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"id": 61,
"uri": "http://edamontology.org/topic_3063",
"label": "Medical informatics",
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"Biomedical informatics",
"Health and disease",
"Clinical informatics",
"Healthcare informatics",
"Health informatics"
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"description": "The application of information technology to health, disease and biomedicine."
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"id": 62,
"uri": "http://edamontology.org/topic_0625",
"label": "Genotype and phenotype",
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"Phenotype",
"Genotyping",
"Genotype-phenotype analysis",
"Phenotyping",
"Genotype",
"Genotype and phenotype resources",
"Genotype-phenotype"
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"description": "The study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on."
},
{
"id": 63,
"uri": "http://edamontology.org/topic_3053",
"label": "Genetics",
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{
"id": 64,
"uri": "http://edamontology.org/topic_3172",
"label": "Metabolomics",
"synonyms": [
"Exometabolomics",
"Metabolites",
"Metabonomics",
"MS-based metabolomics",
"MS-based untargeted metabolomics",
"NMR-based metabolomics",
"Metabolome",
"LC-MS-based metabolomics",
"MS-based targeted metabolomics",
"Mass spectrometry-based metabolomics"
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"description": "The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism."
},
{
"id": 65,
"uri": "http://edamontology.org/topic_0749",
"label": "Transcription factors and regulatory sites",
"synonyms": [
"Attenuators",
"Transcription factors",
"GC signals",
"Terminators",
"-10 signals",
"TFBS",
"Isochores",
"-35 signals",
"Promoters",
"Enhancers",
"Transcriptional regulatory sites",
"TATA signals",
"CCAAT box",
"Transcription factor binding sites",
"CAAT signals",
"CAT box",
"CpG islands"
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"description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
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{
"id": 66,
"uri": "http://edamontology.org/topic_3511",
"label": "Nucleic acid sites, features and motifs",
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"Primer binding sites",
"Nucleic acid sequence features",
"Sequence tagged sites"
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"description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in nucleic acid sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 67,
"uri": "http://edamontology.org/topic_3050",
"label": "Biodiversity",
"synonyms": null,
"description": "The degree of variation of life forms within a given ecosystem, biome or an entire planet."
},
{
"id": 68,
"uri": "http://edamontology.org/topic_0194",
"label": "Phylogenomics",
"synonyms": null,
"description": "The integrated study of evolutionary relationships and whole genome data, for example, in the analysis of species trees, horizontal gene transfer and evolutionary reconstruction."
},
{
"id": 69,
"uri": "http://edamontology.org/topic_3943",
"label": "Paleogenomics",
"synonyms": [
"Paleogenetics",
"Ancestral genomes"
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"description": "The reconstruction and analysis of genomic information in extinct species."
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"id": 70,
"uri": "http://edamontology.org/topic_0623",
"label": "Gene and protein families",
"synonyms": [
"Gene system",
"Gene families",
"Gene family",
"Protein sequence classification",
"Protein families",
"Genes, gene family or system"
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"description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
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{
"id": 71,
"uri": "http://edamontology.org/topic_3299",
"label": "Evolutionary biology",
"synonyms": [
"Evolution"
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"description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
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{
"id": 72,
"uri": "http://edamontology.org/topic_0622",
"label": "Genomics",
"synonyms": [
"Exomes",
"Synthetic genomics",
"Genome annotation",
"Whole genomes",
"Personal genomics",
"Genomes",
"Viral genomics"
],
"description": "Whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc."
},
{
"id": 73,
"uri": "http://edamontology.org/topic_0204",
"label": "Gene regulation",
"synonyms": [
"Regulatory genomics"
],
"description": "The regulation of gene expression."
},
{
"id": 74,
"uri": "http://edamontology.org/topic_0078",
"label": "Proteins",
"synonyms": [
"Protein informatics",
"Protein bioinformatics",
"Protein databases"
],
"description": "Archival, processing and analysis of protein data, typically molecular sequence and structural data."
},
{
"id": 75,
"uri": "http://edamontology.org/topic_3307",
"label": "Computational biology",
"synonyms": [
"Mathematical biology",
"Biomathematics",
"Theoretical biology"
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"description": "The development and application of theory, analytical methods, mathematical models and computational simulation of biological systems."
},
{
"id": 76,
"uri": "http://edamontology.org/topic_3332",
"label": "Computational chemistry",
"synonyms": null,
"description": "Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of chemical systems."
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{
"id": 77,
"uri": "http://edamontology.org/topic_0602",
"label": "Molecular interactions, pathways and networks",
"synonyms": [
"Networks",
"Gene regulatory networks",
"Interactome",
"Molecular interactions",
"Disease pathways",
"Biological pathways",
"Signaling pathways",
"Pathways",
"Environmental information processing pathways",
"Cellular process pathways",
"Genetic information processing pathways",
"Signal transduction pathways",
"Biological models",
"Metabolic pathways",
"Biological networks",
"Interactions"
],
"description": "Molecular interactions, biological pathways, networks and other models."
},
{
"id": 78,
"uri": "http://edamontology.org/topic_0219",
"label": "Data submission, annotation and curation",
"synonyms": [
"Database curation",
"Data curation",
"Data provenance"
],
"description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
},
{
"id": 79,
"uri": "http://edamontology.org/topic_2259",
"label": "Systems biology",
"synonyms": [
"Biological system modelling",
"Systems modelling",
"Biological modelling"
],
"description": "The holistic modelling and analysis of complex biological systems and the interactions therein."
},
{
"id": 80,
"uri": "http://edamontology.org/topic_0621",
"label": "Model organisms",
"synonyms": [
"Organisms"
],
"description": "A specific organism, or group of organisms, used to study a particular aspect of biology."
}
]
}