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            "id": 100,
            "uri": "http://edamontology.org/topic_3068",
            "label": "Literature and language",
            "synonyms": [
                "Scientific literature",
                "Literature",
                "Language",
                "References",
                "Documentation",
                "Citations",
                "Bibliography"
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            "id": 71,
            "uri": "http://edamontology.org/topic_3299",
            "label": "Evolutionary biology",
            "synonyms": [
                "Evolution"
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            "description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
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            "id": 47,
            "uri": "http://edamontology.org/topic_3382",
            "label": "Imaging",
            "synonyms": [
                "Optical super resolution microscopy",
                "Microscopy",
                "Photonic force microscopy",
                "Photonic microscopy",
                "Diffraction experiment",
                "Microscopy imaging"
            ],
            "description": "The visual representation of an object."
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            "id": 44,
            "uri": "http://edamontology.org/topic_3941",
            "label": "Metatranscriptomics",
            "synonyms": null,
            "description": "The study of microbe gene expression within natural environments (i.e. the metatranscriptome)."
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        {
            "id": 58,
            "uri": "http://edamontology.org/topic_2229",
            "label": "Cell biology",
            "synonyms": [
                "Protein subcellular localization",
                "Cellular processes",
                "Cells"
            ],
            "description": "Cells, such as key genes and proteins involved in the cell cycle."
        },
        {
            "id": 55,
            "uri": "http://edamontology.org/topic_0089",
            "label": "Ontology and terminology",
            "synonyms": [
                "Upper ontology",
                "Terminology",
                "Ontology",
                "Ontologies",
                "Ontology relations",
                "Applied ontology"
            ],
            "description": "The conceptualisation, categorisation and nomenclature (naming) of entities or phenomena within biology or bioinformatics. This includes formal ontologies, controlled vocabularies, structured glossary, symbols and terminology or other related resource."
        },
        {
            "id": 111,
            "uri": "http://edamontology.org/topic_0121",
            "label": "Proteomics",
            "synonyms": [
                "Peptide identification",
                "Quantitative proteomics",
                "MS-based targeted proteomics",
                "Targeted proteomics",
                "Metaproteomics",
                "MS-based untargeted proteomics",
                "Discovery proteomics",
                "Top-down proteomics",
                "Protein and peptide identification",
                "Bottom-up proteomics"
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            "description": "Protein and peptide identification, especially in the study of whole proteomes of organisms."
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        {
            "id": 19,
            "uri": "http://edamontology.org/topic_3534",
            "label": "Protein binding sites",
            "synonyms": [
                "Protein key folding sites",
                "Protein cleavage sites",
                "Enzyme active site",
                "Protein-nucleic acid binding sites",
                "Protein functional sites"
            ],
            "description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
        },
        {
            "id": 97,
            "uri": "http://edamontology.org/topic_0632",
            "label": "Probes and primers",
            "synonyms": [
                "Primers",
                "Primer quality",
                "Probes"
            ],
            "description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
        },
        {
            "id": 98,
            "uri": "http://edamontology.org/topic_3518",
            "label": "Microarray experiment",
            "synonyms": [
                "miRNA array",
                "Proprietary platform micoarray",
                "MicroRNA array",
                "Gene expression microarray",
                "Multichannel microarray",
                "RNA microarrays",
                "Microarrays",
                "mRNA microarray",
                "Reverse phase protein array",
                "One channel microarray",
                "aCGH microarray",
                "Tissue microarray",
                "SNP array",
                "Methylation array",
                "Tiling arrays",
                "RNA chips",
                "Genotyping array",
                "Two channel microarray"
            ],
            "description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
        },
        {
            "id": 83,
            "uri": "http://edamontology.org/topic_3301",
            "label": "Microbiology",
            "synonyms": [
                "Microbial physiology",
                "Microbial genetics",
                "Microbiological surveillance",
                "Molecular microbiology",
                "Medical microbiology",
                "Antimicrobial stewardship",
                "Microbial surveillance",
                "Molecular infection biology"
            ],
            "description": "The biology of microorganisms."
        },
        {
            "id": 41,
            "uri": "http://edamontology.org/topic_0157",
            "label": "Sequence composition, complexity and repeats",
            "synonyms": [
                "Protein sequence repeats",
                "Sequence complexity",
                "Low complexity sequences",
                "Nucleic acid repeats",
                "Repeat sequences",
                "Sequence composition",
                "Sequence repeats",
                "Protein repeats"
            ],
            "description": "The archival, processing and analysis of the basic character composition of molecular sequences, for example character or word frequency, ambiguity, complexity, particularly regions of low complexity, and repeats or the repetitive nature of molecular sequences."
        },
        {
            "id": 39,
            "uri": "http://edamontology.org/topic_0097",
            "label": "Nucleic acid structure analysis",
            "synonyms": [
                "DNA structure",
                "Nucleic acid structure",
                "Nucleic acid denaturation",
                "DNA melting",
                "RNA structure alignment",
                "RNA structure",
                "Nucleic acid thermodynamics",
                "RNA alignment"
            ],
            "description": "The archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation."
        },
        {
            "id": 20,
            "uri": "http://edamontology.org/topic_0154",
            "label": "Small molecules",
            "synonyms": [
                "Peptides and amino acids",
                "Toxins and targets",
                "Drugs and target structures",
                "Drug targets",
                "Peptides",
                "Drug structures",
                "Metabolite structures",
                "Amino acids",
                "Toxins",
                "Targets",
                "Chemical structures",
                "Target structures"
            ],
            "description": "Small molecules of biological significance, typically archival, curation, processing and analysis of structural information."
        },
        {
            "id": 112,
            "uri": "http://edamontology.org/topic_3420",
            "label": "Reproductive health",
            "synonyms": [
                "Andrology",
                "Family planning",
                "Reproductive_health",
                "Reproductive disorders",
                "Fertility medicine"
            ],
            "description": "The health of the reproductive processes, functions and systems at all stages of life."
        },
        {
            "id": 43,
            "uri": "http://edamontology.org/topic_3321",
            "label": "Molecular genetics",
            "synonyms": null,
            "description": "The structure and function of genes at a molecular level."
        },
        {
            "id": 42,
            "uri": "http://edamontology.org/topic_3366",
            "label": "Data integration and warehousing",
            "synonyms": [
                "Data integration",
                "Data warehousing"
            ],
            "description": "The combination and integration of data from different sources, for example into a central repository or warehouse, to provide users with a unified view of these data."
        },
        {
            "id": 103,
            "uri": "http://edamontology.org/topic_0659",
            "label": "Functional, regulatory and non-coding RNA",
            "synonyms": [
                "lncRNA",
                "Small ncRNA",
                "Small interfering RNA",
                "Small nuclear RNA",
                "siRNA",
                "ncRNA",
                "snRNA",
                "snoRNA",
                "Long non-coding RNA",
                "Functional RNA",
                "piwi-interacting RNA",
                "piRNA",
                "Long ncRNA",
                "microRNA",
                "miRNA",
                "Small nucleolar RNA",
                "Small and long non-coding RNAs",
                "Non-coding RNA",
                "Small non-coding RNA",
                "Regulatory RNA"
            ],
            "description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
        },
        {
            "id": 118,
            "uri": "http://edamontology.org/topic_0099",
            "label": "RNA",
            "synonyms": [
                "Small RNA"
            ],
            "description": "RNA sequences and structures."
        },
        {
            "id": 78,
            "uri": "http://edamontology.org/topic_0219",
            "label": "Data submission, annotation and curation",
            "synonyms": [
                "Database curation",
                "Data curation",
                "Data provenance"
            ],
            "description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
        }
    ]
}