Team List
Handles creating, reading and updating teams.
GET /api/team/?format=api&offset=20&ordering=ifbMembership
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Grâce au projet CeSGO, GenOuest propose un ensemble d'outils collaboratifs pour gérer au mieux les projets et les données scientifiques. GenOuest développe des applications bio-informatiques ainsi que la formation et le transfert technologique de nouveaux outils développés par les équipes de recherche de l'Institut.", "expertise": [ "http://edamontology.org/topic_3372", "http://edamontology.org/topic_0605", "http://edamontology.org/topic_3071", "http://edamontology.org/topic_0091", "http://edamontology.org/topic_3571" ], "expertise_description": "Gestion FAIR des données et logiciels, environnements d'analyse et de calcul (ligne de commande, cloud, packaging, containers), portail web d'analyse de données Galaxy", "linkCovid19": "", "homepage": "https://www.genouest.org/", "unitId": "UMR6074", "address": "IRISA-INRIA \r\nCampus de Beaulieu\r\n263 avenue du Général Leclerc", "city": "Rennes", "country": "France", "communities": [], "projects": [ "https://catalogue.france-bioinformatique.fr/api/project/ELIXIR-CONVERGE/?format=api", "https://catalogue.france-bioinformatique.fr/api/project/ELIXIR-BIOCONTAINERS/?format=api" ], "affiliatedWith": [ { "id": 75, "name": "Inria Rennes - Bretagne Atlantique Research Centre", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Inria%20Rennes%20-%20Bretagne%20Atlantique%20Research%20Centre/?format=api" }, { "id": 78, "name": "IRISA", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/IRISA/?format=api" } ], "publications": [ "10.3390/IECE-10646", "10.1021/acs.jproteome.0c00904", "10.1186/s12915-020-00820-5", "10.1186/s13059-019-1772-6", "" ], "certifications": [ "Label IBiSA" ], "fundedBy": [ { "id": 8, "name": "Elixir", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Elixir/?format=api" }, { "id": 61, "name": "INRIA", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INRIA/?format=api" }, { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" } ], "keywords": [ "HPC", "Programming Languages & Computer Sciences", "Cloud", "Biodiversity", "GPU" ], "fields": [ "Biologie", "Biomédical", "Agro-alimentaire", "Environnement", "Biotechnologie" ], "orgid": null, "tools": [ "aphidbase", "askomics", "aureme", "autograph", "biomaj", "commet", "discosnp", "", "germonline", "gatb", "lepidodb", "logol", "mindthegap", "minia", "peppsy", "protomata", "rasta-bacteria", "reprogenomics_viewer" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/805/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/77/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/77/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/529/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/427/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/497/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/77/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "48.116255", "lng": "-1.638920", "updated_at": "2025-12-09T09:59:51.778066Z" }, { "id": 6, "name": "CBiB", "logo_url": "https://services.cbib.u-bordeaux.fr/utils/logo_cbib.png", "description": "The Bordeaux Bioinformatics Centre (CBiB) is a technology platform specialized in the analysis of high-throughput biological data (genomics, transcriptomics, proteomics, metabolomics, imaging). With strong expertise and the integration of advanced technologies, including artificial intelligence, CBiB supports academic and industrial partners in extracting value from complex data. Its services cover the full data lifecycle, supported by high-performance infrastructures and a multidisciplinary team in bioinformatics.", "expertise": [ "http://edamontology.org/topic_3391", "http://edamontology.org/topic_3517", "http://edamontology.org/topic_3941", "http://edamontology.org/topic_0121", "http://edamontology.org/topic_0203", "http://edamontology.org/topic_0196", "http://edamontology.org/topic_0080", "http://edamontology.org/topic_0091", "http://edamontology.org/topic_3307" ], "expertise_description": "soon", "linkCovid19": "", "homepage": "https://www.cbib.u-bordeaux.fr/", "unitId": "", "address": "146 Rue Léo Saignat\r\n33076 Bordeaux\r\nFrance", "city": "Bordeaux", "country": "France", "communities": [], "projects": [], "affiliatedWith": [], "publications": [ "", "10.1093/eep/dvac022", "10.1017/S2633903X22000034", "10.3389/fbinf.2022.867111", "10.3389/fbinf.2022.999700", "10.15252/emmm.202115343", "10.1016/j.jhazmat.2023.131579", "10.1080/15592294.2023.2260963", "10.3390/ijms24119724", "10.5220/0011623500003414", "10.1128/spectrum.02251-22", "10.1021/acschembio.3c00440", "10.1038/s43018-023-00717-6", "10.1093/bioinformatics/btae282", "10.1038/s44321-025-00195-6", "10.1016/j.celrep.2024.113773", "10.1093/bioadv/vbae081", "10.1016/j.jgar.2024.12.006", "10.48550/arXiv.2505.08508", "10.1128/mbio.01360-24" ], "certifications": [ "Label IBiSA", "ISO 9001", "CNOC (INRA)", "NF X50-900" ], "fundedBy": [ { "id": 91, "name": "University of