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"id": 63,
"uri": "http://edamontology.org/topic_3053",
"label": "Genetics",
"synonyms": [
"Genes",
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"description": "The study of genes, genetic variation and heredity in living organisms."
},
{
"id": 102,
"uri": "http://edamontology.org/topic_3056",
"label": "Population genetics",
"synonyms": null,
"description": "The distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow."
},
{
"id": 61,
"uri": "http://edamontology.org/topic_3063",
"label": "Medical informatics",
"synonyms": [
"Biomedical informatics",
"Health and disease",
"Clinical informatics",
"Healthcare informatics",
"Health informatics"
],
"description": "The application of information technology to health, disease and biomedicine."
},
{
"id": 57,
"uri": "http://edamontology.org/topic_3064",
"label": "Developmental biology",
"synonyms": [
"Development"
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"description": "How organisms grow and develop."
},
{
"id": 54,
"uri": "http://edamontology.org/topic_3065",
"label": "Embryology",
"synonyms": null,
"description": "The development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage."
},
{
"id": 100,
"uri": "http://edamontology.org/topic_3068",
"label": "Literature and language",
"synonyms": [
"Scientific literature",
"Literature",
"Language",
"References",
"Documentation",
"Citations",
"Bibliography"
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"description": "The scientific literature, language processing, reference information, and documentation."
},
{
"id": 87,
"uri": "http://edamontology.org/topic_3071",
"label": "Biological databases",
"synonyms": [
"Data management",
"Databases and information systems",
"Information systems"
],
"description": "The development and use of architectures, policies, practices and procedures for management of data."
},
{
"id": 8,
"uri": "http://edamontology.org/topic_3077",
"label": "Data acquisition",
"synonyms": [
"Data collection"
],
"description": "The acquisition of data, typically measurements of physical systems using any type of sampling system, or by another other means."
},
{
"id": 25,
"uri": "http://edamontology.org/topic_3125",
"label": "DNA binding sites",
"synonyms": [
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"Ribosome binding sites",
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"Nucleosome exclusion sequences",
"Restriction sites"
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"description": "Nucleic acids binding to some other molecule."
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{
"id": 23,
"uri": "http://edamontology.org/topic_3168",
"label": "Sequencing",
"synonyms": [
"Panels",
"Primer walking",
"DNA-Seq",
"High-throughput sequencing",
"Chromosome walking",
"Next generation sequencing",
"NGS data analysis",
"Next gen sequencing",
"High throughput sequencing",
"Targeted next-generation sequencing panels",
"NGS",
"Sanger sequencing",
"Clone verification",
"DNase-Seq"
],
"description": "The determination of complete (typically nucleotide) sequences, including those of genomes (full genome sequencing, de novo sequencing and resequencing), amplicons and transcriptomes."
},
{
"id": 105,
"uri": "http://edamontology.org/topic_3169",
"label": "ChIP-seq",
"synonyms": [
"ChIP-sequencing",
"Chip sequencing",
"Chip Seq",
"ChIP-exo",
"Chip-sequencing"
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"description": "The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."
},
{
"id": 13,
"uri": "http://edamontology.org/topic_3170",
"label": "RNA-Seq",
"synonyms": [
"RNA sequencing",
"RNA-Seq analysis",
"Whole transcriptome shotgun sequencing",
"WTSS",
"Small-Seq",
"Small RNA sequencing",
"Small RNA-Seq",
"miRNA-seq",
"MicroRNA sequencing",
"Transcriptome profiling"
],
"description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
},
{
"id": 64,
"uri": "http://edamontology.org/topic_3172",
"label": "Metabolomics",
"synonyms": [
"Exometabolomics",
"Metabolites",
"Metabonomics",
"MS-based metabolomics",
"MS-based untargeted metabolomics",
"NMR-based metabolomics",
"Metabolome",
"LC-MS-based metabolomics",
"MS-based targeted metabolomics",
"Mass spectrometry-based metabolomics"
],
"description": "The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism."
},
{
"id": 45,
"uri": "http://edamontology.org/topic_3174",
"label": "Metagenomics",
"synonyms": [
"Biome sequencing",
"Shotgun metagenomics"
],
"description": "The study of genetic material recovered from environmental samples, and associated environmental data."
},
{
"id": 119,
"uri": "http://edamontology.org/topic_3292",
"label": "Biochemistry",
"synonyms": [
"Glycomics",
"Phytochemistry",
"Biological chemistry",
"Pathobiochemistry"
],
"description": "Chemical substances and physico-chemical processes and that occur within living organisms."
},
{
"id": 59,
"uri": "http://edamontology.org/topic_3293",
"label": "Phylogenetics",
"synonyms": null,
"description": "The study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences)."
},
{
"id": 48,
"uri": "http://edamontology.org/topic_3298",
"label": "Phenomics",
"synonyms": null,
"description": "Phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors."
},
{
"id": 71,
"uri": "http://edamontology.org/topic_3299",
"label": "Evolutionary biology",
"synonyms": [
"Evolution"
],
"description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
},
{
"id": 83,
"uri": "http://edamontology.org/topic_3301",
"label": "Microbiology",
"synonyms": [
"Microbial physiology",
"Microbial genetics",
"Microbiological surveillance",
"Molecular microbiology",
"Medical microbiology",
"Antimicrobial stewardship",
"Microbial surveillance",
"Molecular infection biology"
],
"description": "The biology of microorganisms."
},
{
"id": 29,
"uri": "http://edamontology.org/topic_3306",
"label": "Biophysics",
"synonyms": [
"Medical physics"
],
"description": "The use of physics to study biological system."
}
]
}