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            "id": 79,
            "uri": "http://edamontology.org/topic_2259",
            "label": "Systems biology",
            "synonyms": [
                "Biological system modelling",
                "Systems modelling",
                "Biological modelling"
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            "description": "The holistic modelling and analysis of complex biological systems and the interactions therein."
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            "id": 58,
            "uri": "http://edamontology.org/topic_2229",
            "label": "Cell biology",
            "synonyms": [
                "Protein subcellular localization",
                "Cellular processes",
                "Cells"
            ],
            "description": "Cells, such as key genes and proteins involved in the cell cycle."
        },
        {
            "id": 114,
            "uri": "http://edamontology.org/topic_1775",
            "label": "Function analysis",
            "synonyms": [
                "Protein function analysis",
                "Protein function prediction",
                "Functional analysis"
            ],
            "description": "The study of gene and protein function including the prediction of functional properties of a protein."
        },
        {
            "id": 33,
            "uri": "http://edamontology.org/topic_1317",
            "label": "Structural biology",
            "synonyms": [
                "Structural determination",
                "Structural assignment",
                "Structure determination"
            ],
            "description": "The molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids."
        },
        {
            "id": 110,
            "uri": "http://edamontology.org/topic_0804",
            "label": "Immunology",
            "synonyms": null,
            "description": "The application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on."
        },
        {
            "id": 3,
            "uri": "http://edamontology.org/topic_0798",
            "label": "Mobile genetic elements",
            "synonyms": [
                "Transposons"
            ],
            "description": "Mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns."
        },
        {
            "id": 81,
            "uri": "http://edamontology.org/topic_0797",
            "label": "Comparative genomics",
            "synonyms": null,
            "description": "The study (typically comparison) of the sequence, structure or function of multiple genomes."
        },
        {
            "id": 90,
            "uri": "http://edamontology.org/topic_0781",
            "label": "Virology",
            "synonyms": null,
            "description": "Study of viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation."
        },
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            "id": 86,
            "uri": "http://edamontology.org/topic_0780",
            "label": "Plant biology",
            "synonyms": [
                "Plant",
                "Plant physiology",
                "Plant anatomy",
                "Plant ecology",
                "Plant genetics",
                "Botany",
                "Plant science",
                "Plants",
                "Plant cell biology"
            ],
            "description": "Plants, e.g. information on a specific plant genome including molecular sequences, genes and annotation."
        },
        {
            "id": 49,
            "uri": "http://edamontology.org/topic_0769",
            "label": "Workflows",
            "synonyms": [
                "Software integration",
                "Pipelines",
                "Tool interoperability",
                "Tool integration"
            ],
            "description": "Biological or biomedical analytical workflows or pipelines."
        },
        {
            "id": 65,
            "uri": "http://edamontology.org/topic_0749",
            "label": "Transcription factors and regulatory sites",
            "synonyms": [
                "Attenuators",
                "Transcription factors",
                "GC signals",
                "Terminators",
                "-10 signals",
                "TFBS",
                "Isochores",
                "-35 signals",
                "Promoters",
                "Enhancers",
                "Transcriptional regulatory sites",
                "TATA signals",
                "CCAAT box",
                "Transcription factor binding sites",
                "CAAT signals",
                "CAT box",
                "CpG islands"
            ],
            "description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
        },
        {
            "id": 99,
            "uri": "http://edamontology.org/topic_0736",
            "label": "Protein folds and structural domains",
            "synonyms": [
                "Protein domains",
                "Protein membrane regions",
                "Protein folds",
                "Protein transmembrane regions",
                "Protein topological domains",
                "Protein structural domains",
                "Intramembrane regions",
                "Transmembrane regions"
            ],
            "description": "Protein tertiary structural domains and folds in a protein or polypeptide chain."
        },
        {
            "id": 103,
            "uri": "http://edamontology.org/topic_0659",
            "label": "Functional, regulatory and non-coding RNA",
            "synonyms": [
                "lncRNA",
                "Small ncRNA",
                "Small interfering RNA",
                "Small nuclear RNA",
                "siRNA",
                "ncRNA",
                "snRNA",
                "snoRNA",
                "Long non-coding RNA",
                "Functional RNA",
                "piwi-interacting RNA",
                "piRNA",
                "Long ncRNA",
                "microRNA",
                "miRNA",
                "Small nucleolar RNA",
                "Small and long non-coding RNAs",
                "Non-coding RNA",
                "Small non-coding RNA",
                "Regulatory RNA"
            ],
            "description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
        },
        {
            "id": 40,
            "uri": "http://edamontology.org/topic_0654",
            "label": "DNA",
            "synonyms": [
                "Ancient DNA",
                "DNA analysis",
                "Chromosomes"
            ],
            "description": "DNA sequences and structure, including processes such as methylation and replication."
        },
        {
            "id": 9,
            "uri": "http://edamontology.org/topic_0637",
            "label": "Taxonomy",
            "synonyms": null,
            "description": "Organism classification, identification and naming."
        },
        {
            "id": 96,
            "uri": "http://edamontology.org/topic_0634",
            "label": "Pathology",
            "synonyms": [
                "Pathology",
                "Disease"
            ],
            "description": "Diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases."
        },
        {
            "id": 97,
            "uri": "http://edamontology.org/topic_0632",
            "label": "Probes and primers",
            "synonyms": [
                "Primers",
                "Primer quality",
                "Probes"
            ],
            "description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
        },
        {
            "id": 62,
            "uri": "http://edamontology.org/topic_0625",
            "label": "Genotype and phenotype",
            "synonyms": [
                "Phenotype",
                "Genotyping",
                "Genotype-phenotype analysis",
                "Phenotyping",
                "Genotype",
                "Genotype and phenotype resources",
                "Genotype-phenotype"
            ],
            "description": "The study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on."
        },
        {
            "id": 70,
            "uri": "http://edamontology.org/topic_0623",
            "label": "Gene and protein families",
            "synonyms": [
                "Gene system",
                "Gene families",
                "Gene family",
                "Protein sequence classification",
                "Protein families",
                "Genes, gene family or system"
            ],
            "description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
        },
        {
            "id": 72,
            "uri": "http://edamontology.org/topic_0622",
            "label": "Genomics",
            "synonyms": [
                "Exomes",
                "Synthetic genomics",
                "Genome annotation",
                "Whole genomes",
                "Personal genomics",
                "Genomes",
                "Viral genomics"
            ],
            "description": "Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."
        }
    ]
}