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"id": 7,
"uri": "http://edamontology.org/topic_3489",
"label": "Database management",
"synonyms": [
"Content management",
"Document, record and content management",
"Record management",
"Data maintenance",
"File management",
"Database administration",
"Document management"
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"description": "The general handling of data stored in digital archives such as databanks, databases proper, web portals and other data resources."
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{
"id": 124,
"uri": "http://edamontology.org/topic_3500",
"label": "Zoology",
"synonyms": [
"Animal genetics",
"Animals",
"Entomology",
"Animal",
"Animal biology",
"Metazoa",
"Animal physiology"
],
"description": "Animals, e.g. information on a specific animal genome including molecular sequences, genes and annotation."
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{
"id": 50,
"uri": "http://edamontology.org/topic_3510",
"label": "Protein sites, features and motifs",
"synonyms": [
"Protein sequence features",
"Signal peptide cleavage sites"
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"description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in protein sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 66,
"uri": "http://edamontology.org/topic_3511",
"label": "Nucleic acid sites, features and motifs",
"synonyms": [
"Nucleic acid functional sites",
"Primer binding sites",
"Nucleic acid sequence features",
"Sequence tagged sites"
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"description": "The biology, archival, detection, prediction and analysis of positional features such as functional and other key sites, in nucleic acid sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them."
},
{
"id": 26,
"uri": "http://edamontology.org/topic_3512",
"label": "Gene transcripts",
"synonyms": [
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"Introns",
"PolyA site",
"EST",
"Gene transcript features",
"Transit peptide coding sequence",
"mRNA",
"Fusion transcripts",
"Coding RNA",
"PolyA signal",
"mRNA features",
"cDNA",
"Signal peptide coding sequence"
],
"description": "Transcription of DNA into RNA and features of a messenger RNA (mRNA) molecules including precursor RNA, primary (unprocessed) transcript and fully processed molecules."
},
{
"id": 15,
"uri": "http://edamontology.org/topic_3517",
"label": "GWAS study",
"synonyms": [
"GWAS",
"Genome-wide association study",
"GWAS analysis"
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"description": "Genome-wide association study experiments."
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{
"id": 98,
"uri": "http://edamontology.org/topic_3518",
"label": "Microarray experiment",
"synonyms": [
"miRNA array",
"Proprietary platform micoarray",
"MicroRNA array",
"Gene expression microarray",
"Multichannel microarray",
"RNA microarrays",
"Microarrays",
"mRNA microarray",
"Reverse phase protein array",
"One channel microarray",
"aCGH microarray",
"Tissue microarray",
"SNP array",
"Methylation array",
"Tiling arrays",
"RNA chips",
"Genotyping array",
"Two channel microarray"
],
"description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
},
{
"id": 2,
"uri": "http://edamontology.org/topic_3519",
"label": "PCR experiment",
"synonyms": [
"Polymerase chain reaction",
"Real Time Quantitative PCR",
"RT-qPCR",
"Quantitative PCR"
],
"description": "PCR experiments, e.g. quantitative real-time PCR."
},
{
"id": 106,
"uri": "http://edamontology.org/topic_3520",
"label": "Proteomics experiment",
"synonyms": [
"2D PAGE experiment",
"Spectrum demultiplexing",
"Mass spectrometry experiments",
"MS",
"Northern blot experiment",
"MS experiments",
"DIA",
"Mass spectrometry",
"Data-independent acquisition"
],
"description": "Proteomics experiments."
},
{
"id": 108,
"uri": "http://edamontology.org/topic_3523",
"label": "RNAi experiment",
"synonyms": null,
"description": "RNAi experiments."
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{
"id": 19,
"uri": "http://edamontology.org/topic_3534",
"label": "Protein binding sites",
"synonyms": [
"Protein key folding sites",
"Protein cleavage sites",
"Enzyme active site",
"Protein-nucleic acid binding sites",
"Protein functional sites"
],
"description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
},
{
"id": 116,
"uri": "http://edamontology.org/topic_3542",
"label": "Protein secondary structure",
"synonyms": [
"Protein super-secondary structure",
"Protein features (secondary structure)"
],
"description": "Secondary structure (predicted or real) of a protein, including super-secondary structure."
},
{
"id": 94,
"uri": "http://edamontology.org/topic_3571",
"label": "Data governance",
"synonyms": [
"Data stewardship"
],
"description": "The control of data entry and maintenance to ensure the data meets defined standards, qualities or constraints."
},
{
"id": 5,
"uri": "http://edamontology.org/topic_3572",
"label": "Data quality management",
"synonyms": [
"Data integrity",
"Data cleaning",
"Data quality",
"Data clean-up"
],
"description": "The quality, integrity, and cleaning up of data."
},
{
"id": 95,
"uri": "http://edamontology.org/topic_3574",
"label": "Human genetics",
"synonyms": null,
"description": "The study of inheritance in human beings."
},
{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
],
"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 123,
"uri": "http://edamontology.org/topic_3676",
"label": "Exome sequencing",
"synonyms": [
"Exome",
"Exome capture",
"WES",
"Whole exome sequencing",
"Targeted exome capture",
"Exome analysis"
],
"description": "Laboratory technique to sequence all the protein-coding regions in a genome, i.e., the exome."
},
{
"id": 109,
"uri": "http://edamontology.org/topic_3678",
"label": "Experimental design and studies",
"synonyms": [
"Studies",
"Experimental design",
"Design of experiments"
],
"description": "The design of an experiment intended to test a hypothesis, and describe or explain empirical data obtained under various experimental conditions."
},
{
"id": 52,
"uri": "http://edamontology.org/topic_3679",
"label": "Animal study",
"synonyms": [
"Challenge study"
],
"description": "The design of an experiment involving non-human animals."
},
{
"id": 1,
"uri": "http://edamontology.org/topic_3697",
"label": "Microbial ecology",
"synonyms": [
"Molecular community analysis",
"Community analysis",
"Microbiome",
"Environmental microbiology"
],
"description": "The ecology of microorganisms including their relationship with one another and their environment."
}
]
}