{"count":136,"next":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=60&ordering=uri","previous":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=20&ordering=uri","results":[{"id":99,"uri":"http://edamontology.org/topic_0736","label":"Protein folds and structural domains","synonyms":["Protein domains","Protein membrane regions","Protein folds","Protein transmembrane regions","Protein topological domains","Protein structural domains","Intramembrane regions","Transmembrane regions"],"description":"Protein tertiary structural domains and folds in a protein or polypeptide chain."},{"id":65,"uri":"http://edamontology.org/topic_0749","label":"Transcription factors and regulatory sites","synonyms":["Attenuators","Transcription factors","GC signals","Terminators","-10 signals","TFBS","Isochores","-35 signals","Promoters","Enhancers","Transcriptional regulatory sites","TATA signals","CCAAT box","Transcription factor binding 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(docking)."},{"id":113,"uri":"http://edamontology.org/topic_2814","label":"Protein structure analysis","synonyms":["Protein tertiary structure","Protein structure"],"description":"Protein secondary or tertiary structural data and/or associated annotation."},{"id":11,"uri":"http://edamontology.org/topic_2815","label":"Human biology","synonyms":["Humans"],"description":"The study of human beings in general, including the human genome and proteome."},{"id":21,"uri":"http://edamontology.org/topic_2828","label":"X-ray diffraction","synonyms":["X-ray crystallography","X-ray microscopy","Crystallography"],"description":"The study of matter and their structure by means of the diffraction of X-rays, typically the diffraction pattern caused by the regularly spaced atoms of a crystalline sample."},{"id":120,"uri":"http://edamontology.org/topic_2840","label":"Toxicology","synonyms":["Toxicoinformatics","Computational toxicology"],"description":"Toxins and the adverse effects of these chemical substances on living organisms."},{"id":4,"uri":"http://edamontology.org/topic_2885","label":"DNA polymorphism","synonyms":["Microsatellites","SNP","Variable number of tandem repeat polymorphism","snps","Single nucleotide polymorphism","VNTR","RFLP"],"description":"DNA polymorphism."},{"id":67,"uri":"http://edamontology.org/topic_3050","label":"Biodiversity","synonyms":null,"description":"The degree of variation of life forms within a given ecosystem, biome or an entire planet."}]}