{"count":136,"next":null,"previous":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=100&ordering=description","results":[{"id":46,"uri":"http://edamontology.org/topic_3387","label":"Marine biology","synonyms":null,"description":"The study of organisms in the ocean or brackish waters."},{"id":60,"uri":"http://edamontology.org/topic_3325","label":"Rare diseases","synonyms":["Rare_disease"],"description":"The study of rare diseases."},{"id":129,"uri":"http://edamontology.org/topic_3173","label":"Epigenomics","synonyms":[],"description":"The study of the epigenetic modifications of a whole cell, tissue, organism etc."},{"id":81,"uri":"http://edamontology.org/topic_0797","label":"Comparative genomics","synonyms":null,"description":"The study (typically comparison) of the sequence, structure or function of multiple genomes."},{"id":64,"uri":"http://edamontology.org/topic_3172","label":"Metabolomics","synonyms":["Exometabolomics","Metabolites","Metabonomics","MS-based metabolomics","MS-based untargeted metabolomics","NMR-based metabolomics","Metabolome","LC-MS-based metabolomics","MS-based targeted metabolomics","Mass spectrometry-based metabolomics"],"description":"The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism."},{"id":16,"uri":"http://edamontology.org/topic_3316","label":"Computer science","synonyms":["Cloud computing","High performance computing","High-performance computing","HPC"],"description":"The theory and practical use of computer systems."},{"id":53,"uri":"http://edamontology.org/topic_3383","label":"Bioimaging","synonyms":["Biological imaging"],"description":"The use of imaging techniques to understand biology."},{"id":132,"uri":"http://edamontology.org/topic_3421","label":"Surgery","synonyms":["Transplantation"],"description":"The use of operative, manual and instrumental techniques on a patient to investigate and/or treat a pathological condition or help improve bodily function or appearance."},{"id":29,"uri":"http://edamontology.org/topic_3306","label":"Biophysics","synonyms":["Medical physics"],"description":"The use of physics to study biological system."},{"id":47,"uri":"http://edamontology.org/topic_3382","label":"Imaging","synonyms":["Optical super resolution microscopy","Microscopy","Photonic force microscopy","Photonic microscopy","Diffraction experiment","Microscopy imaging"],"description":"The visual representation of an object."},{"id":76,"uri":"http://edamontology.org/topic_3332","label":"Computational chemistry","synonyms":null,"description":"Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of chemical systems."},{"id":131,"uri":"http://edamontology.org/topic_3305","label":"Public health and epidemiology","synonyms":["Epidemiology","Public health"],"description":"Topic concerning the the patterns, cause, and effect of disease within populations."},{"id":120,"uri":"http://edamontology.org/topic_2840","label":"Toxicology","synonyms":["Toxicoinformatics","Computational toxicology"],"description":"Toxins and the adverse effects of these chemical substances on living organisms."},{"id":26,"uri":"http://edamontology.org/topic_3512","label":"Gene transcripts","synonyms":["Exons","Introns","PolyA site","EST","Gene transcript features","Transit peptide coding sequence","mRNA","Fusion transcripts","Coding RNA","PolyA signal","mRNA features","cDNA","Signal peptide coding sequence"],"description":"Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."},{"id":128,"uri":"http://edamontology.org/topic_3175","label":"Structural variation","synonyms":["DNA structural variation","Genomic structural variation","Deletion","Duplication","Insertion","Inversion","Translocation"],"description":"Variation in chromosome structure including microscopic and submicroscopic types of variation such as deletions, duplications, copy-number variants, insertions, inversions and translocations."},{"id":72,"uri":"http://edamontology.org/topic_0622","label":"Genomics","synonyms":["Exomes","Synthetic genomics","Genome annotation","Whole genomes","Personal genomics","Genomes","Viral genomics"],"description":"Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."}]}