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"id": 78,
"uri": "http://edamontology.org/topic_0219",
"label": "Data submission, annotation and curation",
"synonyms": [
"Database curation",
"Data curation",
"Data provenance"
],
"description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
},
{
"id": 121,
"uri": "http://edamontology.org/topic_3343",
"label": "Compound libraries and screening",
"synonyms": [
"Target identification and validation",
"Chemical screening",
"Compound library",
"Chemical library",
"Small compounds libraries",
"Small chemical compounds libraries"
],
"description": "Collections of chemicals, typically for use in high-throughput screening experiments."
},
{
"id": 119,
"uri": "http://edamontology.org/topic_3292",
"label": "Biochemistry",
"synonyms": [
"Glycomics",
"Phytochemistry",
"Biological chemistry",
"Pathobiochemistry"
],
"description": "Chemical substances and physico-chemical processes and that occur within living organisms."
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{
"id": 58,
"uri": "http://edamontology.org/topic_2229",
"label": "Cell biology",
"synonyms": [
"Protein subcellular localization",
"Cellular processes",
"Cells"
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"description": "Cells, such as key genes and proteins involved in the cell cycle."
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{
"id": 49,
"uri": "http://edamontology.org/topic_0769",
"label": "Workflows",
"synonyms": [
"Software integration",
"Pipelines",
"Tool interoperability",
"Tool integration"
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"description": "Biological or biomedical analytical workflows or pipelines."
},
{
"id": 19,
"uri": "http://edamontology.org/topic_3534",
"label": "Protein binding sites",
"synonyms": [
"Protein key folding sites",
"Protein cleavage sites",
"Enzyme active site",
"Protein-nucleic acid binding sites",
"Protein functional sites"
],
"description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
},
{
"id": 126,
"uri": "http://edamontology.org/topic_3474",
"label": "Machine learning",
"synonyms": [
"Kernel methods",
"Active learning",
"Supervised learning",
"Neural networks",
"Knowledge representation",
"Reinforcement learning",
"Ensembl learning",
"Unsupervised learning",
"Recommender system"
],
"description": "A topic concerning the application of artificial intelligence methods to algorithms, in order to create methods that can learn from data in order to generate an ouput, rather than relying on explicitly encoded information only."
},
{
"id": 13,
"uri": "http://edamontology.org/topic_3170",
"label": "RNA-Seq",
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"RNA sequencing",
"RNA-Seq analysis",
"Whole transcriptome shotgun sequencing",
"WTSS",
"Small-Seq",
"Small RNA sequencing",
"Small RNA-Seq",
"miRNA-seq",
"MicroRNA sequencing",
"Transcriptome profiling"
],
"description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
},
{
"id": 80,
"uri": "http://edamontology.org/topic_0621",
"label": "Model organisms",
"synonyms": [
"Organisms"
],
"description": "A specific organism, or group of organisms, used to study a particular aspect of biology."
},
{
"id": 74,
"uri": "http://edamontology.org/topic_0078",
"label": "Proteins",
"synonyms": [
"Protein informatics",
"Protein bioinformatics",
"Protein databases"
],
"description": "Archival, processing and analysis of protein data, typically molecular sequence and structural data."
},
{
"id": 124,
"uri": "http://edamontology.org/topic_3500",
"label": "Zoology",
"synonyms": [
"Animal genetics",
"Animals",
"Entomology",
"Animal",
"Animal biology",
"Metazoa",
"Animal physiology"
],
"description": "Animals, e.g. information on a specific animal genome including molecular sequences, genes and annotation."
},
{
"id": 89,
"uri": "http://edamontology.org/topic_3957",
"label": "Protein interaction experiment",
"synonyms": [
"Phage display",
"Yeast one-hybrid",
"Co-immunoprecipitation",
"Yeast two-hybrid"
],
"description": "An experiment for studying protein-protein interactions."
},
{
"id": 135,
"uri": "http://edamontology.org/topic_3577",
"label": "Personalised medicine",
"synonyms": [
"Precision medicine",
"Molecular diagnostics"
],
"description": "An approach to medicine whereby decisions, practices and are tailored to the individual patient based on their predicted response or risk of disease."
},
{
"id": 32,
"uri": "http://edamontology.org/topic_0593",
"label": "NMR",
"synonyms": [
"Nuclear Overhauser Effect Spectroscopy",
"Rotational Frame Nuclear Overhauser Effect Spectroscopy",
"ROESY",
"Nuclear magnetic resonance spectroscopy",
"NOESY",
"NMR spectroscopy",
"Heteronuclear Overhauser Effect Spectroscopy",
"HOESY"
],
"description": "An analytical technique that exploits the magenetic properties of certain atomic nuclei to provide information on the structure, dynamics, reaction state and chemical environment of molecules."
},
{
"id": 36,
"uri": "http://edamontology.org/topic_3930",
"label": "Immunogenetics",
"synonyms": [
"Immune system genetics",
"Immunology and genetics",
"Immunogenes",
"Immungenetics"
],
"description": "A biomedical field that bridges immunology and genetics, to study the genetic basis of the immune system."
},
{
"id": 127,
"uri": "https://edamontology.org/topic_3308",
"label": "",
"synonyms": null,
"description": ""
}
]
}