{"count":137,"next":null,"previous":"https://catalogue.france-bioinformatique.fr/api/topic/?format=json&limit=20&offset=100","results":[{"id":51,"uri":"http://edamontology.org/topic_3308","label":"Transcriptomics","synonyms":["Transcriptome","Comparative transcriptomics","Metatranscriptomics"],"description":"The analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc."},{"id":58,"uri":"http://edamontology.org/topic_2229","label":"Cell biology","synonyms":["Protein subcellular localization","Cellular processes","Cells"],"description":"Cells, such as key genes and proteins involved in the cell cycle."},{"id":68,"uri":"http://edamontology.org/topic_0194","label":"Phylogenomics","synonyms":null,"description":"The integrated study of evolutionary relationships and whole genome data, for example, in the analysis of species trees, horizontal gene transfer and evolutionary reconstruction."},{"id":79,"uri":"http://edamontology.org/topic_2259","label":"Systems biology","synonyms":["Biological system modelling","Systems modelling","Biological modelling"],"description":"The holistic modelling and analysis of complex biological systems and the interactions therein."},{"id":57,"uri":"http://edamontology.org/topic_3064","label":"Developmental biology","synonyms":["Development"],"description":"How organisms grow and develop."},{"id":89,"uri":"http://edamontology.org/topic_3957","label":"Protein interaction experiment","synonyms":["Phage display","Yeast one-hybrid","Co-immunoprecipitation","Yeast two-hybrid"],"description":"An experiment for studying protein-protein interactions."},{"id":87,"uri":"http://edamontology.org/topic_3071","label":"Biological databases","synonyms":["Data management","Databases and information systems","Information systems"],"description":"The development and use of architectures, policies, practices and procedures for management of data."},{"id":107,"uri":"http://edamontology.org/topic_3372","label":"Software engineering","synonyms":["Computer programming","Algorithms","Software development","Data structures","Programming languages"],"description":"The process that leads from an original formulation of a computing problem to executable programs."},{"id":24,"uri":"http://edamontology.org/topic_0128","label":"Protein interactions","synonyms":["Protein interaction networks","Protein-ligand interactions","Protein-nucleic acid interactions","Protein-DNA interactions","Protein-DNA interaction","Protein interaction map","Protein-RNA interaction","Protein-RNA interactions","Protein interactome","Protein-protein interactions"],"description":"Protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions."},{"id":14,"uri":"http://edamontology.org/topic_2269","label":"Statistics and probability","synonyms":["Biostatistics","Multivariate statistics","Bayesian methods","Gaussian processes","Probability","Markov processes","Probabilistic graphical model","Inferential statistics","Descriptive statistics","Statistics"],"description":"The application of statistical methods to biological problems."},{"id":85,"uri":"http://edamontology.org/topic_0610","label":"Ecology","synonyms":["Ecological informatics","Ecoinformatics","Ecosystem science","Computational ecology"],"description":"The ecological and environmental sciences and especially the application of information technology (ecoinformatics)."},{"id":12,"uri":"http://edamontology.org/topic_0102","label":"Mapping","synonyms":["Linkage","Synteny","Genetic linkage","Linkage mapping"],"description":"The mapping of complete (typically nucleotide) sequences. Mapping (in the sense of short read alignment, or more generally, just alignment) has application in RNA-Seq analysis (mapping of transcriptomics reads), variant discovery (e.g. mapping of exome capture), and re-sequencing (mapping of WGS reads)."},{"id":77,"uri":"http://edamontology.org/topic_0602","label":"Molecular interactions, pathways and networks","synonyms":["Networks","Gene regulatory networks","Interactome","Molecular interactions","Disease pathways","Biological pathways","Signaling pathways","Pathways","Environmental information processing pathways","Cellular process pathways","Genetic information processing pathways","Signal transduction pathways","Biological models","Metabolic pathways","Biological networks","Interactions"],"description":"Molecular interactions, biological pathways, networks and other models."},{"id":65,"uri":"http://edamontology.org/topic_0749","label":"Transcription factors and regulatory sites","synonyms":["Attenuators","Transcription factors","GC signals","Terminators","-10 signals","TFBS","Isochores","-35 signals","Promoters","Enhancers","Transcriptional regulatory sites","TATA signals","CCAAT box","Transcription factor binding sites","CAAT signals","CAT box","CpG islands"],"description":"Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."},{"id":137,"uri":"http://edamontology.org/topic_3796","label":"Population genomics","synonyms":[],"description":"Large-scale study (typically comparison) of DNA sequences of populations."},{"id":70,"uri":"http://edamontology.org/topic_0623","label":"Gene and protein families","synonyms":["Gene system","Gene families","Gene family","Protein sequence classification","Protein families","Genes, gene family or system"],"description":"Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."},{"id":84,"uri":"http://edamontology.org/topic_3810","label":"Agricultural science","synonyms":["","Plant pathology","Animal nutrition","Agricultural biotechnology","Horticulture","Animal husbandry","Agricultural economics","Phytomedicine","Food process engineering","Plant breeding","Animal breeding","Farming systems research","Plant nutrition","Food security","Soil science","Plant cultivation"],"description":"Multidisciplinary study, research and development within the field of agriculture."}]}