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"id": 77,
"uri": "http://edamontology.org/topic_0602",
"label": "Molecular interactions, pathways and networks",
"synonyms": [
"Networks",
"Gene regulatory networks",
"Interactome",
"Molecular interactions",
"Disease pathways",
"Biological pathways",
"Signaling pathways",
"Pathways",
"Environmental information processing pathways",
"Cellular process pathways",
"Genetic information processing pathways",
"Signal transduction pathways",
"Biological models",
"Metabolic pathways",
"Biological networks",
"Interactions"
],
"description": "Molecular interactions, biological pathways, networks and other models."
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{
"id": 3,
"uri": "http://edamontology.org/topic_0798",
"label": "Mobile genetic elements",
"synonyms": [
"Transposons"
],
"description": "Mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns."
},
{
"id": 98,
"uri": "http://edamontology.org/topic_3518",
"label": "Microarray experiment",
"synonyms": [
"miRNA array",
"Proprietary platform micoarray",
"MicroRNA array",
"Gene expression microarray",
"Multichannel microarray",
"RNA microarrays",
"Microarrays",
"mRNA microarray",
"Reverse phase protein array",
"One channel microarray",
"aCGH microarray",
"Tissue microarray",
"SNP array",
"Methylation array",
"Tiling arrays",
"RNA chips",
"Genotyping array",
"Two channel microarray"
],
"description": "Microarray experiments including conditions, protocol, sample:data relationships etc."
},
{
"id": 101,
"uri": "http://edamontology.org/topic_3673",
"label": "Whole genome sequencing",
"synonyms": [
"De novo genome sequencing",
"WGS",
"Genome sequencing",
"Whole genome resequencing"
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"description": "Laboratory technique to sequence the complete DNA sequence of an organism's genome at a single time."
},
{
"id": 123,
"uri": "http://edamontology.org/topic_3676",
"label": "Exome sequencing",
"synonyms": [
"Exome",
"Exome capture",
"WES",
"Whole exome sequencing",
"Targeted exome capture",
"Exome analysis"
],
"description": "Laboratory technique to sequence all the protein-coding regions in a genome, i.e., the exome."
},
{
"id": 37,
"uri": "http://edamontology.org/topic_3948",
"label": "Immunoinformatics",
"synonyms": [
"Computational immunology"
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"description": "Immunoinformatics is the field of computational biology that deals with the study of immunoloogical questions. Immunoinformatics is at the interface between immunology and computer science. It takes advantage of computational, statistical, mathematical approaches and enhances the understanding of immunological knowledge."
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{
"id": 57,
"uri": "http://edamontology.org/topic_3064",
"label": "Developmental biology",
"synonyms": [
"Development"
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"description": "How organisms grow and develop."
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{
"id": 15,
"uri": "http://edamontology.org/topic_3517",
"label": "GWAS study",
"synonyms": [
"GWAS",
"Genome-wide association study",
"GWAS analysis"
],
"description": "Genome-wide association study experiments."
},
{
"id": 117,
"uri": "http://edamontology.org/topic_0114",
"label": "Gene structure",
"synonyms": [
"Fusion genes",
"Gene features"
],
"description": "Gene structure, regions which make an RNA product and features such as promoters, coding regions, gene fusion, splice sites etc."
},
{
"id": 40,
"uri": "http://edamontology.org/topic_0654",
"label": "DNA",
"synonyms": [
"Ancient DNA",
"DNA analysis",
"Chromosomes"
],
"description": "DNA sequences and structure, including processes such as methylation and replication."
},
{
"id": 4,
"uri": "http://edamontology.org/topic_2885",
"label": "DNA polymorphism",
"synonyms": [
"Microsatellites",
"SNP",
"Variable number of tandem repeat polymorphism",
"snps",
"Single nucleotide polymorphism",
"VNTR",
"RFLP"
],
"description": "DNA polymorphism."
},
{
"id": 96,
"uri": "http://edamontology.org/topic_0634",
"label": "Pathology",
"synonyms": [
"Pathology",
"Disease"
],
"description": "Diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases."
},
{
"id": 78,
"uri": "http://edamontology.org/topic_0219",
"label": "Data submission, annotation and curation",
"synonyms": [
"Database curation",
"Data curation",
"Data provenance"
],
"description": "Deposition and curation of database accessions, including annotation, typically with terms from a controlled vocabulary."
},
{
"id": 121,
"uri": "http://edamontology.org/topic_3343",
"label": "Compound libraries and screening",
"synonyms": [
"Target identification and validation",
"Chemical screening",
"Compound library",
"Chemical library",
"Small compounds libraries",
"Small chemical compounds libraries"
],
"description": "Collections of chemicals, typically for use in high-throughput screening experiments."
},
{
"id": 119,
"uri": "http://edamontology.org/topic_3292",
"label": "Biochemistry",
"synonyms": [
"Glycomics",
"Phytochemistry",
"Biological chemistry",
"Pathobiochemistry"
],
"description": "Chemical substances and physico-chemical processes and that occur within living organisms."
},
{
"id": 58,
"uri": "http://edamontology.org/topic_2229",
"label": "Cell biology",
"synonyms": [
"Protein subcellular localization",
"Cellular processes",
"Cells"
],
"description": "Cells, such as key genes and proteins involved in the cell cycle."
},
{
"id": 49,
"uri": "http://edamontology.org/topic_0769",
"label": "Workflows",
"synonyms": [
"Software integration",
"Pipelines",
"Tool interoperability",
"Tool integration"
],
"description": "Biological or biomedical analytical workflows or pipelines."
},
{
"id": 19,
"uri": "http://edamontology.org/topic_3534",
"label": "Protein binding sites",
"synonyms": [
"Protein key folding sites",
"Protein cleavage sites",
"Enzyme active site",
"Protein-nucleic acid binding sites",
"Protein functional sites"
],
"description": "Binding sites in proteins, including cleavage sites (for a proteolytic enzyme or agent), key residues involved in protein folding, catalytic residues (active site) of an enzyme, ligand-binding (non-catalytic) residues of a protein, such as sites that bind metal, prosthetic groups or lipids, RNA and DNA-binding proteins and binding sites etc."
},
{
"id": 126,
"uri": "http://edamontology.org/topic_3474",
"label": "Machine learning",
"synonyms": [
"Kernel methods",
"Active learning",
"Supervised learning",
"Neural networks",
"Knowledge representation",
"Reinforcement learning",
"Ensembl learning",
"Unsupervised learning",
"Recommender system"
],
"description": "A topic concerning the application of artificial intelligence methods to algorithms, in order to create methods that can learn from data in order to generate an ouput, rather than relying on explicitly encoded information only."
},
{
"id": 13,
"uri": "http://edamontology.org/topic_3170",
"label": "RNA-Seq",
"synonyms": [
"RNA sequencing",
"RNA-Seq analysis",
"Whole transcriptome shotgun sequencing",
"WTSS",
"Small-Seq",
"Small RNA sequencing",
"Small RNA-Seq",
"miRNA-seq",
"MicroRNA sequencing",
"Transcriptome profiling"
],
"description": "A topic concerning high-throughput sequencing of cDNA to measure the RNA content (transcriptome) of a sample, for example, to investigate how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions."
}
]
}