Bordeaux", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/University%20of%20Bordeaux/?format=api" } ], "keywords": [ "Artificial Intelligence", "cancer", "Image analysis", "spatial transcriptomics", "Metabolomics", "proteomics", "Integration of heterogeneous data", "Single-Cell Analysis", "Comparative genomics", "NGS Sequencing Data Analysis" ], "fields": [ "Biologie", "Biomédical", "Agro-alimentaire", "Environnement" ], "orgid": "057qpr032", "tools": [ "xeml-lab", "mix", "molligen", "tango", "xheinz" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/467/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/268/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/268/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/34/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/154/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/467/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/34/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/268/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/154/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "44.824860", "lng": "-0.608450", "updated_at": "2025-12-09T14:21:19.010919Z" }, { "id": 11, "name": "Pasteur HUB", "logo_url": "https://hub-portal.pasteur.cloud/logo-hub.png", "description": "Le centre de bioinformatique et de biostatistique est la partie service du département de biologie informatique. L’équipe du Hub comprend 50 experts en biostatistique et en bioinformatique. Créé en 2015, le C3BI comprend cinq unités de recherche en biologie computationnelle et le Hub de bioinformatique et biostatistique. La mission du centre est de développer la recherche méthodologique en bioinformatique et biostatistique, de donner une visibilité internationale à l'Institut Pasteur dans ce domaine, d'offrir un soutien aux unités de recherche expérimentale, et de développer les compétences informatiques et analytiques du campus. Les activités de la plateforme comprennent la participation à des projets de recherche et d'analyse, des missions sur le terrain au sein des unités et des plateformes du campus, des sessions de formation et d'enseignement ouvertes à nos partenaires, et fournissent un certain nombre de ressources à la communauté nationale et internationale. L’équipe du Hub et l’ensemble du département ont une longue expérience dans le développement de sites web (par exemple NGPhylogeny.fr), les calculs intensifs et la gestion des données de santé.", "expertise": [ "http://edamontology.org/topic_3372" ], "expertise_description": "", "linkCovid19": "", "homepage": "https://research.pasteur.fr/en/team/bioinformatics-and-biostatistics-hub/", "unitId": "", "address": "25 Rue du Dr Roux", "city": "Paris", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 48, "name": "Institut Pasteur", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Institut%20Pasteur/?format=api" } ], "publications": [ "10.21105/joss.00698", "10.1093/bioinformatics/btab070", "" ], "certifications": [], "fundedBy": [ { "id": 48, "name": "Institut Pasteur", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Institut%20Pasteur/?format=api" } ], "keywords": [], "fields": [ "Biologie", "Biomédical" ], "orgid": null, "tools": [ "edam-browser", "fqtools", "macsyfinder", "memhdx", "sartools", "shaman", "syntview", "VHRdb" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/432/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/432/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/251/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/461/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/73/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/432/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/184/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/408/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/414/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/379/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/432/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/73/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "48.840351", "lng": "2.310813", "updated_at": "2025-10-21T13:07:13.054323Z" }, { "id": 16, "name": "BiRD", "logo_url": "https://pf-bird.univ-nantes.fr/images/logo/logo.svg", "description": "BiRD brings together life-science and digital-science research laboratories in Nantes. It supports researchers in managing, integrating, analyzing, and modeling experimental data by providing large-scale storage and computing infrastructure, as well as (bio)informatics tools, standardized analysis pipelines, and training. By pooling human resources, expertise, software, and datasets, BiRD aims to strengthen and sustain bio-analysis capabilities, facilitate the analysis and reuse of heterogeneous data, scale up methods developed by partner teams, and contribute to training in life and digital sciences.", "expertise": [], "expertise_description": "BiRD offers expertise in genetics, transcriptomics, single-cell and metagenomic analyses, alongside knowledge-graph development, supporting research in cancer, immunology, cardiovascular and metabolic diseases through advanced bioinformatic