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{
    "count": 140,
    "next": "https://catalogue.france-bioinformatique.fr/api/topic/?format=api&limit=20&offset=80",
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    "results": [
        {
            "id": 76,
            "uri": "http://edamontology.org/topic_3332",
            "label": "Computational chemistry",
            "synonyms": null,
            "description": "Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of chemical systems."
        },
        {
            "id": 44,
            "uri": "http://edamontology.org/topic_3941",
            "label": "Metatranscriptomics",
            "synonyms": null,
            "description": "The study of microbe gene expression within natural environments (i.e. the metatranscriptome)."
        },
        {
            "id": 46,
            "uri": "http://edamontology.org/topic_3387",
            "label": "Marine biology",
            "synonyms": null,
            "description": "The study of organisms in the ocean or brackish waters."
        },
        {
            "id": 111,
            "uri": "http://edamontology.org/topic_0121",
            "label": "Proteomics",
            "synonyms": [
                "Peptide identification",
                "Quantitative proteomics",
                "MS-based targeted proteomics",
                "Targeted proteomics",
                "Metaproteomics",
                "MS-based untargeted proteomics",
                "Discovery proteomics",
                "Top-down proteomics",
                "Protein and peptide identification",
                "Bottom-up proteomics"
            ],
            "description": "Protein and peptide identification, especially in the study of whole proteomes of organisms."
        },
        {
            "id": 97,
            "uri": "http://edamontology.org/topic_0632",
            "label": "Probes and primers",
            "synonyms": [
                "Primers",
                "Primer quality",
                "Probes"
            ],
            "description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
        },
        {
            "id": 112,
            "uri": "http://edamontology.org/topic_3420",
            "label": "Reproductive health",
            "synonyms": [
                "Andrology",
                "Family planning",
                "Reproductive_health",
                "Reproductive disorders",
                "Fertility medicine"
            ],
            "description": "The health of the reproductive processes, functions and systems at all stages of life."
        },
        {
            "id": 43,
            "uri": "http://edamontology.org/topic_3321",
            "label": "Molecular genetics",
            "synonyms": null,
            "description": "The structure and function of genes at a molecular level."
        },
        {
            "id": 5,
            "uri": "http://edamontology.org/topic_3572",
            "label": "Data quality management",
            "synonyms": [
                "Data integrity",
                "Data cleaning",
                "Data quality",
                "Data clean-up"
            ],
            "description": "The quality, integrity, and cleaning up of data."
        },
        {
            "id": 20,
            "uri": "http://edamontology.org/topic_0154",
            "label": "Small molecules",
            "synonyms": [
                "Peptides and amino acids",
                "Toxins and targets",
                "Drugs and target structures",
                "Drug targets",
                "Peptides",
                "Drug structures",
                "Metabolite structures",
                "Amino acids",
                "Toxins",
                "Targets",
                "Chemical structures",
                "Target structures"
            ],
            "description": "Small molecules of biological significance, typically archival, curation, processing and analysis of structural information."
        },
        {
            "id": 100,
            "uri": "http://edamontology.org/topic_3068",
            "label": "Literature and language",
            "synonyms": [
                "Scientific literature",
                "Literature",
                "Language",
                "References",
                "Documentation",
                "Citations",
                "Bibliography"
            ],
            "description": "The scientific literature, language processing, reference information, and documentation."
        },
        {
            "id": 71,
            "uri": "http://edamontology.org/topic_3299",
            "label": "Evolutionary biology",
            "synonyms": [
                "Evolution"
            ],
            "description": "The evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity."
        },
        {
            "id": 114,
            "uri": "http://edamontology.org/topic_1775",
            "label": "Function analysis",
            "synonyms": [
                "Protein function analysis",
                "Protein function prediction",
                "Functional analysis"
            ],
            "description": "The study of gene and protein function including the prediction of functional properties of a protein."
        },
        {
            "id": 30,
            "uri": "http://edamontology.org/topic_2275",
            "label": "Molecular modelling",
            "synonyms": [
                "Comparative modelling",
                "Homology modeling",
                "Docking",
                "Homology modelling",
                "Molecular docking"
            ],
            "description": "The construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour, including the modelling the structure of proteins in complex with small molecules or other macromolecules (docking)."
        },
        {
            "id": 56,
            "uri": "http://edamontology.org/topic_0084",
            "label": "Phylogeny",
            "synonyms": [
                "Phylogenetic simulation",
                "Phylogenetic clocks",
                "Phylogeny reconstruction",
                "Phylogenetic stratigraphy",
                "Phylogenetic dating"
            ],
            "description": "The study of evolutionary relationships amongst organisms."
        },
        {
            "id": 50,
            "uri": "http://edamontology.org/topic_3510",
            "label": "Protein sites, features and motifs",
            "synonyms": [
                "Protein sequence features",
                "Signal peptide cleavage sites"
            ],
            "description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in protein sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
        },
        {
            "id": 78,
            "uri": "http://edamontology.org/topic_0219",
            "label": "Data submission, annotation and curation",
            "synonyms": [
                "Database curation",
                "Data curation",
                "Data provenance"
            ],
            "description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
        },
        {
            "id": 27,
            "uri": "http://edamontology.org/topic_0203",
            "label": "Gene expression",
            "synonyms": [
                "DNA chips",
                "DNA microarrays",
                "Gene translation",
                "Transcription",
                "Expression",
                "Gene expression profiling",
                "Codon usage",
                "Gene transcription"
            ],
            "description": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data."
        },
        {
            "id": 13,
            "uri": "http://edamontology.org/topic_3170",
            "label": "RNA-Seq",
            "synonyms": [
                "RNA sequencing",
                "RNA-Seq analysis",
                "Whole transcriptome shotgun sequencing",
                "WTSS",
                "Small-Seq",
                "Small RNA sequencing",
                "Small RNA-Seq",
                "miRNA-seq",
                "MicroRNA sequencing",
                "Transcriptome profiling"
            ],
            "description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
        },
        {
            "id": 66,
            "uri": "http://edamontology.org/topic_3511",
            "label": "Nucleic acid sites, features and motifs",
            "synonyms": [
                "Nucleic acid functional sites",
                "Primer binding sites",
                "Nucleic acid sequence features",
                "Sequence tagged sites"
            ],
            "description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in nucleic acid sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
        },
        {
            "id": 25,
            "uri": "http://edamontology.org/topic_3125",
            "label": "DNA binding sites",
            "synonyms": [
                "Matrix-attachment region",
                "Ribosome binding sites",
                "Scaffold-attachment region",
                "Matrix/scaffold attachment region",
                "Nucleosome exclusion sequences",
                "Restriction sites"
            ],
            "description": "Nucleic acids binding to some other molecule."
        }
    ]
}