Team List
Handles creating, reading and updating teams.
GET /api/team/?format=api&offset=20&ordering=-unitId
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Elle propose : le développement de méthodes/protocoles de bio-informatique structurelle, l'hébergement de services et le déploiement en ligne de services du domaine, la formation et conseil dans le domaine et l’hébergement de calculs via PAAS.", "expertise": [], "expertise_description": "", "linkCovid19": "", "homepage": "http://bioserv.rpbs.univ-paris-diderot.fr/index.html", "unitId": "", "address": "35 rue Hélène Brion", "city": "Paris", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 28, "name": "University Paris-Cité", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/University%20Paris-Cit%C3%A9/?format=api" }, { "id": 56, "name": "INSERM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INSERM/?format=api" } ], "publications": [ "" ], "certifications": [ "Label IBiSA" ], "fundedBy": [ { "id": 28, "name": "University Paris-Cité", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/University%20Paris-Cit%C3%A9/?format=api" }, { "id": 56, "name": "INSERM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INSERM/?format=api" } ], "keywords": [], "fields": [ "Biologie", "Biomédical", "Informatique" ], "orgid": null, "tools": [ "fpocket", "frog2", "hca", "hhalign-kbest", "interevdock2", "pep-fold", "pep-sitefinder", "sabbac" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/801/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/802/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/523/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/801/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/802/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/120/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/523/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/583/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/617/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/638/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/523/?format=api" ], "ifbMembership": "Member platform", "platforms": [], "is_active": true, "closing_date": null, "lat": "48.827664", "lng": "2.380355", "updated_at": "2025-10-21T13:07:13.178118Z" }, { "id": 1, "name": "EBIO", "logo_url": null, "description": "La plateforme Bioinformatique eBio (http://ebio.u-psud.fr/) créée en décembre 2009, est au centre du dispositif de bioinformatique de l’Université Paris-Sud. Elle est associée aux services de bioinformatiques de l’INRA Moulon, de l’hôpital Paul Brousse et de Gustave Roussy. eBio est labellisée par IBISA/Reseau National des Plateformes Bioinformatiques (RENABI) et membre de l’Alliance des Plateformes Bioinformatiques d’Ile de France (APLIBIO). Le site principal de eBio est localisé au bat 400 de l'Université Paris–Sud et intégré à l'I2BC (UMR9198, Gif sur Yvette).\r\nLes missions d’eBio comprennent : (1) le soutien bioinformatique aux projets de recherche, (2) la mise à disposition de moyens de calcul et stockage, (3) le développement et la maintenance de serveurs web de bioinformatique et bases de données de génomique. La plateforme a accompagné ou hébergé plus de 50 projets de recherche depuis début 2010.\r\nLes principaux domaines d’expertise de la plateforme sont les suivants :\r\n- L’analyse de données RNA-seq, notamment la detection de transcrits non codants, transcrits alternatifs, l’analyse d’expression différentielle, le ribosome profiling\r\n- L’analyse des structures d’ARN (alignement, structure secondaire)\r\n- L’intégration de logiciels et de workflows d’analyse sous Galaxy\r\n- L’assemblage des génomes de bactéries/champignons, la détection de variants\r\n- La phylogénie moléculaire et l’analyse fonctionnelle par profil phylogénétique\r\n- L’annotation des génomes de bactéries, archées et champignons (séquences CRISPR, terminateurs de transcription, ARN régulateurs, minisatellites)\r\n- Le calcul distribué et sur cloud (déploiement de services d’analyse sur cluster et cloud académique)", "expertise": [], "expertise_description": "", "linkCovid19": "", "homepage": "http://ebio.u-psud.fr/", "unitId": "", "address": "15 rue George Clémenceau\r\n91000 Orsay\r\nFrance", "city": "Orsay", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" } ], "publications": [ "" ], "certifications": [ "Label IBiSA" ], "fundedBy": [ { "id": 52, "name": "CNRS", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/CNRS/?format=api" } ], "keywords": [], "fields": [ "Biologie", "Biomédical", "Agro-alimentaire", "Environnement" ], "orgid": null, "tools": [ "crisprfinder", "erpin", "synttax" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/244/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/605/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/244/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/605/?format=api" ], "maintainers": [], "ifbMembership": "None", "platforms": [], "is_active": false, "closing_date": "2023-03-15", "lat": "48.698931", "lng": "2.177998", "updated_at": "2025-10-21T13:07:13.141581Z" }, { "id": 46, "name": "IMGT", "logo_url": "https://www.imgt.org/images/logo_IMGT.png", "description": "IMGT®, the international ImMunoGeneTics information system®, is the international reference in immunogenetics and immunoinformatics, created in 1989 at the University of Montpellier and the CNRS. IMGT® is a high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MH superfamily (MhSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates.", "expertise": [], "expertise_description": "The IMGT platform specializes in the nomenclature and classification of immunoglobulin genes and T cell receptors, facilitating research on the immune response. 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It brings together bioinformaticians from several units and institutes in Montpellier (CIRAD, INRAE, IRD, and the Alliance Bioversity International and CIAT), who have multidisciplinary expertise in data integration, software development, sequencing data analysis, and high-performance computing. The platform has developed strong expertise in building information systems and visualization tools such as Genome Hubs as well as analytical workflow genome analyses (rnaseq, assemby, pangenomics, phylogenomics etc.).", "expertise": [ "http://edamontology.org/topic_3316", "http://edamontology.org/topic_3474", "http://edamontology.org/topic_0114", "http://edamontology.org/topic_3673", "http://edamontology.org/topic_0194", "http://edamontology.org/topic_3517", "http://edamontology.org/topic_0769", "http://edamontology.org/topic_3050", "http://edamontology.org/topic_3068", "http://edamontology.org/topic_3299", "http://edamontology.org/topic_0219", "http://edamontology.org/topic_3308", "http://edamontology.org/topic_0092", "http://edamontology.org/topic_3071" ], "expertise_description": "Genomic analysis of plants and their pathogens, including genome assembly, phylogenomics, GWAS, and transcriptomics. We develop reproducible workflows (SnakeMake, Galaxy) and support the management, annotation, and curation of biological data. 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Le laboratoire comprend une installation de séquençage (TGML, membre de France Génomique) et une solide équipe de bio-informaticiens qui développent et donnent accès au public à des ressources bio-informatiques (outils logiciels et bases de données) dans des domaines allant de l'analyse de protéines individuelles et de séquences d'ADN à l'analyse à grande échelle et à l'intégration de données omiques, avec un accent particulier sur les variations du génome, la régulation génétique et épigénétique, et l'analyse de réseaux.", "expertise": [], "expertise_description": "coming soon", "linkCovid19": "", "homepage": "https://tagc.univ-amu.fr", "unitId": "", "address": "163 avenue de Luminy\r\nParc Scientifique de Luminy case 928", "city": "Marseille", "country": "France", "communities": [], "projects": [], "affiliatedWith": [ { "id": 56, "name": "INSERM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INSERM/?format=api" } ], "publications": [ "" ], "certifications": [], "fundedBy": [ { "id": 56, "name": "INSERM", "url": "https://catalogue.france-bioinformatique.fr/api/organisation/INSERM/?format=api" } ], "keywords": [ "Biostatistics", "Analysis of RNAseq data", "Systems Biology", "Genome analysis", "Transcript and transcript variant analysis", "Protein/protein interaction modelisation", "Single-Cell Analysis", "Workflow development", "Databases and information systems" ], "fields": [ "Biologie", "Biomédical" ], "orgid": null, "tools": [ "ledpred", "metamorf", "MoonDB", "ocg", "inserm-remap", "rsat" ], "services": [], "leaders": [], "deputies": [], "scientificLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/846/?format=api" ], "technicalLeaders": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/639/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/83/?format=api" ], "members": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/639/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/844/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/845/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/624/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/28/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/46/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/83/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/260/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/393/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/512/?format=api" ], "maintainers": [ "https://catalogue.france-bioinformatique.fr/api/userprofile/639/?format=api", "https://catalogue.france-bioinformatique.fr/api/userprofile/83/?format=api" ], "ifbMembership": "Associated Team", "platforms": [], "is_active": true, "closing_date": null, "lat": "43.231496", "lng": "5.441888", "updated_at": "2025-12-08T15:37:46.500141Z" }, { "id": 40, "name": "EvryRNA", "logo_url": null, "description": "EvryRNA platform is a web server providing various algorithms and bioinformatics tools developed in the laboratory IBISC of UEVE/Genopole, and dedicated to the prediction and the analysis of non-coding RNAs (ncRNAs). These RNAs are regulators of gene expression control and genome stability. They are involved in different biological processes, and some of them, including microRNAs, are known to be involved in many diseases such as cancer and neurodegenerative diseases. 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Elle a mis en place des procédures de contrôle qualité des échantillons à analyser. Elle dessine et automatise des pipelines d'analyse pour les données de génomique qu'elle reçoit.", "expertise": [], "expertise_description": "", "linkCovid19": "", "homepage": "http://www.synergielyoncancer.fr/", "unitId": "", "address": "28 rue Laënnec\r\nFondation Synergie Lyon Cancer, Bât. 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It is a team of the INRAE MIAT unit, part of the MathNum department and member of BioinfOmics (IR INRAE). It has been set up in 2000. Since 2009, it is one of the 13 IBISA bioinformatics platforms. Its missions are to provide computing and storage infrastructure dedicated to bioinformatics (software and databases are available on request) to approximately 1 200 users, to support biologists' projects mainly through collaboration and training, and to develop software for biologists and bioinformaticians.\r\nThe computing and storage infrastructure is composed by around 5000 cores, 83 Tera Byte memory and more than 7.5 Peta Byte disk space.", "expertise": [ "http://edamontology.org/topic_0091" ], "expertise_description": "The GenoToul bioinformatics facility provides access to high-performance computing resources, data analysis and programming expertise. Its permanent staff has many years of experience in supporting scientific programmes in biology and bioinformatics. 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The analysis of the many variations identified during the sequencing process of genes. In order to identify causative mutations, especially if they are missense mutations or null substitutions that only impact mRNA, we developed two tools: UMD-Predictor® to predict the pathogenicity of missense mutations, and the Human Splicing Finder® (HSF) to identify splicing signals and evaluate the impact of mutations on splicing.\r\n Locus Specific Databases (LSDBs). Since 1994, our team developed the Universal Mutation Database system (UMD®) an international reference system for the creation of Locus Specific Databases (LSDBs).\r\nPatient registries. We also developed through years, patient registries for neuromuscular rare diseases and others.", "expertise": [], "expertise_description": "The analysis of the many variations identified during the sequencing process of genes. 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Dans le domaine des services la spécificité de la PF est la bioinformatique structurale (Modélisation moléculaire, prédiction de structure) introduite sur Lyon dès 1986 (il y a 25 ans avant même que le mot n'existe...). Dans ce domaine, l’activité proposée par le PRABI-Gerland s’appuie sur les expertises suivantes:\r\n Prédiction de structure de protéines [G. Deléage]\r\n Modélisation moléculaire [E. Bettler, G. Deléage, R. Terreux]\r\n Intégration de méthodes et serveurs Web [C. Combet, G Deléage]\r\n Serveur Web 3D [E. Bettler, G. Deléage]\r\n Drug design et QSAR (R. Terreux, J.A. Chemelle)\r\n \r\nMots clefs: Bioinformatique structurale, Prédiction de structure, Base de données structurales, Analyse de séquences, Modélisation moléculaire, docking moléculaire.\r\n \r\nPrincipaux sites web: https://prabi.ibcp.fr (site en cours de refonte)\r\n https://geno3d-prabi.ibcp.fr/\r\n https://npsa-prabi.ibcp.fr/\r\n http://sumo-pbil.ibcp.fr\r\n http://espript.ibcp.fr\r\n http://endscript.ibcp.fr\r\nMéthodes de prédiction des structures secondaires de protéines.