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"id": 69,
"uri": "http://edamontology.org/topic_3943",
"label": "Paleogenomics",
"synonyms": [
"Paleogenetics",
"Ancestral genomes"
],
"description": "The reconstruction and analysis of genomic information in extinct species."
},
{
"id": 115,
"uri": "http://edamontology.org/topic_0166",
"label": "Protein structural motifs and surfaces",
"synonyms": [
"Protein surfaces",
"Protein structural features",
"Protein 3D motifs",
"Structural motifs",
"Protein structural motifs"
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"description": "Structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules."
},
{
"id": 3,
"uri": "http://edamontology.org/topic_0798",
"label": "Mobile genetic elements",
"synonyms": [
"Transposons"
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"description": "Mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns."
},
{
"id": 15,
"uri": "http://edamontology.org/topic_3517",
"label": "GWAS study",
"synonyms": [
"GWAS",
"Genome-wide association study",
"GWAS analysis"
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"description": "Genome-wide association study experiments."
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{
"id": 67,
"uri": "http://edamontology.org/topic_3050",
"label": "Biodiversity",
"synonyms": null,
"description": "The degree of variation of life forms within a given ecosystem, biome or an entire planet."
},
{
"id": 1,
"uri": "http://edamontology.org/topic_3697",
"label": "Microbial ecology",
"synonyms": [
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"Community analysis",
"Microbiome",
"Environmental microbiology"
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"description": "The ecology of microorganisms including their relationship with one another and their environment."
},
{
"id": 6,
"uri": "http://edamontology.org/topic_3365",
"label": "Data architecture, analysis and design",
"synonyms": [
"Data analysis",
"Data design",
"Data architecture"
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"description": "The development of policies, models and standards that cover data acquisition, storage and integration, such that it can be put to use, typically through a process of systematically applying statistical and / or logical techniques to describe, illustrate, summarise or evaluate data."
},
{
"id": 82,
"uri": "http://edamontology.org/topic_0085",
"label": "Functional genomics",
"synonyms": null,
"description": "The study of gene or protein functions and their interactions in totality in a given organism, tissue, cell etc."
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{
"id": 122,
"uri": "http://edamontology.org/topic_3360",
"label": "Biomarkers",
"synonyms": [
"Diagnostic markers"
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"description": "Objective indicators of biological state often used to assess health, and determinate treatment."
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{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
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"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 106,
"uri": "http://edamontology.org/topic_3520",
"label": "Proteomics experiment",
"synonyms": [
"2D PAGE experiment",
"Spectrum demultiplexing",
"Mass spectrometry experiments",
"MS",
"Northern blot experiment",
"MS experiments",
"DIA",
"Mass spectrometry",
"Data-independent acquisition"
],
"description": "Proteomics experiments."
},
{
"id": 37,
"uri": "http://edamontology.org/topic_3948",
"label": "Immunoinformatics",
"synonyms": [
"Computational immunology"
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"description": "Immunoinformatics is the field of computational biology that deals with the study of immunoloogical questions. Immunoinformatics is at the interface between immunology and computer science. It takes advantage of computational, statistical, mathematical approaches and enhances the understanding of immunological knowledge."
},
{
"id": 19,
"uri": "http://edamontology.org/topic_3534",
"label": "Protein binding sites",
"synonyms": [
"Protein key folding sites",
"Protein cleavage sites",
"Enzyme active site",
"Protein-nucleic acid binding sites",
"Protein functional sites"
],
"description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
},
{
"id": 43,
"uri": "http://edamontology.org/topic_3321",
"label": "Molecular genetics",
"synonyms": null,
"description": "The structure and function of genes at a molecular level."
},
{
"id": 76,
"uri": "http://edamontology.org/topic_3332",
"label": "Computational chemistry",
"synonyms": null,
"description": "Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of chemical systems."
},
{
"id": 100,
"uri": "http://edamontology.org/topic_3068",
"label": "Literature and language",
"synonyms": [
"Scientific literature",
"Literature",
"Language",
"References",
"Documentation",
"Citations",
"Bibliography"
],
"description": "The scientific literature, language processing, reference information, and documentation."
},
{
"id": 47,
"uri": "http://edamontology.org/topic_3382",
"label": "Imaging",
"synonyms": [
"Optical super resolution microscopy",
"Microscopy",
"Photonic force microscopy",
"Photonic microscopy",
"Diffraction experiment",
"Microscopy imaging"
],
"description": "The visual representation of an object."
},
{
"id": 39,
"uri": "http://edamontology.org/topic_0097",
"label": "Nucleic acid structure analysis",
"synonyms": [
"DNA structure",
"Nucleic acid structure",
"Nucleic acid denaturation",
"DNA melting",
"RNA structure alignment",
"RNA structure",
"Nucleic acid thermodynamics",
"RNA alignment"
],
"description": "The archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation."
},
{
"id": 111,
"uri": "http://edamontology.org/topic_0121",
"label": "Proteomics",
"synonyms": [
"Peptide identification",
"Quantitative proteomics",
"MS-based targeted proteomics",
"Targeted proteomics",
"Metaproteomics",
"MS-based untargeted proteomics",
"Discovery proteomics",
"Top-down proteomics",
"Protein and peptide identification",
"Bottom-up proteomics"
],
"description": "Protein and peptide identification, especially in the study of whole proteomes of organisms."
},
{
"id": 97,
"uri": "http://edamontology.org/topic_0632",
"label": "Probes and primers",
"synonyms": [
"Primers",
"Primer quality",
"Probes"
],
"description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
}
]
}