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"count": 127,
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{
"id": 98,
"uri": "http://edamontology.org/topic_3518",
"label": "Microarray experiment",
"synonyms": [
"miRNA array",
"Proprietary platform micoarray",
"MicroRNA array",
"Gene expression microarray",
"Multichannel microarray",
"RNA microarrays",
"Microarrays",
"mRNA microarray",
"Reverse phase protein array",
"One channel microarray",
"aCGH microarray",
"Tissue microarray",
"SNP array",
"Methylation array",
"Tiling arrays",
"RNA chips",
"Genotyping array",
"Two channel microarray"
],
"description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
},
{
"id": 20,
"uri": "http://edamontology.org/topic_0154",
"label": "Small molecules",
"synonyms": [
"Peptides and amino acids",
"Toxins and targets",
"Drugs and target structures",
"Drug targets",
"Peptides",
"Drug structures",
"Metabolite structures",
"Amino acids",
"Toxins",
"Targets",
"Chemical structures",
"Target structures"
],
"description": "Small molecules of biological significance, typically archival, curation, processing and analysis of structural information."
},
{
"id": 83,
"uri": "http://edamontology.org/topic_3301",
"label": "Microbiology",
"synonyms": [
"Microbial physiology",
"Microbial genetics",
"Microbiological surveillance",
"Molecular microbiology",
"Medical microbiology",
"Antimicrobial stewardship",
"Microbial surveillance",
"Molecular infection biology"
],
"description": "The biology of microorganisms."
},
{
"id": 41,
"uri": "http://edamontology.org/topic_0157",
"label": "Sequence composition, complexity and repeats",
"synonyms": [
"Protein sequence repeats",
"Sequence complexity",
"Low complexity sequences",
"Nucleic acid repeats",
"Repeat sequences",
"Sequence composition",
"Sequence repeats",
"Protein repeats"
],
"description": "The archival, processing and analysis of the basic character composition of molecular sequences, for example character or word frequency, ambiguity, complexity, particularly regions of low complexity, and repeats or the repetitive nature of molecular sequences."
},
{
"id": 39,
"uri": "http://edamontology.org/topic_0097",
"label": "Nucleic acid structure analysis",
"synonyms": [
"DNA structure",
"Nucleic acid structure",
"Nucleic acid denaturation",
"DNA melting",
"RNA structure alignment",
"RNA structure",
"Nucleic acid thermodynamics",
"RNA alignment"
],
"description": "The archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation."
},
{
"id": 112,
"uri": "http://edamontology.org/topic_3420",
"label": "Reproductive health",
"synonyms": [
"Andrology",
"Family planning",
"Reproductive_health",
"Reproductive disorders",
"Fertility medicine"
],
"description": "The health of the reproductive processes, functions and systems at all stages of life."
},
{
"id": 43,
"uri": "http://edamontology.org/topic_3321",
"label": "Molecular genetics",
"synonyms": null,
"description": "The structure and function of genes at a molecular level."
},
{
"id": 42,
"uri": "http://edamontology.org/topic_3366",
"label": "Data integration and warehousing",
"synonyms": [
"Data integration",
"Data warehousing"
],
"description": "The combination and integration of data from different sources, for example into a central repository or warehouse, to provide users with a unified view of these data."
},
{
"id": 103,
"uri": "http://edamontology.org/topic_0659",
"label": "Functional, regulatory and non-coding RNA",
"synonyms": [
"lncRNA",
"Small ncRNA",
"Small interfering RNA",
"Small nuclear RNA",
"siRNA",
"ncRNA",
"snRNA",
"snoRNA",
"Long non-coding RNA",
"Functional RNA",
"piwi-interacting RNA",
"piRNA",
"Long ncRNA",
"microRNA",
"miRNA",
"Small nucleolar RNA",
"Small and long non-coding RNAs",
"Non-coding RNA",
"Small non-coding RNA",
"Regulatory RNA"
],
"description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
},
{
"id": 118,
"uri": "http://edamontology.org/topic_0099",
"label": "RNA",
"synonyms": [
"Small RNA"
],
"description": "RNA sequences and structures."
},
{
"id": 78,
"uri": "http://edamontology.org/topic_0219",
"label": "Data submission, annotation and curation",
"synonyms": [
"Database curation",
"Data curation",
"Data provenance"
],
"description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
},
{
"id": 80,
"uri": "http://edamontology.org/topic_0621",
"label": "Model organisms",
"synonyms": [
"Organisms"
],
"description": "A specific organism, or group of organisms, used to study a particular aspect of biology."
},
{
"id": 25,
"uri": "http://edamontology.org/topic_3125",
"label": "DNA binding sites",
"synonyms": [
"Matrix-attachment region",
"Ribosome binding sites",
"Scaffold-attachment region",
"Matrix/scaffold attachment region",
"Nucleosome exclusion sequences",
"Restriction sites"
],
"description": "Nucleic acids binding to some other molecule."
},
{
"id": 30,
"uri": "http://edamontology.org/topic_2275",
"label": "Molecular modelling",
"synonyms": [
"Comparative modelling",
"Homology modeling",
"Docking",
"Homology modelling",
"Molecular docking"
],
"description": "The construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour, including the modelling the structure of proteins in complex with small molecules or other macromolecules (docking)."
},
{
"id": 66,
"uri": "http://edamontology.org/topic_3511",
"label": "Nucleic acid sites, features and motifs",
"synonyms": [
"Nucleic acid functional sites",
"Primer binding sites",
"Nucleic acid sequence features",
"Sequence tagged sites"
],
"description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in nucleic acid sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 56,
"uri": "http://edamontology.org/topic_0084",
"label": "Phylogeny",
"synonyms": [
"Phylogenetic simulation",
"Phylogenetic clocks",
"Phylogeny reconstruction",
"Phylogenetic stratigraphy",
"Phylogenetic dating"
],
"description": "The study of evolutionary relationships amongst organisms."
},
{
"id": 92,
"uri": "http://edamontology.org/topic_3320",
"label": "RNA splicing",
"synonyms": [
"Alternative splicing",
"Splice sites"
],
"description": "RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons."
},
{
"id": 35,
"uri": "http://edamontology.org/topic_0160",
"label": "Sequence sites, features and motifs",
"synonyms": [
"Sequence profiles",
"Sequence sites",
"Sequence motifs",
"HMMs",
"Functional sites",
"Sequence features"
],
"description": "The archival, detection, prediction and analysis of positional features such as functional and other key sites, in molecular sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 65,
"uri": "http://edamontology.org/topic_0749",
"label": "Transcription factors and regulatory sites",
"synonyms": [
"Attenuators",
"Transcription factors",
"GC signals",
"Terminators",
"-10 signals",
"TFBS",
"Isochores",
"-35 signals",
"Promoters",
"Enhancers",
"Transcriptional regulatory sites",
"TATA signals",
"CCAAT box",
"Transcription factor binding sites",
"CAAT signals",
"CAT box",
"CpG islands"
],
"description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
},
{
"id": 27,
"uri": "http://edamontology.org/topic_0203",
"label": "Gene expression",
"synonyms": [
"DNA chips",
"DNA microarrays",
"Gene translation",
"Transcription",
"Expression",
"Gene expression profiling",
"Codon usage",
"Gene transcription"
],
"description": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data."
}
]
}