workflows and large-scale data processing.", "linkCovid19": "", "homepage": "http://pf-bird.univ-nantes.fr/", "unitId": "", "address": "IRS UN, 8 Quai Moncousu", "city": "Nantes", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 31, "name": "Institut du Thorax", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Institut%20du%20Thorax/?format=api" }, { "id": 112, "name": "LS2N", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/LS2N/?format=api" } ], "publications": [ "" ], "certifications": [ "Label IBiSA" ], "fundedBy": [ { "id": 56, "name": "INSERM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INSERM/?format=api" }, { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 114, "name": "Nantes Université", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Nantes%20Universit%C3%A9/?format=api" } ], "keywords": [ "NGS Data Analysis", "Metagenomics", "Metabolic Network Modelling", "Ontologies", "Transcriptomics", "Variant analysis", "Interoperability", "Integration of heterogeneous data", "Knowledge representation", "Workflow development" ], "fields": [ "Biologie", "Biomédical", "Informatique" ], "orgid": null, "tools": [ "3SRP", "DEPIB", "fair-checker", "magneto", "mibiomics", "microSysMics", "pybravo" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/69/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/520/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/54/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/237/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/596/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/69/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/54/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/106/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/279/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/520/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/237/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/54/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "47.209985", "lng": "-1.553544", "updated_at": "2026-01-07T12:57:08.816204Z" }, { "id": 7, "name": "ATGC", "logo_url": "https://www.lirmm.fr/wp-content/uploads/sites/3/2025/11/ATGClogo_LIRMM-300x105-1.jpg", "description": "The bioinformatics platform ATGC is supported by a research team from LIRMM. It has the triple vocation of disseminating the bioinformatics tools developed within the Montpellier community, of encouraging collaborations between computer scientists and biologists, and of providing assistance to these researchers by setting up bioinformatics services directly related to their work. The tools it offers are accessible online free of charge. They can be downloaded and/or run on Cluster IO from Montpellier Mésocentre (ISDM). A major axis of the platform concerns evolutionary studies.", "expertise": [ "http://edamontology.org/topic_3372" ], "expertise_description": "The ATGC platform aims to braodcast the software systems developed by MAB Team from LIRMM.\r\nThe MAB team (Methods and Algorithms for Bioinformatics) proposes mathematical and algorithmic methods (text and tree algorithms, combinatorial algorithms and optimization, probabilistic modeling, statistical machine learning) to address biological issues such as evolution, phylogeny, comparative genomics", "linkCovid19": "", "homepage": "http://www.atgc-montpellier.fr/", "unitId": "UMR5506", "address": "860 rue Saint Priest", "city": "Montpellier", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 73, "name": "LIRMM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/LIRMM/?format=api" } ], "publications": [ "10.1007/978-3-642-00982-2_60", "10.1186/1471-2105-9-166", "10.1093/sysbio/syq002", "10.1093/oxfordjournals.molbev.a025808", "10.1080/10635150390235520", "10.1093/nar/gki352", "10.1093/bioinformatics/bti713", "10.1080/10635150600755453", "10.1080/10635150701639754", "10.1093/molbev/msn067", "10.1098/rstb.2008.0180", "10.1186/1471-2105-9-413", "10.1080/10635150600969872", "", "10.1093/sysbio/syq010", "10.1093/nar/gkn180" ], "certifications": [ "Label IBiSA" ], "fundedBy": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 99, "name": "University of Montpellier", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/University%20of%20Montpellier/?format=api" } ], "keywords": [ "Phylogeny", "Evolution and Phylogeny", "Text mining", "Structural genomics" ], "fields": [ "Biologie", "Biomédical", "Agro-alimentaire", "Environnement", "Biotechnologie" ], "orgid": null, "tools": [ "bionj", "compphy", "crac", "fastme", "lordec", "mpscan", "phylogeny.fr", "phyml" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/528/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/282/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/830/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/528/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/443/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/50/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/76/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/108/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/118/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/282/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/411/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/480/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/585/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/443/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/830/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "43.636878", "lng": "3.841811", "updated_at": "2025-11-27T13:24:55.215918Z" }, { "id": 