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"id": 116,
"uri": "http://edamontology.org/topic_3542",
"label": "Protein secondary structure",
"synonyms": [
"Protein super-secondary structure",
"Protein features (secondary structure)"
],
"description": "Secondary structure (predicted or real) of a protein, including super-secondary structure."
},
{
"id": 115,
"uri": "http://edamontology.org/topic_0166",
"label": "Protein structural motifs and surfaces",
"synonyms": [
"Protein surfaces",
"Protein structural features",
"Protein 3D motifs",
"Structural motifs",
"Protein structural motifs"
],
"description": "Structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules."
},
{
"id": 114,
"uri": "http://edamontology.org/topic_1775",
"label": "Function analysis",
"synonyms": [
"Protein function analysis",
"Protein function prediction",
"Functional analysis"
],
"description": "The study of gene and protein function including the prediction of functional properties of a protein."
},
{
"id": 113,
"uri": "http://edamontology.org/topic_2814",
"label": "Protein structure analysis",
"synonyms": [
"Protein tertiary structure",
"Protein structure"
],
"description": "Protein secondary or tertiary structural data and/or associated annotation."
},
{
"id": 112,
"uri": "http://edamontology.org/topic_3420",
"label": "Reproductive health",
"synonyms": [
"Andrology",
"Family planning",
"Reproductive_health",
"Reproductive disorders",
"Fertility medicine"
],
"description": "The health of the reproductive processes, functions and systems at all stages of life."
},
{
"id": 111,
"uri": "http://edamontology.org/topic_0121",
"label": "Proteomics",
"synonyms": [
"Peptide identification",
"Quantitative proteomics",
"MS-based targeted proteomics",
"Targeted proteomics",
"Metaproteomics",
"MS-based untargeted proteomics",
"Discovery proteomics",
"Top-down proteomics",
"Protein and peptide identification",
"Bottom-up proteomics"
],
"description": "Protein and peptide identification, especially in the study of whole proteomes of organisms."
},
{
"id": 110,
"uri": "http://edamontology.org/topic_0804",
"label": "Immunology",
"synonyms": null,
"description": "The application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on."
},
{
"id": 109,
"uri": "http://edamontology.org/topic_3678",
"label": "Experimental design and studies",
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"Experimental design",
"Design of experiments"
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"description": "The design of an experiment intended to test a hypothesis, and describe or explain empirical data obtained under various experimental conditions."
},
{
"id": 108,
"uri": "http://edamontology.org/topic_3523",
"label": "RNAi experiment",
"synonyms": null,
"description": "RNAi experiments."
},
{
"id": 107,
"uri": "http://edamontology.org/topic_3372",
"label": "Software engineering",
"synonyms": [
"Computer programming",
"Algorithms",
"Software development",
"Data structures",
"Programming languages"
],
"description": "The process that leads from an original formulation of a computing problem to executable programs."
},
{
"id": 106,
"uri": "http://edamontology.org/topic_3520",
"label": "Proteomics experiment",
"synonyms": [
"2D PAGE experiment",
"Spectrum demultiplexing",
"Mass spectrometry experiments",
"MS",
"Northern blot experiment",
"MS experiments",
"DIA",
"Mass spectrometry",
"Data-independent acquisition"
],
"description": "Proteomics experiments."
},
{
"id": 105,
"uri": "http://edamontology.org/topic_3169",
"label": "ChIP-seq",
"synonyms": [
"ChIP-sequencing",
"Chip sequencing",
"Chip Seq",
"ChIP-exo",
"Chip-sequencing"
],
"description": "The analysis of protein-DNA interactions where chromatin immunoprecipitation (ChIP) is used in combination with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins."
},
{
"id": 104,
"uri": "http://edamontology.org/topic_0082",
"label": "Structure prediction",
"synonyms": [
"Nucleic acid design",
"Nucleic acid folding",
"RNA structure prediction",
"Protein structure prediction",
"Nucleic acid structure prediction",
"DNA structure prediction",
"Protein fold recognition"
],
"description": "The prediction of molecular structure, including the prediction, modelling, recognition or design of protein secondary or tertiary structure or other structural features, and the folding of nucleic acid molecules and the prediction or design of nucleic acid (typically RNA) sequences with specific conformations."
},
{
"id": 103,
"uri": "http://edamontology.org/topic_0659",
"label": "Functional, regulatory and non-coding RNA",
"synonyms": [
"lncRNA",
"Small ncRNA",
"Small interfering RNA",
"Small nuclear RNA",
"siRNA",
"ncRNA",
"snRNA",
"snoRNA",
"Long non-coding RNA",
"Functional RNA",
"piwi-interacting RNA",
"piRNA",
"Long ncRNA",
"microRNA",
"miRNA",
"Small nucleolar RNA",
"Small and long non-coding RNAs",
"Non-coding RNA",
"Small non-coding RNA",
"Regulatory RNA"
],
"description": "Non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA)."
},
{
"id": 102,
"uri": "http://edamontology.org/topic_3056",
"label": "Population genetics",
"synonyms": null,
"description": "The distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow."
},
{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
],
"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 100,
"uri": "http://edamontology.org/topic_3068",
"label": "Literature and language",
"synonyms": [
"Scientific literature",
"Literature",
"Language",
"References",
"Documentation",
"Citations",
"Bibliography"
],
"description": "The scientific literature, language processing, reference information, and documentation."
},
{
"id": 99,
"uri": "http://edamontology.org/topic_0736",
"label": "Protein folds and structural domains",
"synonyms": [
"Protein domains",
"Protein membrane regions",
"Protein folds",
"Protein transmembrane regions",
"Protein topological domains",
"Protein structural domains",
"Intramembrane regions",
"Transmembrane regions"
],
"description": "Protein tertiary structural domains and folds in a protein or polypeptide chain."
},
{
"id": 98,
"uri": "http://edamontology.org/topic_3518",
"label": "Microarray experiment",
"synonyms": [
"miRNA array",
"Proprietary platform micoarray",
"MicroRNA array",
"Gene expression microarray",
"Multichannel microarray",
"RNA microarrays",
"Microarrays",
"mRNA microarray",
"Reverse phase protein array",
"One channel microarray",
"aCGH microarray",
"Tissue microarray",
"SNP array",
"Methylation array",
"Tiling arrays",
"RNA chips",
"Genotyping array",
"Two channel microarray"
],
"description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
},
{
"id": 97,
"uri": "http://edamontology.org/topic_0632",
"label": "Probes and primers",
"synonyms": [
"Primers",
"Primer quality",
"Probes"
],
"description": "Molecular probes (e.g. a peptide probe or DNA microarray probe) or PCR primers and hybridisation oligos in a nucleic acid sequence."
}
]
}