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{
"count": 128,
"next": "https://catalogue.france-bioinformatique.fr/api/topic/?format=api&limit=20&offset=100",
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"results": [
{
"id": 25,
"uri": "http://edamontology.org/topic_3125",
"label": "DNA binding sites",
"synonyms": [
"Matrix-attachment region",
"Ribosome binding sites",
"Scaffold-attachment region",
"Matrix/scaffold attachment region",
"Nucleosome exclusion sequences",
"Restriction sites"
],
"description": "Nucleic acids binding to some other molecule."
},
{
"id": 30,
"uri": "http://edamontology.org/topic_2275",
"label": "Molecular modelling",
"synonyms": [
"Comparative modelling",
"Homology modeling",
"Docking",
"Homology modelling",
"Molecular docking"
],
"description": "The construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour, including the modelling the structure of proteins in complex with small molecules or other macromolecules (docking)."
},
{
"id": 105,
"uri": "http://edamontology.org/topic_3169",
"label": "ChIP-seq",
"synonyms": [
"ChIP-sequencing",
"Chip sequencing",
"Chip Seq",
"ChIP-exo",
"Chip-sequencing"
],
"description": "The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."
},
{
"id": 81,
"uri": "http://edamontology.org/topic_0797",
"label": "Comparative genomics",
"synonyms": null,
"description": "The study (typically comparison) of the sequence, structure or function of multiple genomes."
},
{
"id": 18,
"uri": "http://edamontology.org/topic_0092",
"label": "Data visualisation",
"synonyms": [
"Data rendering"
],
"description": "Rendering (drawing on a computer screen) or visualisation of molecular sequences, structures or other biomolecular data."
},
{
"id": 50,
"uri": "http://edamontology.org/topic_3510",
"label": "Protein sites, features and motifs",
"synonyms": [
"Protein sequence features",
"Signal peptide cleavage sites"
],
"description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in protein sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 72,
"uri": "http://edamontology.org/topic_0622",
"label": "Genomics",
"synonyms": [
"Exomes",
"Synthetic genomics",
"Genome annotation",
"Whole genomes",
"Personal genomics",
"Genomes",
"Viral genomics"
],
"description": "Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."
},
{
"id": 59,
"uri": "http://edamontology.org/topic_3293",
"label": "Phylogenetics",
"synonyms": null,
"description": "The study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences)."
},
{
"id": 73,
"uri": "http://edamontology.org/topic_0204",
"label": "Gene regulation",
"synonyms": [
"Regulatory genomics"
],
"description": "The regulation of gene expression."
},
{
"id": 22,
"uri": "http://edamontology.org/topic_0196",
"label": "Sequence assembly",
"synonyms": [
"Assembly"
],
"description": "The assembly of fragments of a DNA sequence to reconstruct the original sequence."
},
{
"id": 14,
"uri": "http://edamontology.org/topic_2269",
"label": "Statistics and probability",
"synonyms": [
"Biostatistics",
"Multivariate statistics",
"Bayesian methods",
"Gaussian processes",
"Probability",
"Markov processes",
"Probabilistic graphical model",
"Inferential statistics",
"Descriptive statistics",
"Statistics"
],
"description": "The application of statistical methods to biological problems."
},
{
"id": 51,
"uri": "http://edamontology.org/topic_3308",
"label": "Transcriptomics",
"synonyms": [
"Transcriptome",
"Comparative transcriptomics",
"Metatranscriptomics"
],
"description": "The analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc."
},
{
"id": 70,
"uri": "http://edamontology.org/topic_0623",
"label": "Gene and protein families",
"synonyms": [
"Gene system",
"Gene families",
"Gene family",
"Protein sequence classification",
"Protein families",
"Genes, gene family or system"
],
"description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
},
{
"id": 9,
"uri": "http://edamontology.org/topic_0637",
"label": "Taxonomy",
"synonyms": null,
"description": "Organism classification, identification and naming."
},
{
"id": 13,
"uri": "http://edamontology.org/topic_3170",
"label": "RNA-Seq",
"synonyms": [
"RNA sequencing",
"RNA-Seq analysis",
"Whole transcriptome shotgun sequencing",
"WTSS",
"Small-Seq",
"Small RNA sequencing",
"Small RNA-Seq",
"miRNA-seq",
"MicroRNA sequencing",
"Transcriptome profiling"
],
"description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
},
{
"id": 28,
"uri": "http://edamontology.org/topic_0081",
"label": "Structure analysis",
"synonyms": [
"Structural bioinformatics",
"Computational structural biology",
"Structure data resources",
"Molecular structure",
"Structures",
"Structure databases",
"Biomolecular structure"
],
"description": "The curation, processing, analysis and prediction of data about the structure of biological molecules, typically proteins and nucleic acids and other macromolecules."
},
{
"id": 96,
"uri": "http://edamontology.org/topic_0634",
"label": "Pathology",
"synonyms": [
"Pathology",
"Disease"
],
"description": "Diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases."
},
{
"id": 113,
"uri": "http://edamontology.org/topic_2814",
"label": "Protein structure analysis",
"synonyms": [
"Protein tertiary structure",
"Protein structure"
],
"description": "Protein secondary or tertiary structural data and/or associated annotation."
},
{
"id": 74,
"uri": "http://edamontology.org/topic_0078",
"label": "Proteins",
"synonyms": [
"Protein informatics",
"Protein bioinformatics",
"Protein databases"
],
"description": "Archival, processing and analysis of protein data, typically molecular sequence and structural data."
},
{
"id": 26,
"uri": "http://edamontology.org/topic_3512",
"label": "Gene transcripts",
"synonyms": [
"Exons",
"Introns",
"PolyA site",
"EST",
"Gene transcript features",
"Transit peptide coding sequence",
"mRNA",
"Fusion transcripts",
"Coding RNA",
"PolyA signal",
"mRNA features",
"cDNA",
"Signal peptide coding sequence"
],
"description": "Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."
}
]
}