30, "name": "Inforbio", "logo_url": "https://www.ibps.sorbonne-universite.fr/ressources/images/129/2643,200x,logoInforBio_fond_blanc.png", "description": "The InforBio bioinformatics platform provides support and an environment for the analysis of high-throughput sequencing data. We specialize primarily in the analysis of epigenetic data (ChIP-Seq) and RNA sequencing, including bulk RNA-Seq, single-cell RNA-Seq, and spatial tanscriptomics.\r\n\r\nWe offer our services through scientific services and collaborations, including joint funding requests with partner teams. We develop online analysis pipelines via Galaxy and offer specialized long-term support (IOC program).\r\n\r\nTo facilitate analysis and programming, we provide online tools for statistics (RStudio) and programming (Jupyter), as well as a 1 Petabyte data storage server.", "expertise": [ "http://edamontology.org/topic_3173", "http://edamontology.org/topic_3170", "http://edamontology.org/topic_0769", "http://edamontology.org/topic_3308", "http://edamontology.org/topic_3474" ], "expertise_description": "We specialize in advanced transcriptomic analysis complemented by epigenetic studies.\r\n\r\n\r\nOur core capabilities encompass the entire data processing workflow, from high-performance sequence alignment and differential expression analysis to sophisticated multivariate analyses for comprehensive biological insight.", "linkCovid19": "", "homepage": "https://inforbio.github.io/", "unitId": "", "address": "Plateforme de bioinformatique ARTbio\r\nIBPS & Sorbonne Université \r\nBâtiment B, 7ème étage, porte 725.\r\n9, Quai St Bernard, \r\nBoîte courrier 25", "city": "Paris Cedex 05", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 110, "name": "Sorbonne Université", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Sorbonne%20Universit%C3%A9/?format=api" } ], "publications": [ "" ], "certifications": [], "fundedBy": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 110, "name": "Sorbonne Université", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/Sorbonne%20Universit%C3%A9/?format=api" } ], "keywords": [ "Biostatistics", "Epigenetics", "spatial transcriptomics", "Bioinformatics", "Galaxy", "Transcriptomics", "Single-Cell Analysis" ], "fields": [], "orgid": null, "tools": [], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/809/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/808/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/858/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/808/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "48.846891", "lng": "2.359061", "updated_at": "2025-12-09T10:03:58.367591Z" }, { "id": 24, "name": "South Green", "logo_url": "https://southgreenplatform.github.io/trainings//images/southgreenlong.png", "description": "South Green is a bioinformatics platform dedicated to the genomics of tropical and Mediterranean plants and their associated pathogens. It brings together bioinformaticians from several units and institutes in Montpellier (CIRAD, INRAE, IRD, and the Alliance Bioversity International and CIAT), who have multidisciplinary expertise in data integration, software development, sequencing data analysis, and high-performance computing. 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It offers databases and tools along three axes: genomics, the expressed repertoire, and proteins (including crystallographic structure).", "linkCovid19": "", "homepage": "https://www.imgt.org/", "unitId": "", "address": "Faculté de Pharmacie, \r\n15 avenue Charles Flahault", "city": "Montpellier Cede 5", "country": "France", "communities": [], "projects": [], "affiliatedWith": [], "publications": [ "" ], "certifications": [], "fundedBy": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 99, "name": "University of Montpellier", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/University%20of%20Montpellier/?format=api" } ], "keywords": [ "Immunogenetics", "Immune repertoire analysis", "Immunoinformatics" ], "fields": [], "orgid": null, "tools": [ "imgt_3dstructure", "IMGT_HighV-QUEST", "IMGT_mAb-DB", "IMGT-ONTOLOGY", "imgt_v-quest" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/339/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/204/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/225/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/204/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/258/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/310/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/339/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/339/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "43.611242", "lng": "3.876733", "updated_at": "2025-12-09T10:08:12.617299Z" }, { "id": 