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{
    "count": 127,
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        {
            "id": 62,
            "uri": "http://edamontology.org/topic_0625",
            "label": "Genotype and phenotype",
            "synonyms": [
                "Phenotype",
                "Genotyping",
                "Genotype-phenotype analysis",
                "Phenotyping",
                "Genotype",
                "Genotype and phenotype resources",
                "Genotype-phenotype"
            ],
            "description": "The study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on."
        },
        {
            "id": 72,
            "uri": "http://edamontology.org/topic_0622",
            "label": "Genomics",
            "synonyms": [
                "Exomes",
                "Synthetic genomics",
                "Genome annotation",
                "Whole genomes",
                "Personal genomics",
                "Genomes",
                "Viral genomics"
            ],
            "description": "Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."
        },
        {
            "id": 26,
            "uri": "http://edamontology.org/topic_3512",
            "label": "Gene transcripts",
            "synonyms": [
                "Exons",
                "Introns",
                "PolyA site",
                "EST",
                "Gene transcript features",
                "Transit peptide coding sequence",
                "mRNA",
                "Fusion transcripts",
                "Coding RNA",
                "PolyA signal",
                "mRNA features",
                "cDNA",
                "Signal peptide coding sequence"
            ],
            "description": "Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."
        },
        {
            "id": 93,
            "uri": "http://edamontology.org/topic_0199",
            "label": "Genetic variation",
            "synonyms": [
                "DNA variation",
                "Somatic mutations",
                "Genomic variation",
                "Mutation",
                "Polymorphism"
            ],
            "description": "Stable, naturally occuring mutations in a nucleotide sequence including alleles, naturally occurring mutations such as single base nucleotide substitutions, deletions and insertions, RFLPs and other polymorphisms."
        },
        {
            "id": 63,
            "uri": "http://edamontology.org/topic_3053",
            "label": "Genetics",
            "synonyms": [
                "Genes",
                "Heredity"
            ],
            "description": "The study of genes, genetic variation and heredity in living organisms."
        },
        {
            "id": 117,
            "uri": "http://edamontology.org/topic_0114",
            "label": "Gene structure",
            "synonyms": [
                "Fusion genes",
                "Gene features"
            ],
            "description": "Gene structure, regions which make an RNA product and features such as promoters, coding regions, gene fusion, splice sites etc."
        },
        {
            "id": 73,
            "uri": "http://edamontology.org/topic_0204",
            "label": "Gene regulation",
            "synonyms": [
                "Regulatory genomics"
            ],
            "description": "The regulation of gene expression."
        },
        {
            "id": 27,
            "uri": "http://edamontology.org/topic_0203",
            "label": "Gene expression",
            "synonyms": [
                "DNA chips",
                "DNA microarrays",
                "Gene translation",
                "Transcription",
                "Expression",
                "Gene expression profiling",
                "Codon usage",
                "Gene transcription"
            ],
            "description": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data."
        },
        {
            "id": 70,
            "uri": "http://edamontology.org/topic_0623",
            "label": "Gene and protein families",
            "synonyms": [
                "Gene system",
                "Gene families",
                "Gene family",
                "Protein sequence classification",
                "Protein families",
                "Genes, gene family or system"
            ],
            "description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
        },
        {
            "id": 114,
            "uri": "http://edamontology.org/topic_1775",
            "label": "Function analysis",
            "synonyms": [
                "Protein function analysis",
                "Protein function prediction",
                "Functional analysis"
            ],
            "description": "The study of gene and protein function including the prediction of functional properties of a protein."
        },
        {
            "id": 103,
            "uri": "http://edamontology.org/topic_0659",
            "label": "Functional, regulatory and non-coding RNA",
            "synonyms": [
                "lncRNA",
                "Small ncRNA",
                "Small interfering RNA",
                "Small nuclear RNA",
                "siRNA",
                "ncRNA",
                "snRNA",
                "snoRNA",
                "Long non-coding RNA",
                "Functional RNA",
                "piwi-interacting RNA",
                "piRNA",
                "Long ncRNA",
                "microRNA",
                "miRNA",
                "Small nucleolar RNA",
                "Small and long non-coding RNAs",
                "Non-coding RNA",
                "Small non-coding RNA",
                "Regulatory RNA"
            ],
            "description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
        },
        {
            "id": 82,
            "uri": "http://edamontology.org/topic_0085",
            "label": "Functional genomics",
            "synonyms": null,
            "description": "The study of gene or protein functions and their interactions in totality in a given organism, tissue, cell etc."
        },
        {
            "id": 109,
            "uri": "http://edamontology.org/topic_3678",
            "label": "Experimental design and studies",
            "synonyms": [
                "Studies",
                "Experimental design",
                "Design of experiments"
            ],
            "description": "The design of an experiment intended to test a hypothesis, and describe or explain empirical data obtained under various experimental conditions."
        },
        {
            "id": 123,
            "uri": "http://edamontology.org/topic_3676",
            "label": "Exome sequencing",
            "synonyms": [
                "Exome",
                "Exome capture",
                "WES",
                "Whole exome sequencing",
                "Targeted exome capture",
                "Exome analysis"
            ],
            "description": "Laboratory technique to sequence all the protein-coding regions in a genome, i.e., the exome."
        },
        {
            "id": 71,
            "uri": "http://edamontology.org/topic_3299",
            "label": "Evolutionary biology",
            "synonyms": [
                "Evolution"
            ],
            "description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
        },
        {
            "id": 125,
            "uri": "http://edamontology.org/topic_3407",
            "label": "Endocrinology and metabolism",
            "synonyms": [
                "Endocrine disorders",
                "Metabolism",
                "Endocrinology",
                "Metabolic disorders"
            ],
            "description": "The branch of medicine dealing with diseases of endocrine organs, hormone systems, their target organs, and disorders of the pathways of glucose and lipid metabolism."
        },
        {
            "id": 54,
            "uri": "http://edamontology.org/topic_3065",
            "label": "Embryology",
            "synonyms": null,
            "description": "The development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage."
        },
        {
            "id": 85,
            "uri": "http://edamontology.org/topic_0610",
            "label": "Ecology",
            "synonyms": [
                "Ecological informatics",
                "Ecoinformatics",
                "Ecosystem science",
                "Computational ecology"
            ],
            "description": "The ecological and environmental sciences and especially the application of information technology (ecoinformatics)."
        },
        {
            "id": 4,
            "uri": "http://edamontology.org/topic_2885",
            "label": "DNA polymorphism",
            "synonyms": [
                "Microsatellites",
                "SNP",
                "Variable number of tandem repeat polymorphism",
                "snps",
                "Single nucleotide polymorphism",
                "VNTR",
                "RFLP"
            ],
            "description": "DNA polymorphism."
        },
        {
            "id": 25,
            "uri": "http://edamontology.org/topic_3125",
            "label": "DNA binding sites",
            "synonyms": [
                "Matrix-attachment region",
                "Ribosome binding sites",
                "Scaffold-attachment region",
                "Matrix/scaffold attachment region",
                "Nucleosome exclusion sequences",
                "Restriction sites"
            ],
            "description": "Nucleic acids binding to some other molecule."
        }
    ]
}