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            "id": 118,
            "uri": "http://edamontology.org/topic_0099",
            "label": "RNA",
            "synonyms": [
                "Small RNA"
            ],
            "description": "RNA sequences and structures."
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            "id": 92,
            "uri": "http://edamontology.org/topic_3320",
            "label": "RNA splicing",
            "synonyms": [
                "Alternative splicing",
                "Splice sites"
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            "description": "RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons."
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        {
            "id": 28,
            "uri": "http://edamontology.org/topic_0081",
            "label": "Structure analysis",
            "synonyms": [
                "Structural bioinformatics",
                "Computational structural biology",
                "Structure data resources",
                "Molecular structure",
                "Structures",
                "Structure databases",
                "Biomolecular structure"
            ],
            "description": "The curation, processing, analysis and prediction of data about the structure of biological molecules, typically proteins and nucleic acids and other macromolecules."
        },
        {
            "id": 27,
            "uri": "http://edamontology.org/topic_0203",
            "label": "Gene expression",
            "synonyms": [
                "DNA chips",
                "DNA microarrays",
                "Gene translation",
                "Transcription",
                "Expression",
                "Gene expression profiling",
                "Codon usage",
                "Gene transcription"
            ],
            "description": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data."
        },
        {
            "id": 73,
            "uri": "http://edamontology.org/topic_0204",
            "label": "Gene regulation",
            "synonyms": [
                "Regulatory genomics"
            ],
            "description": "The regulation of gene expression."
        },
        {
            "id": 25,
            "uri": "http://edamontology.org/topic_3125",
            "label": "DNA binding sites",
            "synonyms": [
                "Matrix-attachment region",
                "Ribosome binding sites",
                "Scaffold-attachment region",
                "Matrix/scaffold attachment region",
                "Nucleosome exclusion sequences",
                "Restriction sites"
            ],
            "description": "Nucleic acids binding to some other molecule."
        },
        {
            "id": 78,
            "uri": "http://edamontology.org/topic_0219",
            "label": "Data submission, annotation and curation",
            "synonyms": [
                "Database curation",
                "Data curation",
                "Data provenance"
            ],
            "description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
        },
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            "id": 35,
            "uri": "http://edamontology.org/topic_0160",
            "label": "Sequence sites, features and motifs",
            "synonyms": [
                "Sequence profiles",
                "Sequence sites",
                "Sequence motifs",
                "HMMs",
                "Functional sites",
                "Sequence features"
            ],
            "description": "The archival, detection, prediction and analysis of positional features such as functional and other key sites, in molecular sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
        },
        {
            "id": 105,
            "uri": "http://edamontology.org/topic_3169",
            "label": "ChIP-seq",
            "synonyms": [
                "ChIP-sequencing",
                "Chip sequencing",
                "Chip Seq",
                "ChIP-exo",
                "Chip-sequencing"
            ],
            "description": "The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."
        },
        {
            "id": 59,
            "uri": "http://edamontology.org/topic_3293",
            "label": "Phylogenetics",
            "synonyms": null,
            "description": "The study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences)."
        },
        {
            "id": 18,
            "uri": "http://edamontology.org/topic_0092",
            "label": "Data visualisation",
            "synonyms": [
                "Data rendering"
            ],
            "description": "Rendering (drawing on a computer screen) or visualisation of molecular sequences, structures or other biomolecular data."
        },
        {
            "id": 45,
            "uri": "http://edamontology.org/topic_3174",
            "label": "Metagenomics",
            "synonyms": [
                "Biome sequencing",
                "Shotgun metagenomics"
            ],
            "description": "The study of genetic material recovered from environmental samples, and associated environmental data."
        },
        {
            "id": 7,
            "uri": "http://edamontology.org/topic_3489",
            "label": "Database management",
            "synonyms": [
                "Content management",
                "Document, record and content management",
                "Record management",
                "Data maintenance",
                "File management",
                "Database administration",
                "Document management"
            ],
            "description": "The general handling of data stored in digital archives such as databanks, databases proper, web portals and other data resources."
        },
        {
            "id": 120,
            "uri": "http://edamontology.org/topic_2840",
            "label": "Toxicology",
            "synonyms": [
                "Toxicoinformatics",
                "Computational toxicology"
            ],
            "description": "Toxins and the adverse effects of these chemical substances on living organisms."
        },
        {
            "id": 95,
            "uri": "http://edamontology.org/topic_3574",
            "label": "Human genetics",
            "synonyms": null,
            "description": "The study of inheritance in human beings."
        },
        {
            "id": 113,
            "uri": "http://edamontology.org/topic_2814",
            "label": "Protein structure analysis",
            "synonyms": [
                "Protein tertiary structure",
                "Protein structure"
            ],
            "description": "Protein secondary or tertiary structural data and/or associated annotation."
        },
        {
            "id": 40,
            "uri": "http://edamontology.org/topic_0654",
            "label": "DNA",
            "synonyms": [
                "Ancient DNA",
                "DNA analysis",
                "Chromosomes"
            ],
            "description": "DNA sequences and structure, including processes such as methylation and replication."
        },
        {
            "id": 110,
            "uri": "http://edamontology.org/topic_0804",
            "label": "Immunology",
            "synonyms": null,
            "description": "The application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on."
        },
        {
            "id": 26,
            "uri": "http://edamontology.org/topic_3512",
            "label": "Gene transcripts",
            "synonyms": [
                "Exons",
                "Introns",
                "PolyA site",
                "EST",
                "Gene transcript features",
                "Transit peptide coding sequence",
                "mRNA",
                "Fusion transcripts",
                "Coding RNA",
                "PolyA signal",
                "mRNA features",
                "cDNA",
                "Signal peptide coding sequence"
            ],
            "description": "Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."
        },
        {
            "id": 38,
            "uri": "http://edamontology.org/topic_0080",
            "label": "Sequence analysis",
            "synonyms": [
                "Sequences",
                "Biological sequences",
                "Sequence databases"
            ],
            "description": "The archival, processing and analysis of molecular sequences (monomer composition of polymers) including molecular sequence data resources, sequence sites, alignments, motifs and profiles."
        }
    ]
}