20, "name": "PRABI-Lyon-Grenoble", "logo_url": null, "description": "Les thématiques de recherche du PRABI-Doua s’organisent autour d’un point de vue méthodologique, qui affirme l’importance de la modélisation tant mathématique qu’informatique et d’une perspective évolutive qui organise les recherches indépendamment du niveau d’organisation biologique. C’est dans la synergie entre des problématiques biologiques propres et des développements méthodologiques que naît la plus grande part des résultats scientifiques de cette composante. Parmi les thématiques abordées figurent en particulier:\r\nPhylogénie et évolution moléculaire.\r\nGénomique comparative (organismes eucaryotes et procaryotes).\r\nEléments transposables.\r\nIntreractions hôtes-parasites.\r\nStatistiques appliquées à l'écologie et l'évolution.\r\nAnalyse statistique de données en grandes dimensions pour la génomique.", "expertise": [], "expertise_description": "", "linkCovid19": "", "homepage": "http://doua.prabi.fr/main/index", "unitId": "", "address": "Université Claude Bernard – Lyon 1\r\n43 boulevard du 11 Novembre 1918\r\n69622 Villeurbanne\r\nFrance", "city": "Villeurbanne", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" }, { "id": 59, "name": "LBBE - Laboratory of Biometry and Evolutionary Biology", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/LBBE%20-%20Laboratory%20of%20Biometry%20and%20Evolutionary%20Biology/?format=api" } ], "publications": [ "" ], "certifications": [], "fundedBy": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" } ], "keywords": [], "fields": [ "Biologie", "Biomédical", "Agro-alimentaire", "Environnement" ], "orgid": null, "tools": [ "leBIBI", "seaview" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/489/?format=api" ], "technicalLeaders": [], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/190/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/263/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/311/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/329/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/345/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/352/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/382/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/412/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/163/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/425/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/71/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/80/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/155/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/572/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/577/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/442/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/485/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/498/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/590/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/203/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/222/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/229/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/271/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/546/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/600/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/104/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/220/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/489/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/628/?format=api" ], "maintainers": [], "ifbMembership": "None", "platforms": [], "is_active": false, "closing_date": "2023-03-15", "lat": "45.736972", "lng": "4.796028", "updated_at": "2025-10-21T13:07:13.059740Z" }, { "id": 21, "name": "PRABI-Lyon-Gerland", "logo_url": null, "description": "Le PRABI-Gerland https://prabi.ibcp.fr localisé à l'IBCP développe les bases de données dans le domaine infectieux, les méthodes de prédiction et d'optimisation des structures 3D de protéines ainsi que les outils et services s'y rapportant. Dans le domaine des services la spécificité de la PF est la bioinformatique structurale (Modélisation moléculaire, prédiction de structure) introduite sur Lyon dès 1986 (il y a 25 ans avant même que le mot n'existe...). Dans ce domaine, l’activité proposée par le PRABI-Gerland s’appuie sur les expertises suivantes:\r\n Prédiction de structure de protéines [G. Deléage]\r\n Modélisation moléculaire [E. Bettler, G. Deléage, R. Terreux]\r\n Intégration de méthodes et serveurs Web [C. Combet, G Deléage]\r\n Serveur Web 3D [E. Bettler, G. Deléage]\r\n Drug design et QSAR (R. Terreux, J.A. Chemelle)\r\n \r\nMots clefs: Bioinformatique structurale, Prédiction de structure, Base de données structurales, Analyse de séquences, Modélisation moléculaire, docking moléculaire.\r\n \r\nPrincipaux sites web: https://prabi.ibcp.fr (site en cours de refonte)\r\n https://geno3d-prabi.ibcp.fr/\r\n https://npsa-prabi.ibcp.fr/\r\n http://sumo-pbil.ibcp.fr\r\n http://espript.ibcp.fr\r\n http://endscript.ibcp.fr\r\nMéthodes de prédiction des structures secondaires de protéines.