\r\nPlusieurs méthodes originales ont été développées, Self Optimized Prediction Method (SOPM), génère automatiquement à partir de cette base de donnée, une \"sous-base\" rassemblant les 60 à 80 protéines les plus homologues ou appartenant à la même classe structurale que la protéine\r\nétudiée. En effet, des protéines homologues ont généralement une structure assez proche (30% d'identité indique une architecture semblable). Après une phase d'apprentissage automatique sur cette \"sous-base\", en particulier d'optimisation des paramètres, la prédiction de la structure de la protéine est réalisée. La version SOPMA tire bénéfice des alignements multiples. La méthode MLRC combine les réseaux de neurones avec la méthode SOPMA.\r\n [SOPMA] Self optimised Prediction Method (1995)\r\n [SOPM] Self optimised Prediction Method (1994)\r\n [DPM] Double prediction Method (1987)\r\n [MLRC] Multivariate Linear Regression Combination (1999)\r\n [AMPHIPASEEK] Prediction of membrane anchor helical peptides (2006)\r\n \r\nIntégration de methodes- WebicielsServeur NPS@\r\nLe PRABI Gerland a développé le premier serveur de mail Français pour la prédiction de structures secondaires de protéines (80 000 prédictions en tout). Ensuite ces méthodes ont été intégrées dans [NPS@ 2000]. Le serveur est actuellement dans sa version 3. Dans le cadre de RENABI-IFB, ce serveur généraliste de séquences couplé aux prédictions de structures sera mis à jour en termes d’ergonomie, d’interface et de conception. Mise à disposition d’outils et de services en ligne correspondant aux domaines d’expertise du laboratoire d’accueil de la PF.\r\n \r\nServeur Web ESPript/ENDscript\r\nA partir d’une protéine de structure connue (code ou fichier PDB), le serveur ENDscript produit, en quelques secondes et de manière automatisée, plusieurs illustrations téléchargeables dans des formats usuels (PostScript, PDF, PNG et TIFF) :\r\n1/ Une première figure, générée par le logiciel ESPript, présente la séquence de la protéine d’intérêt agrémentée de ses éléments de structure secondaire, de l’accessibilité au solvant et de l’hydropathie par résidu. Si disponibles, sont aussi représentés les contacts cristallographiques et non-cristallographiques protéine/protéine et/ou protéine/ligand ainsi que les résidus impliqués dans des ponts disulfures.\r\n2/ Une seconde figure ESPript montre, en plus des informations précédentes, un alignement multiple de séquences des protéines homologues coloré en fonction de la conservation des résidus et agrémenté des éléments de structure secondaire de ces dernières si leurs structures sont connues. \r\n3/ Deux représentations 3D interactives visualisables par le logiciel PyMOL : a) une représentation en ruban, colorée en fonction de la conservation de séquence. b) une représentation en tube dont le diamètre est proportionnel à la déviation structurale (rmsd) entre la protéine d’intérêt et les protéines homologues de structure connue. De plus, si disponible, peuvent être affichés : l’assemblage de l’unité biologique, les modèles RMN multiples, les ligands et les résidus en contact avec ces derniers.\r\nLe serveur ESPript permet, en complément d’ENDscript ou de manière autonome, de représenter des alignements multiples de séquences avec la possibilité d’ajouter des marqueurs définis par l’utilisateur de manière à produire des figures facilitant l’analyse ou dédiées aux communications scientifiques.\r\n \r\nModélisation moléculaire\r\nUn serveur Web de modélisation moléculaire automatique de structure 3D de protéines appelé geno3D est disponible depsuis 2002 qui permet aux biologistes et biochimistes d'obtenir un modèle 3D de qualité si la séquence \"query\" présente plus de 35% d'identité avec une protéine de structure 3D connue. Le principe de cette modélisation consiste à appliquer les techniques de modélisation sous contraintes à la protéine à modéliser (de type RMN) à partir d'un jeu de contraintes calculées sur l'empreinte structurale. Plusieurs empreintes sont utilisables, le ligand (si présent) est replacé dans les modèles, 10 modèles sont générés. Les résultats sont proposés sous la forme d’une archive récupérable et les résultats sont conservés 8 jours sur le serveur. Ce serveur génère 100 modèles/mois. Un système intégré de modélisation moléculaire (MAGOS ) à grande échelle de protéomes entiers a été utilisé pour des protéomes de virus (modeome3D) et de plantes (arabidome3D).\r\n \r\nDocking et sites 3D- chemo-informatique\r\nUne méthode bioinformatique SUMO a été développée permettant de détecter des sites 3D fonctionnels communs à plusieurs protéines. L’approche a fait l’objet d’un brevet déposé par le CNRS et d'un serveur Web pour rendre utilisable la méthode par la communauté académique.\r\nDans un travail récent, nous avons réévalué les paramètres et avons montré que la qualité de comparaison était améliorée tout comme la rapidité du calcul. 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