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"id": 14,
"uri": "http://edamontology.org/topic_2269",
"label": "Statistics and probability",
"synonyms": [
"Biostatistics",
"Multivariate statistics",
"Bayesian methods",
"Gaussian processes",
"Probability",
"Markov processes",
"Probabilistic graphical model",
"Inferential statistics",
"Descriptive statistics",
"Statistics"
],
"description": "The application of statistical methods to biological problems."
},
{
"id": 33,
"uri": "http://edamontology.org/topic_1317",
"label": "Structural biology",
"synonyms": [
"Structural determination",
"Structural assignment",
"Structure determination"
],
"description": "The molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids."
},
{
"id": 128,
"uri": "http://edamontology.org/topic_3175",
"label": "Structural variation",
"synonyms": [
"DNA structural variation",
"Genomic structural variation",
"Deletion",
"Duplication",
"Insertion",
"Inversion",
"Translocation"
],
"description": "Variation in chromosome structure including microscopic and submicroscopic types of variation such as deletions, duplications, copy-number variants, insertions, inversions and translocations."
},
{
"id": 28,
"uri": "http://edamontology.org/topic_0081",
"label": "Structure analysis",
"synonyms": [
"Structural bioinformatics",
"Computational structural biology",
"Structure data resources",
"Molecular structure",
"Structures",
"Structure databases",
"Biomolecular structure"
],
"description": "The curation, processing, analysis and prediction of data about the structure of biological molecules, typically proteins and nucleic acids and other macromolecules."
},
{
"id": 104,
"uri": "http://edamontology.org/topic_0082",
"label": "Structure prediction",
"synonyms": [
"Nucleic acid design",
"Nucleic acid folding",
"RNA structure prediction",
"Protein structure prediction",
"Nucleic acid structure prediction",
"DNA structure prediction",
"Protein fold recognition"
],
"description": "The prediction of molecular structure, including the prediction, modelling, recognition or design of protein secondary or tertiary structure or other structural features, and the folding of nucleic acid molecules and the prediction or design of nucleic acid (typically RNA) sequences with specific conformations."
},
{
"id": 132,
"uri": "http://edamontology.org/topic_3421",
"label": "Surgery",
"synonyms": [
"Transplantation"
],
"description": "The use of operative, manual and instrumental techniques on a patient to investigate and/or treat a pathological condition or help improve bodily function or appearance."
},
{
"id": 79,
"uri": "http://edamontology.org/topic_2259",
"label": "Systems biology",
"synonyms": [
"Biological system modelling",
"Systems modelling",
"Biological modelling"
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"description": "The holistic modelling and analysis of complex biological systems and the interactions therein."
},
{
"id": 9,
"uri": "http://edamontology.org/topic_0637",
"label": "Taxonomy",
"synonyms": null,
"description": "Organism classification, identification and naming."
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{
"id": 120,
"uri": "http://edamontology.org/topic_2840",
"label": "Toxicology",
"synonyms": [
"Toxicoinformatics",
"Computational toxicology"
],
"description": "Toxins and the adverse effects of these chemical substances on living organisms."
},
{
"id": 65,
"uri": "http://edamontology.org/topic_0749",
"label": "Transcription factors and regulatory sites",
"synonyms": [
"Attenuators",
"Transcription factors",
"GC signals",
"Terminators",
"-10 signals",
"TFBS",
"Isochores",
"-35 signals",
"Promoters",
"Enhancers",
"Transcriptional regulatory sites",
"TATA signals",
"CCAAT box",
"Transcription factor binding sites",
"CAAT signals",
"CAT box",
"CpG islands"
],
"description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
},
{
"id": 51,
"uri": "http://edamontology.org/topic_3308",
"label": "Transcriptomics",
"synonyms": [
"Transcriptome",
"Comparative transcriptomics",
"Metatranscriptomics"
],
"description": "The analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc."
},
{
"id": 90,
"uri": "http://edamontology.org/topic_0781",
"label": "Virology",
"synonyms": null,
"description": "Study of viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation."
},
{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
],
"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 49,
"uri": "http://edamontology.org/topic_0769",
"label": "Workflows",
"synonyms": [
"Software integration",
"Pipelines",
"Tool interoperability",
"Tool integration"
],
"description": "Biological or biomedical analytical workflows or pipelines."
},
{
"id": 21,
"uri": "http://edamontology.org/topic_2828",
"label": "X-ray diffraction",
"synonyms": [
"X-ray crystallography",
"X-ray microscopy",
"Crystallography"
],
"description": "The study of matter and their structure by means of the diffraction of X-rays, typically the diffraction pattern caused by the regularly spaced atoms of a crystalline sample."
},
{
"id": 124,
"uri": "http://edamontology.org/topic_3500",
"label": "Zoology",
"synonyms": [
"Animal genetics",
"Animals",
"Entomology",
"Animal",
"Animal biology",
"Metazoa",
"Animal physiology"
],
"description": "Animals, e.g. information on a specific animal genome including molecular sequences, genes and annotation."
}
]
}