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{
"id": 54,
"uri": "http://edamontology.org/topic_3065",
"label": "Embryology",
"synonyms": null,
"description": "The development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage."
},
{
"id": 53,
"uri": "http://edamontology.org/topic_3383",
"label": "Bioimaging",
"synonyms": [
"Biological imaging"
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"description": "The use of imaging techniques to understand biology."
},
{
"id": 52,
"uri": "http://edamontology.org/topic_3679",
"label": "Animal study",
"synonyms": [
"Challenge study"
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"description": "The design of an experiment involving non-human animals."
},
{
"id": 33,
"uri": "http://edamontology.org/topic_1317",
"label": "Structural biology",
"synonyms": [
"Structural determination",
"Structural assignment",
"Structure determination"
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"description": "The molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids."
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{
"id": 32,
"uri": "http://edamontology.org/topic_0593",
"label": "NMR",
"synonyms": [
"Nuclear Overhauser Effect Spectroscopy",
"Rotational Frame Nuclear Overhauser Effect Spectroscopy",
"ROESY",
"Nuclear magnetic resonance spectroscopy",
"NOESY",
"NMR spectroscopy",
"Heteronuclear Overhauser Effect Spectroscopy",
"HOESY"
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"description": "An analytical technique that exploits the magenetic properties of certain atomic nuclei to provide information on the structure, dynamics, reaction state and chemical environment of molecules."
},
{
"id": 31,
"uri": "http://edamontology.org/topic_0176",
"label": "Molecular dynamics",
"synonyms": [
"Protein dynamics"
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"description": "The study and simulation of molecular (typically protein) conformation using a computational model of physical forces and computer simulation."
},
{
"id": 29,
"uri": "http://edamontology.org/topic_3306",
"label": "Biophysics",
"synonyms": [
"Medical physics"
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"description": "The use of physics to study biological system."
},
{
"id": 48,
"uri": "http://edamontology.org/topic_3298",
"label": "Phenomics",
"synonyms": null,
"description": "Phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors."
},
{
"id": 12,
"uri": "http://edamontology.org/topic_0102",
"label": "Mapping",
"synonyms": [
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"Synteny",
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"Linkage mapping"
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"description": "The mapping of complete (typically nucleotide) sequences. Mapping (in the sense of short read alignment, or more generally, just alignment) has application in RNA-Seq analysis (mapping of transcriptomics reads), variant discovery (e.g. mapping of exome capture), and re-sequencing (mapping of WGS reads)."
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{
"id": 57,
"uri": "http://edamontology.org/topic_3064",
"label": "Developmental biology",
"synonyms": [
"Development"
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"description": "How organisms grow and develop."
},
{
"id": 117,
"uri": "http://edamontology.org/topic_0114",
"label": "Gene structure",
"synonyms": [
"Fusion genes",
"Gene features"
],
"description": "Gene structure, regions which make an RNA product and features such as promoters, coding regions, gene fusion, splice sites etc."
},
{
"id": 108,
"uri": "http://edamontology.org/topic_3523",
"label": "RNAi experiment",
"synonyms": null,
"description": "RNAi experiments."
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{
"id": 109,
"uri": "http://edamontology.org/topic_3678",
"label": "Experimental design and studies",
"synonyms": [
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"Experimental design",
"Design of experiments"
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"description": "The design of an experiment intended to test a hypothesis, and describe or explain empirical data obtained under various experimental conditions."
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{
"id": 17,
"uri": "http://edamontology.org/topic_0605",
"label": "Informatics",
"synonyms": [
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"Knowledge management",
"Information management"
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"description": "The study and practice of information processing and use of computer information systems."
},
{
"id": 34,
"uri": "http://edamontology.org/topic_3391",
"label": "Omics",
"synonyms": null,
"description": "The collective characterisation and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms."
},
{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
],
"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 69,
"uri": "http://edamontology.org/topic_3943",
"label": "Paleogenomics",
"synonyms": [
"Paleogenetics",
"Ancestral genomes"
],
"description": "The reconstruction and analysis of genomic information in extinct species."
},
{
"id": 4,
"uri": "http://edamontology.org/topic_2885",
"label": "DNA polymorphism",
"synonyms": [
"Microsatellites",
"SNP",
"Variable number of tandem repeat polymorphism",
"snps",
"Single nucleotide polymorphism",
"VNTR",
"RFLP"
],
"description": "DNA polymorphism."
},
{
"id": 116,
"uri": "http://edamontology.org/topic_3542",
"label": "Protein secondary structure",
"synonyms": [
"Protein super-secondary structure",
"Protein features (secondary structure)"
],
"description": "Secondary structure (predicted or real) of a protein, including super-secondary structure."
},
{
"id": 115,
"uri": "http://edamontology.org/topic_0166",
"label": "Protein structural motifs and surfaces",
"synonyms": [
"Protein surfaces",
"Protein structural features",
"Protein 3D motifs",
"Structural motifs",
"Protein structural motifs"
],
"description": "Structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules."
}
]
}