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{
"count": 140,
"next": null,
"previous": "https://catalogue.france-bioinformatique.fr/api/topic/?format=api&limit=20&offset=100",
"results": [
{
"id": 68,
"uri": "http://edamontology.org/topic_0194",
"label": "Phylogenomics",
"synonyms": null,
"description": "The integrated study of evolutionary relationships and whole genome data, for example, in the analysis of species trees, horizontal gene transfer and evolutionary reconstruction."
},
{
"id": 88,
"uri": "http://edamontology.org/topic_0091",
"label": "Bioinformatics",
"synonyms": null,
"description": "The archival, curation, processing and analysis of complex biological data."
},
{
"id": 51,
"uri": "http://edamontology.org/topic_3308",
"label": "Transcriptomics",
"synonyms": [
"Transcriptome",
"Comparative transcriptomics",
"Metatranscriptomics"
],
"description": "The analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc."
},
{
"id": 57,
"uri": "http://edamontology.org/topic_3064",
"label": "Developmental biology",
"synonyms": [
"Development"
],
"description": "How organisms grow and develop."
},
{
"id": 79,
"uri": "http://edamontology.org/topic_2259",
"label": "Systems biology",
"synonyms": [
"Biological system modelling",
"Systems modelling",
"Biological modelling"
],
"description": "The holistic modelling and analysis of complex biological systems and the interactions therein."
},
{
"id": 89,
"uri": "http://edamontology.org/topic_3957",
"label": "Protein interaction experiment",
"synonyms": [
"Phage display",
"Yeast one-hybrid",
"Co-immunoprecipitation",
"Yeast two-hybrid"
],
"description": "An experiment for studying protein-protein interactions."
},
{
"id": 107,
"uri": "http://edamontology.org/topic_3372",
"label": "Software engineering",
"synonyms": [
"Computer programming",
"Algorithms",
"Software development",
"Data structures",
"Programming languages"
],
"description": "The process that leads from an original formulation of a computing problem to executable programs."
},
{
"id": 24,
"uri": "http://edamontology.org/topic_0128",
"label": "Protein interactions",
"synonyms": [
"Protein interaction networks",
"Protein-ligand interactions",
"Protein-nucleic acid interactions",
"Protein-DNA interactions",
"Protein-DNA interaction",
"Protein interaction map",
"Protein-RNA interaction",
"Protein-RNA interactions",
"Protein interactome",
"Protein-protein interactions"
],
"description": "Protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions."
},
{
"id": 55,
"uri": "http://edamontology.org/topic_0089",
"label": "Ontology and terminology",
"synonyms": [
"Upper ontology",
"Terminology",
"Ontology",
"Ontologies",
"Ontology relations",
"Applied ontology"
],
"description": "The conceptualisation, categorisation and nomenclature (naming) of entities or phenomena within biology or bioinformatics. This includes formal ontologies, controlled vocabularies, structured glossary, symbols and terminology or other related resource."
},
{
"id": 14,
"uri": "http://edamontology.org/topic_2269",
"label": "Statistics and probability",
"synonyms": [
"Biostatistics",
"Multivariate statistics",
"Bayesian methods",
"Gaussian processes",
"Probability",
"Markov processes",
"Probabilistic graphical model",
"Inferential statistics",
"Descriptive statistics",
"Statistics"
],
"description": "The application of statistical methods to biological problems."
},
{
"id": 85,
"uri": "http://edamontology.org/topic_0610",
"label": "Ecology",
"synonyms": [
"Ecological informatics",
"Ecoinformatics",
"Ecosystem science",
"Computational ecology"
],
"description": "The ecological and environmental sciences and especially the application of information technology (ecoinformatics)."
},
{
"id": 12,
"uri": "http://edamontology.org/topic_0102",
"label": "Mapping",
"synonyms": [
"Linkage",
"Synteny",
"Genetic linkage",
"Linkage mapping"
],
"description": "The mapping of complete (typically nucleotide) sequences. Mapping (in the sense of short read alignment, or more generally, just alignment) has application in RNA-Seq analysis (mapping of transcriptomics reads), variant discovery (e.g. mapping of exome capture), and re-sequencing (mapping of WGS reads)."
},
{
"id": 77,
"uri": "http://edamontology.org/topic_0602",
"label": "Molecular interactions, pathways and networks",
"synonyms": [
"Networks",
"Gene regulatory networks",
"Interactome",
"Molecular interactions",
"Disease pathways",
"Biological pathways",
"Signaling pathways",
"Pathways",
"Environmental information processing pathways",
"Cellular process pathways",
"Genetic information processing pathways",
"Signal transduction pathways",
"Biological models",
"Metabolic pathways",
"Biological networks",
"Interactions"
],
"description": "Molecular interactions, biological pathways, networks and other models."
},
{
"id": 65,
"uri": "http://edamontology.org/topic_0749",
"label": "Transcription factors and regulatory sites",
"synonyms": [
"Attenuators",
"Transcription factors",
"GC signals",
"Terminators",
"-10 signals",
"TFBS",
"Isochores",
"-35 signals",
"Promoters",
"Enhancers",
"Transcriptional regulatory sites",
"TATA signals",
"CCAAT box",
"Transcription factor binding sites",
"CAAT signals",
"CAT box",
"CpG islands"
],
"description": "Proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences."
},
{
"id": 138,
"uri": "http://edamontology.org/topic_3295",
"label": "Epigenetics",
"synonyms": [
"DNA methylation",
"Histone modification",
"Methylation profiles"
],
"description": "Topic concerning the study of heritable changes, for example in gene expression or phenotype, caused by mechanisms other than changes in the DNA sequence."
},
{
"id": 137,
"uri": "http://edamontology.org/topic_3796",
"label": "Population genomics",
"synonyms": [],
"description": "Large-scale study (typically comparison) of DNA sequences of populations."
},
{
"id": 70,
"uri": "http://edamontology.org/topic_0623",
"label": "Gene and protein families",
"synonyms": [
"Gene system",
"Gene families",
"Gene family",
"Protein sequence classification",
"Protein families",
"Genes, gene family or system"
],
"description": "Particular gene(s), gene family or other gene group or system and their encoded proteins.Primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group."
},
{
"id": 84,
"uri": "http://edamontology.org/topic_3810",
"label": "Agricultural science",
"synonyms": [
"",
"Plant pathology",
"Animal nutrition",
"Agricultural biotechnology",
"Horticulture",
"Animal husbandry",
"Agricultural economics",
"Phytomedicine",
"Food process engineering",
"Plant breeding",
"Animal breeding",
"Farming systems research",
"Plant nutrition",
"Food security",
"Soil science",
"Plant cultivation"
],
"description": "Multidisciplinary study, research and development within the field of agriculture."
},
{
"id": 140,
"uri": "http://edamontology.org/topic_3345",
"label": "Data identity and mapping",
"synonyms": [],
"description": "Topic concerning the identity of biological entities, or reports on such entities, and the mapping of entities and records in different databases."
},
{
"id": 139,
"uri": "http://edamontology.org/topic_4012",
"label": "FAIR data",
"synonyms": [
"Findable, accessible, interoperable, reusable data",
"Open data"
],
"description": "FAIR data is scientific data that meets the principles of being findable, accessible, interoperable, and reusable."
}
]
}