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{
    "count": 127,
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        {
            "id": 99,
            "uri": "http://edamontology.org/topic_0736",
            "label": "Protein folds and structural domains",
            "synonyms": [
                "Protein domains",
                "Protein membrane regions",
                "Protein folds",
                "Protein transmembrane regions",
                "Protein topological domains",
                "Protein structural domains",
                "Intramembrane regions",
                "Transmembrane regions"
            ],
            "description": "Protein tertiary structural domains and folds in a protein or polypeptide chain."
        },
        {
            "id": 65,
            "uri": "http://edamontology.org/topic_0749",
            "label": "Transcription factors and regulatory sites",
            "synonyms": [
                "Attenuators",
                "Transcription factors",
                "GC signals",
                "Terminators",
                "-10 signals",
                "TFBS",
                "Isochores",
                "-35 signals",
                "Promoters",
                "Enhancers",
                "Transcriptional regulatory sites",
                "TATA signals",
                "CCAAT box",
                "Transcription factor binding sites",
                "CAAT signals",
                "CAT box",
                "CpG islands"
            ],
            "description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
        },
        {
            "id": 49,
            "uri": "http://edamontology.org/topic_0769",
            "label": "Workflows",
            "synonyms": [
                "Software integration",
                "Pipelines",
                "Tool interoperability",
                "Tool integration"
            ],
            "description": "Biological or biomedical analytical workflows or pipelines."
        },
        {
            "id": 86,
            "uri": "http://edamontology.org/topic_0780",
            "label": "Plant biology",
            "synonyms": [
                "Plant",
                "Plant physiology",
                "Plant anatomy",
                "Plant ecology",
                "Plant genetics",
                "Botany",
                "Plant science",
                "Plants",
                "Plant cell biology"
            ],
            "description": "Plants, e.g. information on a specific plant genome including molecular sequences, genes and annotation."
        },
        {
            "id": 90,
            "uri": "http://edamontology.org/topic_0781",
            "label": "Virology",
            "synonyms": null,
            "description": "Study of viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation."
        },
        {
            "id": 81,
            "uri": "http://edamontology.org/topic_0797",
            "label": "Comparative genomics",
            "synonyms": null,
            "description": "The study (typically comparison) of the sequence, structure or function of multiple genomes."
        },
        {
            "id": 3,
            "uri": "http://edamontology.org/topic_0798",
            "label": "Mobile genetic elements",
            "synonyms": [
                "Transposons"
            ],
            "description": "Mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns."
        },
        {
            "id": 110,
            "uri": "http://edamontology.org/topic_0804",
            "label": "Immunology",
            "synonyms": null,
            "description": "The application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on."
        },
        {
            "id": 33,
            "uri": "http://edamontology.org/topic_1317",
            "label": "Structural biology",
            "synonyms": [
                "Structural determination",
                "Structural assignment",
                "Structure determination"
            ],
            "description": "The molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids."
        },
        {
            "id": 114,
            "uri": "http://edamontology.org/topic_1775",
            "label": "Function analysis",
            "synonyms": [
                "Protein function analysis",
                "Protein function prediction",
                "Functional analysis"
            ],
            "description": "The study of gene and protein function including the prediction of functional properties of a protein."
        },
        {
            "id": 58,
            "uri": "http://edamontology.org/topic_2229",
            "label": "Cell biology",
            "synonyms": [
                "Protein subcellular localization",
                "Cellular processes",
                "Cells"
            ],
            "description": "Cells, such as key genes and proteins involved in the cell cycle."
        },
        {
            "id": 79,
            "uri": "http://edamontology.org/topic_2259",
            "label": "Systems biology",
            "synonyms": [
                "Biological system modelling",
                "Systems modelling",
                "Biological modelling"
            ],
            "description": "The holistic modelling and analysis of complex biological systems and the interactions therein."
        },
        {
            "id": 14,
            "uri": "http://edamontology.org/topic_2269",
            "label": "Statistics and probability",
            "synonyms": [
                "Biostatistics",
                "Multivariate statistics",
                "Bayesian methods",
                "Gaussian processes",
                "Probability",
                "Markov processes",
                "Probabilistic graphical model",
                "Inferential statistics",
                "Descriptive statistics",
                "Statistics"
            ],
            "description": "The application of statistical methods to biological problems."
        },
        {
            "id": 30,
            "uri": "http://edamontology.org/topic_2275",
            "label": "Molecular modelling",
            "synonyms": [
                "Comparative modelling",
                "Homology modeling",
                "Docking",
                "Homology modelling",
                "Molecular docking"
            ],
            "description": "The construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour, including the modelling the structure of proteins in complex with small molecules or other macromolecules (docking)."
        },
        {
            "id": 113,
            "uri": "http://edamontology.org/topic_2814",
            "label": "Protein structure analysis",
            "synonyms": [
                "Protein tertiary structure",
                "Protein structure"
            ],
            "description": "Protein secondary or tertiary structural data and/or associated annotation."
        },
        {
            "id": 11,
            "uri": "http://edamontology.org/topic_2815",
            "label": "Human biology",
            "synonyms": [
                "Humans"
            ],
            "description": "The study of human beings in general, including the human genome and proteome."
        },
        {
            "id": 21,
            "uri": "http://edamontology.org/topic_2828",
            "label": "X-ray diffraction",
            "synonyms": [
                "X-ray crystallography",
                "X-ray microscopy",
                "Crystallography"
            ],
            "description": "The study of matter and their structure by means of the diffraction of X-rays, typically the diffraction pattern caused by the regularly spaced atoms of a crystalline sample."
        },
        {
            "id": 120,
            "uri": "http://edamontology.org/topic_2840",
            "label": "Toxicology",
            "synonyms": [
                "Toxicoinformatics",
                "Computational toxicology"
            ],
            "description": "Toxins and the adverse effects of these chemical substances on living organisms."
        },
        {
            "id": 4,
            "uri": "http://edamontology.org/topic_2885",
            "label": "DNA polymorphism",
            "synonyms": [
                "Microsatellites",
                "SNP",
                "Variable number of tandem repeat polymorphism",
                "snps",
                "Single nucleotide polymorphism",
                "VNTR",
                "RFLP"
            ],
            "description": "DNA polymorphism."
        },
        {
            "id": 67,
            "uri": "http://edamontology.org/topic_3050",
            "label": "Biodiversity",
            "synonyms": null,
            "description": "The degree of variation of life forms within a given ecosystem, biome or an entire planet."
        }
    ]
}