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{
"id": 126,
"uri": "http://edamontology.org/topic_3474",
"label": "Machine learning",
"synonyms": [
"Kernel methods",
"Active learning",
"Supervised learning",
"Neural networks",
"Knowledge representation",
"Reinforcement learning",
"Ensembl learning",
"Unsupervised learning",
"Recommender system"
],
"description": "A topic concerning the application of artificial intelligence methods to algorithms, in order to create methods that can learn from data in order to generate an ouput, rather than relying on explicitly encoded information only."
},
{
"id": 17,
"uri": "http://edamontology.org/topic_0605",
"label": "Informatics",
"synonyms": [
"Information science",
"Knowledge management",
"Information management"
],
"description": "The study and practice of information processing and use of computer information systems."
},
{
"id": 36,
"uri": "http://edamontology.org/topic_3930",
"label": "Immunogenetics",
"synonyms": [
"Immune system genetics",
"Immunology and genetics",
"Immunogenes",
"Immungenetics"
],
"description": "A biomedical field that bridges immunology and genetics, to study the genetic basis of the immune system."
},
{
"id": 11,
"uri": "http://edamontology.org/topic_2815",
"label": "Human biology",
"synonyms": [
"Humans"
],
"description": "The study of human beings in general, including the human genome and proteome."
},
{
"id": 15,
"uri": "http://edamontology.org/topic_3517",
"label": "GWAS study",
"synonyms": [
"GWAS",
"Genome-wide association study",
"GWAS analysis"
],
"description": "Genome-wide association study experiments."
},
{
"id": 119,
"uri": "http://edamontology.org/topic_3292",
"label": "Biochemistry",
"synonyms": [
"Glycomics",
"Phytochemistry",
"Biological chemistry",
"Pathobiochemistry"
],
"description": "Chemical substances and physico-chemical processes and that occur within living organisms."
},
{
"id": 70,
"uri": "http://edamontology.org/topic_0623",
"label": "Gene and protein families",
"synonyms": [
"Gene system",
"Gene families",
"Gene family",
"Protein sequence classification",
"Protein families",
"Genes, gene family or system"
],
"description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
},
{
"id": 63,
"uri": "http://edamontology.org/topic_3053",
"label": "Genetics",
"synonyms": [
"Genes",
"Heredity"
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"description": "The study of genes, genetic variation and heredity in living organisms."
},
{
"id": 117,
"uri": "http://edamontology.org/topic_0114",
"label": "Gene structure",
"synonyms": [
"Fusion genes",
"Gene features"
],
"description": "Gene structure, regions which make an RNA product and features such as promoters, coding regions, gene fusion, splice sites etc."
},
{
"id": 26,
"uri": "http://edamontology.org/topic_3512",
"label": "Gene transcripts",
"synonyms": [
"Exons",
"Introns",
"PolyA site",
"EST",
"Gene transcript features",
"Transit peptide coding sequence",
"mRNA",
"Fusion transcripts",
"Coding RNA",
"PolyA signal",
"mRNA features",
"cDNA",
"Signal peptide coding sequence"
],
"description": "Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."
},
{
"id": 64,
"uri": "http://edamontology.org/topic_3172",
"label": "Metabolomics",
"synonyms": [
"Exometabolomics",
"Metabolites",
"Metabonomics",
"MS-based metabolomics",
"MS-based untargeted metabolomics",
"NMR-based metabolomics",
"Metabolome",
"LC-MS-based metabolomics",
"MS-based targeted metabolomics",
"Mass spectrometry-based metabolomics"
],
"description": "The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism."
},
{
"id": 72,
"uri": "http://edamontology.org/topic_0622",
"label": "Genomics",
"synonyms": [
"Exomes",
"Synthetic genomics",
"Genome annotation",
"Whole genomes",
"Personal genomics",
"Genomes",
"Viral genomics"
],
"description": "Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."
},
{
"id": 123,
"uri": "http://edamontology.org/topic_3676",
"label": "Exome sequencing",
"synonyms": [
"Exome",
"Exome capture",
"WES",
"Whole exome sequencing",
"Targeted exome capture",
"Exome analysis"
],
"description": "Laboratory technique to sequence all the protein-coding regions in a genome, i.e., the exome."
},
{
"id": 71,
"uri": "http://edamontology.org/topic_3299",
"label": "Evolutionary biology",
"synonyms": [
"Evolution"
],
"description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
},
{
"id": 131,
"uri": "http://edamontology.org/topic_3305",
"label": "Public health and epidemiology",
"synonyms": [
"Epidemiology",
"Public health"
],
"description": "Topic concerning the the patterns, cause, and effect of disease within populations."
},
{
"id": 125,
"uri": "http://edamontology.org/topic_3407",
"label": "Endocrinology and metabolism",
"synonyms": [
"Endocrine disorders",
"Metabolism",
"Endocrinology",
"Metabolic disorders"
],
"description": "The branch of medicine dealing with diseases of endocrine organs, hormone systems, their target organs, and disorders of the pathways of glucose and lipid metabolism."
},
{
"id": 136,
"uri": "http://edamontology.org/topic_3300",
"label": "Physiology",
"synonyms": [
"Electrophysiology"
],
"description": "The functions of living organisms and their constituent parts."
},
{
"id": 85,
"uri": "http://edamontology.org/topic_0610",
"label": "Ecology",
"synonyms": [
"Ecological informatics",
"Ecoinformatics",
"Ecosystem science",
"Computational ecology"
],
"description": "The ecological and environmental sciences and especially the application of information technology (ecoinformatics)."
},
{
"id": 93,
"uri": "http://edamontology.org/topic_0199",
"label": "Genetic variation",
"synonyms": [
"DNA variation",
"Somatic mutations",
"Genomic variation",
"Mutation",
"Polymorphism"
],
"description": "Stable, naturally occuring mutations in a nucleotide sequence including alleles, naturally occurring mutations such as single base nucleotide substitutions, deletions and insertions, RFLPs and other polymorphisms."
},
{
"id": 39,
"uri": "http://edamontology.org/topic_0097",
"label": "Nucleic acid structure analysis",
"synonyms": [
"DNA structure",
"Nucleic acid structure",
"Nucleic acid denaturation",
"DNA melting",
"RNA structure alignment",
"RNA structure",
"Nucleic acid thermodynamics",
"RNA alignment"
],
"description": "The archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation."
}
]
}