\r\nPlusieurs méthodes originales ont été développées, Self Optimized Prediction Method (SOPM), génère automatiquement à partir de cette base de donnée, une \"sous-base\" rassemblant les 60 à 80 protéines les plus homologues ou appartenant à la même classe structurale que la protéine\r\nétudiée. En effet, des protéines homologues ont généralement une structure assez proche (30% d'identité indique une architecture semblable). Après une phase d'apprentissage automatique sur cette \"sous-base\", en particulier d'optimisation des paramètres, la prédiction de la structure de la protéine est réalisée. La version SOPMA tire bénéfice des alignements multiples. La méthode MLRC combine les réseaux de neurones avec la méthode SOPMA.\r\n [SOPMA] Self optimised Prediction Method (1995)\r\n [SOPM] Self optimised Prediction Method (1994)\r\n [DPM] Double prediction Method (1987)\r\n [MLRC] Multivariate Linear Regression Combination (1999)\r\n [AMPHIPASEEK] Prediction of membrane anchor helical peptides (2006)\r\n \r\nIntégration de methodes- WebicielsServeur NPS@\r\nLe PRABI Gerland a développé le premier serveur de mail Français pour la prédiction de structures secondaires de protéines (80 000 prédictions en tout). Ensuite ces méthodes ont été intégrées dans [NPS@ 2000]. Le serveur est actuellement dans sa version 3. Dans le cadre de RENABI-IFB, ce serveur généraliste de séquences couplé aux prédictions de structures sera mis à jour en termes d’ergonomie, d’interface et de conception. Mise à disposition d’outils et de services en ligne correspondant aux domaines d’expertise du laboratoire d’accueil de la PF.\r\n \r\nServeur Web ESPript/ENDscript\r\nA partir d’une protéine de structure connue (code ou fichier PDB), le serveur ENDscript produit, en quelques secondes et de manière automatisée, plusieurs illustrations téléchargeables dans des formats usuels (PostScript, PDF, PNG et TIFF) :\r\n1/ Une première figure, générée par le logiciel ESPript, présente la séquence de la protéine d’intérêt agrémentée de ses éléments de structure secondaire, de l’accessibilité au solvant et de l’hydropathie par résidu. Si disponibles, sont aussi représentés les contacts cristallographiques et non-cristallographiques protéine/protéine et/ou protéine/ligand ainsi que les résidus impliqués dans des ponts disulfures.\r\n2/ Une seconde figure ESPript montre, en plus des informations précédentes, un alignement multiple de séquences des protéines homologues coloré en fonction de la conservation des résidus et agrémenté des éléments de structure secondaire de ces dernières si leurs structures sont connues. \r\n3/ Deux représentations 3D interactives visualisables par le logiciel PyMOL : a) une représentation en ruban, colorée en fonction de la conservation de séquence. b) une représentation en tube dont le diamètre est proportionnel à la déviation structurale (rmsd) entre la protéine d’intérêt et les protéines homologues de structure connue. De plus, si disponible, peuvent être affichés : l’assemblage de l’unité biologique, les modèles RMN multiples, les ligands et les résidus en contact avec ces derniers.\r\nLe serveur ESPript permet, en complément d’ENDscript ou de manière autonome, de représenter des alignements multiples de séquences avec la possibilité d’ajouter des marqueurs définis par l’utilisateur de manière à produire des figures facilitant l’analyse ou dédiées aux communications scientifiques.\r\n \r\nModélisation moléculaire\r\nUn serveur Web de modélisation moléculaire automatique de structure 3D de protéines appelé geno3D est disponible depsuis 2002 qui permet aux biologistes et biochimistes d'obtenir un modèle 3D de qualité si la séquence \"query\" présente plus de 35% d'identité avec une protéine de structure 3D connue. Le principe de cette modélisation consiste à appliquer les techniques de modélisation sous contraintes à la protéine à modéliser (de type RMN) à partir d'un jeu de contraintes calculées sur l'empreinte structurale. Plusieurs empreintes sont utilisables, le ligand (si présent) est replacé dans les modèles, 10 modèles sont générés. Les résultats sont proposés sous la forme d’une archive récupérable et les résultats sont conservés 8 jours sur le serveur. Ce serveur génère 100 modèles/mois. Un système intégré de modélisation moléculaire (MAGOS ) à grande échelle de protéomes entiers a été utilisé pour des protéomes de virus (modeome3D) et de plantes (arabidome3D).\r\n \r\nDocking et sites 3D- chemo-informatique\r\nUne méthode bioinformatique SUMO a été développée permettant de détecter des sites 3D fonctionnels communs à plusieurs protéines. L’approche a fait l’objet d’un brevet déposé par le CNRS et d'un serveur Web pour rendre utilisable la méthode par la communauté académique.\r\nDans un travail récent, nous avons réévalué les paramètres et avons montré que la qualité de comparaison était améliorée tout comme la rapidité du calcul. 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