Scaffold-attachment region","Matrix/scaffold attachment region","Nucleosome exclusion sequences","Restriction sites"],"description":"Nucleic acids binding to some other molecule."},{"id":23,"uri":"http://edamontology.org/topic_3168","label":"Sequencing","synonyms":["Panels","Primer walking","DNA-Seq","High-throughput sequencing","Chromosome walking","Next generation sequencing","NGS data analysis","Next gen sequencing","High throughput sequencing","Targeted next-generation sequencing panels","NGS","Sanger sequencing","Clone verification","DNase-Seq"],"description":"The determination of complete (typically nucleotide) sequences, including those of genomes (full genome sequencing, de novo sequencing and resequencing), amplicons and transcriptomes."},{"id":105,"uri":"http://edamontology.org/topic_3169","label":"ChIP-seq","synonyms":["ChIP-sequencing","Chip sequencing","Chip Seq","ChIP-exo","Chip-sequencing"],"description":"The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."},{"id":13,"uri":"http://edamontology.org/topic_3170","label":"RNA-Seq","synonyms":["RNA sequencing","RNA-Seq analysis","Whole transcriptome shotgun sequencing","WTSS","Small-Seq","Small RNA sequencing","Small RNA-Seq","miRNA-seq","MicroRNA sequencing","Transcriptome profiling"],"description":"A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."},{"id":64,"uri":"http://edamontology.org/topic_3172","label":"Metabolomics","synonyms":["Exometabolomics","Metabolites","Metabonomics","MS-based metabolomics","MS-based untargeted metabolomics","NMR-based metabolomics","Metabolome","LC-MS-based metabolomics","MS-based targeted metabolomics","Mass spectrometry-based metabolomics"],"description":"The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism."},{"id":129,"uri":"http://edamontology.org/topic_3173","label":"Epigenomics","synonyms":[],"description":"The study of the epigenetic modifications of a whole cell, tissue, organism etc."},{"id":45,"uri":"http://edamontology.org/topic_3174","label":"Metagenomics","synonyms":["Biome sequencing","Shotgun metagenomics"],"description":"The study of genetic material recovered from environmental samples, and associated environmental data."},{"id":128,"uri":"http://edamontology.org/topic_3175","label":"Structural variation","synonyms":["DNA structural variation","Genomic structural variation","Deletion","Duplication","Insertion","Inversion","Translocation"],"description":"Variation in chromosome structure including microscopic and submicroscopic types of variation such as deletions, duplications, copy-number variants, insertions, inversions and translocations."},{"id":119,"uri":"http://edamontology.org/topic_3292","label":"Biochemistry","synonyms":["Glycomics","Phytochemistry","Biological chemistry","Pathobiochemistry"],"description":"Chemical substances and physico-chemical processes and that occur within living organisms."},{"id":59,"uri":"http://edamontology.org/topic_3293","label":"Phylogenetics","synonyms":null,"description":"The study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences)."},{"id":48,"uri":"http://edamontology.org/topic_3298","label":"Phenomics","synonyms":null,"description":"Phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors."},{"id":71,"uri":"http://edamontology.org/topic_3299","label":"Evolutionary biology","synonyms":["Evolution"],"description":"The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."}]}