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"uri": "http://edamontology.org/topic_3372",
"label": "Software engineering",
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"Algorithms",
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"Data structures",
"Programming languages"
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"id": 106,
"uri": "http://edamontology.org/topic_3520",
"label": "Proteomics experiment",
"synonyms": [
"2D PAGE experiment",
"Spectrum demultiplexing",
"Mass spectrometry experiments",
"MS",
"Northern blot experiment",
"MS experiments",
"DIA",
"Mass spectrometry",
"Data-independent acquisition"
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{
"id": 105,
"uri": "http://edamontology.org/topic_3169",
"label": "ChIP-seq",
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"ChIP-sequencing",
"Chip sequencing",
"Chip Seq",
"ChIP-exo",
"Chip-sequencing"
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"description": "The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."
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{
"id": 104,
"uri": "http://edamontology.org/topic_0082",
"label": "Structure prediction",
"synonyms": [
"Nucleic acid design",
"Nucleic acid folding",
"RNA structure prediction",
"Protein structure prediction",
"Nucleic acid structure prediction",
"DNA structure prediction",
"Protein fold recognition"
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"description": "The prediction of molecular structure, including the prediction, modelling, recognition or design of protein secondary or tertiary structure or other structural features, and the folding of nucleic acid molecules and the prediction or design of nucleic acid (typically RNA) sequences with specific conformations."
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{
"id": 103,
"uri": "http://edamontology.org/topic_0659",
"label": "Functional, regulatory and non-coding RNA",
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"Small ncRNA",
"Small interfering RNA",
"Small nuclear RNA",
"siRNA",
"ncRNA",
"snRNA",
"snoRNA",
"Long non-coding RNA",
"Functional RNA",
"piwi-interacting RNA",
"piRNA",
"Long ncRNA",
"microRNA",
"miRNA",
"Small nucleolar RNA",
"Small and long non-coding RNAs",
"Non-coding RNA",
"Small non-coding RNA",
"Regulatory RNA"
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"description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
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"id": 102,
"uri": "http://edamontology.org/topic_3056",
"label": "Population genetics",
"synonyms": null,
"description": "The distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow."
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{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
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"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
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"id": 100,
"uri": "http://edamontology.org/topic_3068",
"label": "Literature and language",
"synonyms": [
"Scientific literature",
"Literature",
"Language",
"References",
"Documentation",
"Citations",
"Bibliography"
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"description": "The scientific literature, language processing, reference information, and documentation."
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{
"id": 99,
"uri": "http://edamontology.org/topic_0736",
"label": "Protein folds and structural domains",
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"Protein domains",
"Protein membrane regions",
"Protein folds",
"Protein transmembrane regions",
"Protein topological domains",
"Protein structural domains",
"Intramembrane regions",
"Transmembrane regions"
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"description": "Protein tertiary structural domains and folds in a protein or polypeptide chain."
},
{
"id": 98,
"uri": "http://edamontology.org/topic_3518",
"label": "Microarray experiment",
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"miRNA array",
"Proprietary platform micoarray",
"MicroRNA array",
"Gene expression microarray",
"Multichannel microarray",
"RNA microarrays",
"Microarrays",
"mRNA microarray",
"Reverse phase protein array",
"One channel microarray",
"aCGH microarray",
"Tissue microarray",
"SNP array",
"Methylation array",
"Tiling arrays",
"RNA chips",
"Genotyping array",
"Two channel microarray"
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"description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
},
{
"id": 97,
"uri": "http://edamontology.org/topic_0632",
"label": "Probes and primers",
"synonyms": [
"Primers",
"Primer quality",
"Probes"
],
"description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
},
{
"id": 96,
"uri": "http://edamontology.org/topic_0634",
"label": "Pathology",
"synonyms": [
"Pathology",
"Disease"
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"description": "Diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases."
},
{
"id": 95,
"uri": "http://edamontology.org/topic_3574",
"label": "Human genetics",
"synonyms": null,
"description": "The study of inheritance in human beings."
},
{
"id": 94,
"uri": "http://edamontology.org/topic_3571",
"label": "Data governance",
"synonyms": [
"Data stewardship"
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"description": "The control of data entry and maintenance to ensure the data meets defined standards, qualities or constraints."
},
{
"id": 93,
"uri": "http://edamontology.org/topic_0199",
"label": "Genetic variation",
"synonyms": [
"DNA variation",
"Somatic mutations",
"Genomic variation",
"Mutation",
"Polymorphism"
],
"description": "Stable, naturally occuring mutations in a nucleotide sequence including alleles, naturally occurring mutations such as single base nucleotide substitutions, deletions and insertions, RFLPs and other polymorphisms."
},
{
"id": 92,
"uri": "http://edamontology.org/topic_3320",
"label": "RNA splicing",
"synonyms": [
"Alternative splicing",
"Splice sites"
],
"description": "RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons."
},
{
"id": 91,
"uri": "http://edamontology.org/topic_3324",
"label": "Infectious disease",
"synonyms": [
"Transmissable disease",
"Communicable disease"
],
"description": "The branch of medicine that deals with the prevention, diagnosis and management of transmissable disease with clinically evident illness resulting from infection with pathogenic biological agents (viruses, bacteria, fungi, protozoa, parasites and prions)."
},
{
"id": 90,
"uri": "http://edamontology.org/topic_0781",
"label": "Virology",
"synonyms": null,
"description": "Study of viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation."
},
{
"id": 89,
"uri": "http://edamontology.org/topic_3957",
"label": "Protein interaction experiment",
"synonyms": [
"Phage display",
"Yeast one-hybrid",
"Co-immunoprecipitation",
"Yeast two-hybrid"
],
"description": "An experiment for studying protein-protein interactions."
},
{
"id": 88,
"uri": "http://edamontology.org/topic_0091",
"label": "Bioinformatics",
"synonyms": null,
"description": "The archival, curation, processing and analysis of complex biological data."
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