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{
"count": 127,
"next": "https://catalogue.france-bioinformatique.fr/api/topic/?format=api&limit=20&offset=20&ordering=id",
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{
"id": 1,
"uri": "http://edamontology.org/topic_3697",
"label": "Microbial ecology",
"synonyms": [
"Molecular community analysis",
"Community analysis",
"Microbiome",
"Environmental microbiology"
],
"description": "The ecology of microorganisms including their relationship with one another and their environment."
},
{
"id": 2,
"uri": "http://edamontology.org/topic_3519",
"label": "PCR experiment",
"synonyms": [
"Polymerase chain reaction",
"Real Time Quantitative PCR",
"RT-qPCR",
"Quantitative PCR"
],
"description": "PCR experiments, e.g. quantitative real-time PCR."
},
{
"id": 3,
"uri": "http://edamontology.org/topic_0798",
"label": "Mobile genetic elements",
"synonyms": [
"Transposons"
],
"description": "Mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns."
},
{
"id": 4,
"uri": "http://edamontology.org/topic_2885",
"label": "DNA polymorphism",
"synonyms": [
"Microsatellites",
"SNP",
"Variable number of tandem repeat polymorphism",
"snps",
"Single nucleotide polymorphism",
"VNTR",
"RFLP"
],
"description": "DNA polymorphism."
},
{
"id": 5,
"uri": "http://edamontology.org/topic_3572",
"label": "Data quality management",
"synonyms": [
"Data integrity",
"Data cleaning",
"Data quality",
"Data clean-up"
],
"description": "The quality, integrity, and cleaning up of data."
},
{
"id": 6,
"uri": "http://edamontology.org/topic_3365",
"label": "Data architecture, analysis and design",
"synonyms": [
"Data analysis",
"Data design",
"Data architecture"
],
"description": "The development of policies, models and standards that cover data acquisition, storage and integration, such that it can be put to use, typically through a process of systematically applying statistical and / or logical techniques to describe, illustrate, summarise or evaluate data."
},
{
"id": 7,
"uri": "http://edamontology.org/topic_3489",
"label": "Database management",
"synonyms": [
"Content management",
"Document, record and content management",
"Record management",
"Data maintenance",
"File management",
"Database administration",
"Document management"
],
"description": "The general handling of data stored in digital archives such as databanks, databases proper, web portals and other data resources."
},
{
"id": 8,
"uri": "http://edamontology.org/topic_3077",
"label": "Data acquisition",
"synonyms": [
"Data collection"
],
"description": "The acquisition of data, typically measurements of physical systems using any type of sampling system, or by another other means."
},
{
"id": 9,
"uri": "http://edamontology.org/topic_0637",
"label": "Taxonomy",
"synonyms": null,
"description": "Organism classification, identification and naming."
},
{
"id": 10,
"uri": "http://edamontology.org/topic_0077",
"label": "Nucleic acids",
"synonyms": [
"Nucleic acid properties",
"Nucleic acid physicochemistry",
"Nucleic acid informatics",
"Nucleic acid bioinformatics"
],
"description": "The processing and analysis of nucleic acid sequence, structural and other data."
},
{
"id": 11,
"uri": "http://edamontology.org/topic_2815",
"label": "Human biology",
"synonyms": [
"Humans"
],
"description": "The study of human beings in general, including the human genome and proteome."
},
{
"id": 12,
"uri": "http://edamontology.org/topic_0102",
"label": "Mapping",
"synonyms": [
"Linkage",
"Synteny",
"Genetic linkage",
"Linkage mapping"
],
"description": "The mapping of complete (typically nucleotide) sequences. Mapping (in the sense of short read alignment, or more generally, just alignment) has application in RNA-Seq analysis (mapping of transcriptomics reads), variant discovery (e.g. mapping of exome capture), and re-sequencing (mapping of WGS reads)."
},
{
"id": 13,
"uri": "http://edamontology.org/topic_3170",
"label": "RNA-Seq",
"synonyms": [
"RNA sequencing",
"RNA-Seq analysis",
"Whole transcriptome shotgun sequencing",
"WTSS",
"Small-Seq",
"Small RNA sequencing",
"Small RNA-Seq",
"miRNA-seq",
"MicroRNA sequencing",
"Transcriptome profiling"
],
"description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
},
{
"id": 14,
"uri": "http://edamontology.org/topic_2269",
"label": "Statistics and probability",
"synonyms": [
"Biostatistics",
"Multivariate statistics",
"Bayesian methods",
"Gaussian processes",
"Probability",
"Markov processes",
"Probabilistic graphical model",
"Inferential statistics",
"Descriptive statistics",
"Statistics"
],
"description": "The application of statistical methods to biological problems."
},
{
"id": 15,
"uri": "http://edamontology.org/topic_3517",
"label": "GWAS study",
"synonyms": [
"GWAS",
"Genome-wide association study",
"GWAS analysis"
],
"description": "Genome-wide association study experiments."
},
{
"id": 16,
"uri": "http://edamontology.org/topic_3316",
"label": "Computer science",
"synonyms": [
"Cloud computing",
"High performance computing",
"High-performance computing",
"HPC"
],
"description": "The theory and practical use of computer systems."
},
{
"id": 17,
"uri": "http://edamontology.org/topic_0605",
"label": "Informatics",
"synonyms": [
"Information science",
"Knowledge management",
"Information management"
],
"description": "The study and practice of information processing and use of computer information systems."
},
{
"id": 18,
"uri": "http://edamontology.org/topic_0092",
"label": "Data visualisation",
"synonyms": [
"Data rendering"
],
"description": "Rendering (drawing on a computer screen) or visualisation of molecular sequences, structures or other biomolecular data."
},
{
"id": 19,
"uri": "http://edamontology.org/topic_3534",
"label": "Protein binding sites",
"synonyms": [
"Protein key folding sites",
"Protein cleavage sites",
"Enzyme active site",
"Protein-nucleic acid binding sites",
"Protein functional sites"
],
"description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
},
{
"id": 20,
"uri": "http://edamontology.org/topic_0154",
"label": "Small molecules",
"synonyms": [
"Peptides and amino acids",
"Toxins and targets",
"Drugs and target structures",
"Drug targets",
"Peptides",
"Drug structures",
"Metabolite structures",
"Amino acids",
"Toxins",
"Targets",
"Chemical structures",
"Target structures"
],
"description": "Small molecules of biological significance, typically archival, curation, processing and analysis of structural information."
}
]
}